دورية أكاديمية
Stereoselective Desymmetrizations of Dinitriles to Synthesize Lactones.
| العنوان: | Stereoselective Desymmetrizations of Dinitriles to Synthesize Lactones. |
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| المؤلفون: | Kelley AM; The University of North Carolina at Greensboro., Frost JA; The University of North Carolina at Greensboro., Baber TM; The University of North Carolina at Greensboro., Youngblood KC; The University of North Carolina at Greensboro., Michishita E; The University of North Carolina at Greensboro., Bain SA; The University of North Carolina at Greensboro., Lykins TC; The University of North Carolina at Greensboro., Petersen KS; The University of North Carolina at Greensboro. |
| المصدر: | Tetrahedron letters [Tetrahedron Lett] 2022 Jan 05; Vol. 88. Date of Electronic Publication: 2021 Dec 03. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: England NLM ID: 2984819R Publication Model: Print-Electronic Cited Medium: Print ISSN: 0040-4039 (Print) Linking ISSN: 00404039 NLM ISO Abbreviation: Tetrahedron Lett Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Publication: Oxford : Elsevier Original Publication: Oxford, New York, Pergamon Press. |
| مستخلص: | Nitriles are important organic functional groups, allowing for installation of nitrogen in organic synthesis. The Pinner reaction transforms nitriles into esters via the imidate group, but in general has previously necessitated harsh acid conditions. This work builds on the utility of the Pinner reaction through a stereoselective desymmetrization of dinitriles to form γ- and δ-lactones in good yields and diastereoselectivites. |
| References: | Org Biomol Chem. 2019 Oct 21;17(39):8853-8857. (PMID: 31573594) Drug Discov Today. 2013 Sep;18(17-18):894-905. (PMID: 23688583) Org Lett. 2011 Feb 4;13(3):374-7. (PMID: 21188969) J Nat Prod. 2012 Sep 28;75(9):1578-83. (PMID: 22938151) Nat Prod Rep. 2015 Jul;32(7):1042-66. (PMID: 25976887) J Hematol Oncol. 2016 Sep 22;9(1):93. (PMID: 27658462) |
| معلومات مُعتمدة: | R15 GM141981 United States GM NIGMS NIH HHS; T32 AT008938 United States AT NCCIH NIH HHS; T34 GM113860 United States GM NIGMS NIH HHS |
| فهرسة مساهمة: | Keywords: Desymmetrization; Diastereoselective; Lactones; Pinner Reaction |
| تواريخ الأحداث: | Date Created: 20220620 Latest Revision: 20230106 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC9205472 |
| DOI: | 10.1016/j.tetlet.2021.153573 |
| PMID: | 35719215 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0040-4039 |
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| DOI: | 10.1016/j.tetlet.2021.153573 |