دورية أكاديمية
أعرض في EDS

Hidden blood loss of total knee arthroplasty in hemophilia arthritis: an analysis of influencing factors.

التفاصيل البيبلوغرافية
العنوان: Hidden blood loss of total knee arthroplasty in hemophilia arthritis: an analysis of influencing factors.
المؤلفون: Shen SN; The First Clinical College of Zhejiang Chinese Medical University, The First Affiliated Hospital of Zhejiang Chinese Medical University, 548# BinWen Road, HangZhou, ZheJiang Province, People's Republic of China., Wu DX; The First Clinical College of Zhejiang Chinese Medical University, The First Affiliated Hospital of Zhejiang Chinese Medical University, 548# BinWen Road, HangZhou, ZheJiang Province, People's Republic of China., Lv SJ; The First Clinical College of Zhejiang Chinese Medical University, The First Affiliated Hospital of Zhejiang Chinese Medical University, 548# BinWen Road, HangZhou, ZheJiang Province, People's Republic of China., Tong PJ; The First Clinical College of Zhejiang Chinese Medical University, The First Affiliated Hospital of Zhejiang Chinese Medical University, 548# BinWen Road, HangZhou, ZheJiang Province, People's Republic of China. tongpeijian@163.com.
المصدر: BMC musculoskeletal disorders [BMC Musculoskelet Disord] 2022 Jun 17; Vol. 23 (1), pp. 587. Date of Electronic Publication: 2022 Jun 17.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100968565 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2474 (Electronic) Linking ISSN: 14712474 NLM ISO Abbreviation: BMC Musculoskelet Disord Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : BioMed Central, [2000-
مواضيع طبية MeSH: Antifibrinolytic Agents*/adverse effects , Arthritis*/etiology , Arthritis*/surgery , Arthroplasty, Replacement, Knee*/adverse effects , Hemophilia A*/complications , Hemophilia A*/drug therapy , Tranexamic Acid*/therapeutic use, Aged ; Blood Loss, Surgical/prevention & control ; Blood Transfusion ; Humans ; Postoperative Hemorrhage/prevention & control
مستخلص: Background: Total knee arthroplasty is the leading way to treat hemophilia arthritis. At present, there is a lack of research on the influencing factors of blood loss in total knee arthroplasty for hemophilia arthritis. This study comprehensively explores the definite factors affecting the hidden blood loss in total knee arthroplasty for hemophilia patients.
Materials and Methods: Ninety-two hemophilia A patients who underwent total knee arthroplasty in our center were included. Demographics, laboratory data, surgical data, and complications were collected. The Gross equation and Sehat equation were used to calculate the estimated value of hidden blood loss. Multivariate linear regression analysis was used to determine the influencing factors of hidden blood loss.
Result: The hidden blood loss of hemophilia A patients undergoing total knee arthroplasty was 1069.51 ± 341.99 mL, and the age was positively correlated with the hidden blood loss (P < 0.001), while tranexamic acid, FVIII prophylaxis, and incremental invivo recovery were negatively correlated with the hidden blood loss (P < 0.001, P = 0.008, P = 0.017).
Conclusion: Elderly patients have a greater risk of blood loss, and additional preventive measures can be appropriately added. Intraoperative intra-articular injection of tranexamic acid is recommended to reduce hidden blood loss, FVIII prophylaxis is recommended for every patient. We recommend that all HA patients measure the incremental invivo recovery and develop a personalized infusion regimen of coagulation factor.
(© 2022. The Author(s).)
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فهرسة مساهمة: Keywords: Hemophilia A; Hidden blood loss; Influential factor; Total joint arthroplasty
المشرفين على المادة: 0 (Antifibrinolytic Agents)
6T84R30KC1 (Tranexamic Acid)
تواريخ الأحداث: Date Created: 20220617 Date Completed: 20220621 Latest Revision: 20220716
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC9206270
DOI: 10.1186/s12891-022-05535-y
PMID: 35715793
قاعدة البيانات: MEDLINE
الوصف
تدمد:1471-2474
DOI:10.1186/s12891-022-05535-y