دورية أكاديمية
أعرض في EDS

Clinical Characteristics and Stage at Presentation of Glaucoma Patients in Sub-Saharan Africa.

التفاصيل البيبلوغرافية
العنوان: Clinical Characteristics and Stage at Presentation of Glaucoma Patients in Sub-Saharan Africa.
المؤلفون: Olawoye O; Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queens University Belfast, UK.; Department of Ophthalmology, College of Medicine., Kizor-Akaraiwe N; Department of Ophthalmology, College of Medicine, Enugu State University of Technology.; The Eye Specialists Hospital (TESH)., Pons J; Good Shepherd Hospital, Siteki, Eswatini., Sarimiye T; Department of Ophthalmology, College of Medicine., Washaya J; Department of Ophthalmology University of Zimbabwe, Zimbabwe., Hughes S; Department of Ophthalmology, College of Medicine., Ashaye A; Department of Ophthalmology, College of Medicine., Garba F; Department of Ophthalmology, College of Medical Sciences, Ahmadu Bello University, Zaria., Gessesse GW; St Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia., Chitedze R; The Eyes of Africa, Childlegacy International., Ibanga A; Department of Ophthalmology, College of medical Sciences, University of Calabar, Calabar., Saka V; Eyes of Africa, Malawi., Agre J; Centre d' Ophtalmologie Siloam Abidjan, Côté D Ivoire, West Africa., Mahdi A; Department of Ophthalmology, Abubakar Tafawa Balewa University Teaching Hospital, Bauchi., Ogunro A; Eye Foundation Hospital Group., Budengeri P; Clinique de l'Oeil de, Bujumbura, Burundi., Ajibode HA; Department of Ophthalmology, Olabisi Onabanjo University Teaching Hospital, Sagamu., Tamrat L; St Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia., Onakoya A; Department of Ophthalmology, Lagos University Teaching Hospital Idi Araba, Lagos., Okeke S; Enugu State University of Science and Technology., Hulley JA; The Eye Centre, East London, South Africa., Giorgis A; Department of ophthalmology, SM, CHS, Addis Ababa University, Addis Ababa, Ethiopia., Onyekachi IW; Department of Ophthalmology, Alex Ekwueme Federal University Teaching Hospital Abakaliki, Ebonyi State., Okosa CC; Department of Ophthalmology, College of Medicine, University of Nigeria, Ituku Ozalla Campus, Enugu., Ogbonnaya C; Department of Ophthalmology, Ebonyi State University, Abakaliki., Abdulsalam S; Department of Ophthalmology, College of Health Sciences, Bayero University Kano, Kano, Nigeria., Fowobaje K; Department of Epidemiology and Medical Statistics, Faculty of Public Health, College of Medicine, University of Ibadan, Ibadan., Cook S; The Eye Centre, East London, South Africa., Lawrence S; St Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.; Department of Ophthalmology and Visual Sciences, University of Michigan Medical School, Ann Arbor, MI., Macheka B; Sekuru Kaguvi Hospital, Harare, Zimbabwe., Chan VF; Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queens University Belfast, UK., Blanco AA; Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queens University Belfast, UK., Congdon N; Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queens University Belfast, UK.; Orbis International, New York, NY., Realini T; Department of Ophthalmology and Visual Sciences, West Virginia University, Morgantown, WV.
مؤلفون مشاركون: STAGE Research Group
المصدر: Journal of glaucoma [J Glaucoma] 2022 Sep 01; Vol. 31 (9), pp. 717-723. Date of Electronic Publication: 2022 Jun 27.
نوع المنشور: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 9300903 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1536-481X (Electronic) Linking ISSN: 10570829 NLM ISO Abbreviation: J Glaucoma Subsets: MEDLINE
أسماء مطبوعة: Publication: <2015- > : Philadelphia, PA : Wolters Kluwer Health, Inc.
Original Publication: New York, N.Y. : Raven Press, c1992-
مواضيع طبية MeSH: Glaucoma*/complications , Glaucoma*/diagnosis , Glaucoma, Open-Angle*/complications , Glaucoma, Open-Angle*/diagnosis, Aged ; Blindness/diagnosis ; Blindness/epidemiology ; Blindness/etiology ; Cross-Sectional Studies ; Humans ; Intraocular Pressure ; Middle Aged
مستخلص: Prcis: The initial presentation of glaucoma varies meaningfully across SSA. A comprehensive strategy with regional customization based on local differences is needed to reduce glaucoma blindness in SSA.
Purpose: To explore regional variations in the presentation of newly diagnosed glaucoma in Sub Saharan Africa (SSA).
Methodology: This was a multicenter, cross-sectional study in which newly diagnosed, consecutive, glaucoma patients aged older than or equal to 18 years were recruited from 27 eye clinics in 10 countries throughout SSA. Demographic and ophthalmic examination data were collected. Glaucoma severity was based on optic nerve head and visual field assessment. Statistical analyses were performed using STATA version 14.0.
Results: Among 1214 enrolled patients with newly diagnosed glaucoma from Western, Eastern, and Southern Africa, the overall mean (SD) age was 59.9 (17.1) years. More than half of all patients (716/1178; 60.8%) presented with severe glaucoma in the worse eye, and one-third (36.9%) had severe glaucoma in both eyes. Primary open angle glaucoma was the commonest form of glaucoma in all regions (77.4%). A family history of blindness (260/1204, 21.6%) was common. Patients from Western Africa had lower mean presenting intraocular pressure (26.4 [11.1] mm Hg, P <0.001), but had worse glaucoma in the better eye based on mean cup-disc ratio (0.8; P <0.001) and mean visual field mean deviation [10.4 (8.4)] dB, P =0.016) compared with other regions. Exfoliation glaucoma was more common in Eastern Africa (30/170=17.7%, P <0.001) compared with other regions.
Conclusion: The initial presentation of glaucoma varies meaningfully across SSA. A comprehensive strategy with regional customization based on local differences is needed to reduce glaucoma blindness in SSA.
Competing Interests: Disclosure: N.C. serves as a paid consultant for Belkin Vision, a company selling devices for the treatment of glaucoma. The remaining authors declare no conflict of interest.
(Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.)
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تواريخ الأحداث: Date Created: 20220627 Date Completed: 20220908 Latest Revision: 20221003
رمز التحديث: 20231215
DOI: 10.1097/IJG.0000000000002068
PMID: 35758429
قاعدة البيانات: MEDLINE
الوصف
تدمد:1536-481X
DOI:10.1097/IJG.0000000000002068