تقرير
Reactivation of Herpes Simplex Keratitis on a Corneal Graft Following SARS-CoV-2 mRNA Vaccination.
| العنوان: | Reactivation of Herpes Simplex Keratitis on a Corneal Graft Following SARS-CoV-2 mRNA Vaccination. |
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| المؤلفون: | Al-Dwairi RA; Department of Special Surgery, Division of Ophthalmology, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan., Aleshawi A; Department of Special Surgery, Division of Ophthalmology, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan., Adi S; Department of Special Surgery, Division of Ophthalmology, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan., Abu-Zreig L; Department of Special Surgery, Division of Ophthalmology, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan. |
| المصدر: | Medical archives (Sarajevo, Bosnia and Herzegovina) [Med Arch] 2022 Apr; Vol. 76 (2), pp. 146-148. |
| نوع المنشور: | Case Reports |
| اللغة: | English |
| بيانات الدورية: | Publisher: Academy of Medical Sciences of Bosnia and Herzegovina Country of Publication: Bosnia and Herzegovina NLM ID: 101635337 Publication Model: Print Cited Medium: Internet ISSN: 1986-5961 (Electronic) Linking ISSN: 0350199X NLM ISO Abbreviation: Med Arch Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Sarajevo, Bosnia and Herzegovina : Academy of Medical Sciences of Bosnia and Herzegovina Original Publication: Sarajevo, Bosnia and Herzegovina : Avicena, 2012- |
| مواضيع طبية MeSH: | COVID-19* , Keratitis, Herpetic*/drug therapy , Keratitis, Herpetic*/etiology , Keratitis, Herpetic*/prevention & control, Acyclovir/therapeutic use ; Antiviral Agents/therapeutic use ; COVID-19 Vaccines/adverse effects ; Humans ; Male ; Middle Aged ; RNA, Messenger ; Recurrence ; SARS-CoV-2 ; Vaccination ; Vaccines, Synthetic ; mRNA Vaccines |
| مستخلص: | Background: Ocular herpes simplex is usually caused by herpes simplex virus type 1 (HSV-1) and less commonly by the type 2 virus (HSV-2). Ocular manifestations of HSV include blepharitis, conjunctivitis, lacrimal system obstruction, corneal involvement, and uveitis. Corneal involvement is one of the causes of loss of vision and can be epithelial herpetic keratitis or stromal herpetic keratitis. Objective: A significant population has a colonization of herpes viruses. Under certain circumstances, these viruses can reactivate with a significant ocular morbidity. Globally, COVID-19 vaccines are recommended; however, the vaccine safety data are limited. Case Report: Herein, we reported a case of herpetic keratitis reactivation that occurred 2 days after receiving SARS-CoV-2 mRNA vaccine. The patient is a 50-year-old man who underwent penetrating keratoplasty (PKP) in 2020 for corneal opacity caused by a previous herpes simplex keratitis in 2013. Herpetic keratitis was treated successfully with topical antiviral acyclovir along with topical moxifloxacin and artificial tears. After treatment, prophylactic oral acyclovir was started. Conclusion: Both ophthalmologist and patients should be aware of this phenomenon. Long-term prophylactic antiviral treatment may be recommended for those patients. (© 2022 Rami A. Al-Dwairi1, Abdelwahab Aleshawi, Sharaf Adi, Laith Abu-Zreig.) |
| References: | J Ophthalmic Inflamm Infect. 2021 Sep 17;11(1):33. (PMID: 34533628) Ocul Immunol Inflamm. 2019;27(4):521-523. (PMID: 30153765) BMJ Clin Evid. 2008 Jul 23;2008:. (PMID: 19445742) Br J Ophthalmol. 2021 Jul;105(7):893-896. (PMID: 33910885) Am J Ophthalmol. 1968 Apr;65(4):533-41. (PMID: 5300433) Ocul Immunol Inflamm. 2021 Aug 18;29(6):1238-1240. (PMID: 34637667) IDCases. 2016 Sep 22;6:47-51. (PMID: 27699152) BMJ Case Rep. 2021 Sep 7;14(9):. (PMID: 34493563) Vaccines (Basel). 2021 Nov 25;9(12):. (PMID: 34960139) Ocul Immunol Inflamm. 2021 Aug 18;29(6):1216-1224. (PMID: 34559576) |
| فهرسة مساهمة: | Keywords: COVID-19; Penetrating keratoplasty; cornea; herpes simplex keratitis; vaccination |
| المشرفين على المادة: | 0 (Antiviral Agents) 0 (COVID-19 Vaccines) 0 (RNA, Messenger) 0 (Vaccines, Synthetic) 0 (mRNA Vaccines) X4HES1O11F (Acyclovir) |
| تواريخ الأحداث: | Date Created: 20220701 Date Completed: 20220704 Latest Revision: 20231213 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC9233471 |
| DOI: | 10.5455/medarh.2022.76.146-148 |
| PMID: | 35774041 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1986-5961 |
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| DOI: | 10.5455/medarh.2022.76.146-148 |