تقرير
Genetic sub-structuring of Croatian island populations in the Southeastern European context: a meta-analysis.
| العنوان: | Genetic sub-structuring of Croatian island populations in the Southeastern European context: a meta-analysis. |
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| المؤلفون: | Novokmet N; Natalija Novokmet, Institute for Anthropological Research, Ljudevita Gaja 32, 10000 Zagreb, Croatia, natalija.novokmet@inantro.hr., Galov A, Škaro V, Projić P, Šarac J, Havaš Auguštin D, Rudan P, Primorac D, Marjanović D |
| المصدر: | Croatian medical journal [Croat Med J] 2022 Jun 22; Vol. 63 (3), pp. 231-243. |
| نوع المنشور: | Meta-Analysis |
| اللغة: | English |
| بيانات الدورية: | Publisher: Medicinska Naklada Country of Publication: Croatia NLM ID: 9424324 Publication Model: Print Cited Medium: Internet ISSN: 1332-8166 (Electronic) Linking ISSN: 03539504 NLM ISO Abbreviation: Croat Med J Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2001- : Zagreb : Medicinska Naklada Original Publication: Zagreb : University of Zagreb Medical School, [1992- |
| مواضيع طبية MeSH: | DNA Fingerprinting* , Genetics, Population*, Bosnia and Herzegovina ; Croatia ; Europe ; Gene Frequency ; Humans ; Microsatellite Repeats |
| مستخلص: | Aim: To use the method of meta-analysis to assess the influence of island population isolation on the sub-structuring of the Croatian population, as well as the influence of regional population groups on the sub-structuring of the Southeastern European population with regard to basic population genetic statistical parameters calculated by using STR locus analysis. Methods: Bio-statistical analyses were performed for 2877 unrelated participants of both sexes from Southeastern Europe. Nine autosomal STR loci (D3S1358, vWA, FGA, TH01, TPOX, CSF1PO, D5S818, D13S317, and D7S82) were analyzed by using standard F-statistics and population structure analysis (Structure software). Results: Genetic differentiation of Croatian subpopulations assessed with the FST method was higher at the level of the Croatian population (0.005) than at the level of Southeastern Europe (0.002). The island of Vis showed the most pronounced separation in the Croatian population, and Albanians from Kosovo in the population of Southeast Europe, followed by Croatia, Bosnia and Herzegovina, and Hungary. Conclusion: The higher structure of Croatian subpopulations in relation to Southeastern Europe suggest a certain degree of genetic isolation, most likely due to the influence of endogamy within rural island populations. |
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| تواريخ الأحداث: | Date Created: 20220620 Date Completed: 20220621 Latest Revision: 20220731 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC9284015 |
| PMID: | 35722692 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1332-8166 |
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