دورية أكاديمية
Hidden blood loss of total knee arthroplasty in hemophilia arthritis: an analysis of influencing factors.
العنوان: | Hidden blood loss of total knee arthroplasty in hemophilia arthritis: an analysis of influencing factors. |
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المؤلفون: | Shen SN; The First Clinical College of Zhejiang Chinese Medical University, The First Affiliated Hospital of Zhejiang Chinese Medical University, 548# BinWen Road, HangZhou, ZheJiang Province, People's Republic of China., Wu DX; The First Clinical College of Zhejiang Chinese Medical University, The First Affiliated Hospital of Zhejiang Chinese Medical University, 548# BinWen Road, HangZhou, ZheJiang Province, People's Republic of China., Lv SJ; The First Clinical College of Zhejiang Chinese Medical University, The First Affiliated Hospital of Zhejiang Chinese Medical University, 548# BinWen Road, HangZhou, ZheJiang Province, People's Republic of China., Tong PJ; The First Clinical College of Zhejiang Chinese Medical University, The First Affiliated Hospital of Zhejiang Chinese Medical University, 548# BinWen Road, HangZhou, ZheJiang Province, People's Republic of China. tongpeijian@163.com. |
المصدر: | BMC musculoskeletal disorders [BMC Musculoskelet Disord] 2022 Jun 17; Vol. 23 (1), pp. 587. Date of Electronic Publication: 2022 Jun 17. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: BioMed Central Country of Publication: England NLM ID: 100968565 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2474 (Electronic) Linking ISSN: 14712474 NLM ISO Abbreviation: BMC Musculoskelet Disord Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: London : BioMed Central, [2000- |
مواضيع طبية MeSH: | Antifibrinolytic Agents*/adverse effects , Arthritis*/etiology , Arthritis*/surgery , Arthroplasty, Replacement, Knee*/adverse effects , Hemophilia A*/complications , Hemophilia A*/drug therapy , Tranexamic Acid*/therapeutic use, Aged ; Blood Loss, Surgical/prevention & control ; Blood Transfusion ; Humans ; Postoperative Hemorrhage/prevention & control |
مستخلص: | Background: Total knee arthroplasty is the leading way to treat hemophilia arthritis. At present, there is a lack of research on the influencing factors of blood loss in total knee arthroplasty for hemophilia arthritis. This study comprehensively explores the definite factors affecting the hidden blood loss in total knee arthroplasty for hemophilia patients. Materials and Methods: Ninety-two hemophilia A patients who underwent total knee arthroplasty in our center were included. Demographics, laboratory data, surgical data, and complications were collected. The Gross equation and Sehat equation were used to calculate the estimated value of hidden blood loss. Multivariate linear regression analysis was used to determine the influencing factors of hidden blood loss. Result: The hidden blood loss of hemophilia A patients undergoing total knee arthroplasty was 1069.51 ± 341.99 mL, and the age was positively correlated with the hidden blood loss (P < 0.001), while tranexamic acid, FVIII prophylaxis, and incremental invivo recovery were negatively correlated with the hidden blood loss (P < 0.001, P = 0.008, P = 0.017). Conclusion: Elderly patients have a greater risk of blood loss, and additional preventive measures can be appropriately added. Intraoperative intra-articular injection of tranexamic acid is recommended to reduce hidden blood loss, FVIII prophylaxis is recommended for every patient. We recommend that all HA patients measure the incremental invivo recovery and develop a personalized infusion regimen of coagulation factor. (© 2022. The Author(s).) |
References: | Haemophilia. 2018 Mar;24(2):299-306. (PMID: 29193440) Bone Joint J. 2014 Aug;96-B(8):1005-15. (PMID: 25086114) JAMA. 2012 Oct 10;308(14):1452-9. (PMID: 23047359) Arthroplast Today. 2020 Apr 28;6(2):246-250. (PMID: 32577472) Zhonghua Xue Ye Xue Za Zhi. 2017 May 14;38(5):404-409. (PMID: 28565740) Arch Orthop Trauma Surg. 2000;120(9):518-20. (PMID: 11011672) Haemophilia. 2002 May;8(3):387-92. (PMID: 12010439) Arch Bone Jt Surg. 2016 Jan;4(1):65-9. (PMID: 26894222) Br J Haematol. 2001 Apr;113(1):24-31. (PMID: 11328275) Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2012 Dec;34(6):613-6. (PMID: 23286409) Haemophilia. 2016 Jul;22(4):e275-85. (PMID: 27444973) Blood Rev. 2019 May;35:43-50. (PMID: 30922616) Haemophilia. 2016 Nov;22(6):919-924. (PMID: 27561958) Nature. 2021 Mar;591(7848):117-123. (PMID: 33442062) Anesthesiology. 1983 Mar;58(3):277-80. (PMID: 6829965) Haemophilia. 2013 Jan;19(1):e1-47. (PMID: 22776238) Lancet. 2012 Apr 14;379(9824):1447-56. (PMID: 22456059) J Orthop Surg (Hong Kong). 2019 Sep-Dec;27(3):2309499019874931. (PMID: 31554469) Semin Thromb Hemost. 2005 Nov;31(5):527-37. (PMID: 16276461) J Arthroplasty. 2014 Aug;29(8):1521-4. (PMID: 24726174) Knee. 2000 Jul 1;7(3):151-155. (PMID: 10927208) J Pediatr Hematol Oncol. 2015 Mar;37(2):e80-5. (PMID: 25000469) BMC Musculoskelet Disord. 2019 Sep 4;20(1):402. (PMID: 31481049) J Arthroplasty. 2018 Oct;33(10):3090-3098.e1. (PMID: 29805106) Expert Rev Hematol. 2020 Mar;13(3):269-274. (PMID: 31935128) J Orthop Surg (Hong Kong). 2019 Jan-Apr;27(1):2309499019834337. (PMID: 30852987) Blood Transfus. 2019 Nov;17(6):479-486. (PMID: 31846611) Jt Dis Relat Surg. 2020;31(3):488-493. (PMID: 32962580) |
فهرسة مساهمة: | Keywords: Hemophilia A; Hidden blood loss; Influential factor; Total joint arthroplasty |
المشرفين على المادة: | 0 (Antifibrinolytic Agents) 6T84R30KC1 (Tranexamic Acid) |
تواريخ الأحداث: | Date Created: 20220617 Date Completed: 20220621 Latest Revision: 20220716 |
رمز التحديث: | 20231215 |
مُعرف محوري في PubMed: | PMC9206270 |
DOI: | 10.1186/s12891-022-05535-y |
PMID: | 35715793 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1471-2474 |
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DOI: | 10.1186/s12891-022-05535-y |