دورية أكاديمية
أعرض في EDS

Long-term Survival Following Heart Transplantation for Chagas Versus Non-Chagas Cardiomyopathy: A Single-center Experience in Northeastern Brazil Over 2 Decades.

التفاصيل البيبلوغرافية
العنوان: Long-term Survival Following Heart Transplantation for Chagas Versus Non-Chagas Cardiomyopathy: A Single-center Experience in Northeastern Brazil Over 2 Decades.
المؤلفون: Vieira JL; Heart Failure Division, Hospital de Messejana Dr Carlos Alberto Studart, Fortaleza, Ceará, Brazil., Sobral MGV; Heart Failure Division, Hospital de Messejana Dr Carlos Alberto Studart, Fortaleza, Ceará, Brazil., Macedo FY; Structural and Congenital Heart Center, Hackensack University Medical Center, Hackensack, NJ., Florêncio RS; Heart Failure Division, Hospital de Messejana Dr Carlos Alberto Studart, Fortaleza, Ceará, Brazil., Almeida GPL; Heart Failure Division, Hospital de Messejana Dr Carlos Alberto Studart, Fortaleza, Ceará, Brazil., Vasconcelos GG; Heart Failure Division, Hospital de Messejana Dr Carlos Alberto Studart, Fortaleza, Ceará, Brazil., Fernandes JR; Heart Failure Division, Hospital de Messejana Dr Carlos Alberto Studart, Fortaleza, Ceará, Brazil., Marinho LLE; Heart Failure Division, Hospital de Messejana Dr Carlos Alberto Studart, Fortaleza, Ceará, Brazil., Trompieri DFM; Heart Failure Division, Hospital de Messejana Dr Carlos Alberto Studart, Fortaleza, Ceará, Brazil., Pasala TKR; Structural and Congenital Heart Center, Hackensack University Medical Center, Hackensack, NJ., Mejia JAC; Heart Failure Division, Hospital de Messejana Dr Carlos Alberto Studart, Fortaleza, Ceará, Brazil., Souza-Neto JD; Heart Failure Division, Hospital de Messejana Dr Carlos Alberto Studart, Fortaleza, Ceará, Brazil.
المصدر: Transplantation direct [Transplant Direct] 2022 Jun 24; Vol. 8 (7), pp. e1349. Date of Electronic Publication: 2022 Jun 24 (Print Publication: 2022).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Wolters Kluwer Country of Publication: United States NLM ID: 101651609 Publication Model: eCollection Cited Medium: Print ISSN: 2373-8731 (Print) Linking ISSN: 23738731 NLM ISO Abbreviation: Transplant Direct Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: [Philadelphia, Pa.] : Wolters Kluwer, [2015]-
مستخلص: Data on post-heart transplant (HT) survival of patients with Chagas cardiomyopathy (CC) are scarce. We sought to evaluate post-HT survival in patients with CC as compared with other causes of heart failure across different eras of HT.
Methods: We conducted a retrospective, cohort study of 376 adult HT recipients between October 1997 and November 2019. Participants were classified according to the etiology of heart failure as CC (N = 66), nonischemic cardiomyopathy (N = 214), and ischemic cardiomyopathy (N = 96), and according to the era of HT as early (1997-2009), recent (2010-2014), and current era (2015-2019).
Results: After a mean follow-up of 5.0 y (0-20.5 y), post-HT survival rates at 1, 5, and 10 y were comparable between groups. One-y survival improved from 70% in the early eras to 80% in the current era (hazard ratio [HR], 0.63; 95% confidence interval [CI], 0.41-0.97; P  = 0.034). After adjustment for sex, age, and mechanical circulatory support, time-related improvement in survival was observed only in patients without CC (HR, 0.54; 95% CI, 0.32-0.91; P  = 0.019) but not in those with CC (HR, 0.99; 95% CI, 0.36-2.73; P  = 0.98). Causes of death were similar between patients with CC and the other etiological subgroups.
Conclusions: Posttransplant survival is comparable between patients with CC, nonischemic cardiomyopathy, and ischemic cardiomyopathy. Although survival has improved significantly over years for most HT recipients, it has remained unchanged for those with Chagas disease. These trends underscore the importance of scientific research, policy discussions and a collaborative registry of heart transplantation in Chagas cardiomyopathy.
Competing Interests: The authors declare no funding or conflicts of interest.
(Copyright © 2022 The Author(s). Transplantation Direct. Published by Wolters Kluwer Health, Inc.)
References: J Heart Lung Transplant. 2010 Mar;29(3):286-90. (PMID: 19783174)
J Am Coll Cardiol. 2013 Aug 27;62(9):767-76. (PMID: 23770163)
J Heart Lung Transplant. 2007 Dec;26(12):1229-42. (PMID: 18096473)
Infect Control Hosp Epidemiol. 2015 Dec;36(12):1444-50. (PMID: 26383964)
Artif Organs. 2007 Apr;31(4):245-8. (PMID: 17437490)
Int J Cardiol. 2013 Jul 31;167(2):486-90. (PMID: 22365646)
Circulation. 2010 Sep 14;122(11 Suppl):S85-91. (PMID: 20837931)
Arq Bras Cardiol. 2020 Dec;115(6):1193-1196. (PMID: 33470324)
J Heart Lung Transplant. 2010 Apr;29(4):449-53. (PMID: 20006935)
Circulation. 2018 Sep 18;138(12):e169-e209. (PMID: 30354432)
Int J Cardiol. 2008 Mar 28;125(1):142-3. (PMID: 17399819)
Arq Bras Cardiol. 2011 Dec;97(6):517-25. (PMID: 22030565)
Circulation. 2021 Mar 2;143(9):875-877. (PMID: 33378214)
Curr Heart Fail Rep. 2019 Feb;16(1):7-11. (PMID: 30712146)
Clin Transplant. 2018 Jun;32(6):e13279. (PMID: 29744939)
J Heart Lung Transplant. 2001 Jun;20(6):637-45. (PMID: 11404169)
J Am Coll Cardiol. 2017 Sep 19;70(12):1510-1524. (PMID: 28911515)
Arq Bras Cardiol. 2018 Sep;111(3):436-539. (PMID: 30379264)
Am J Cardiol. 2010 Apr 1;105(7):1024-9. (PMID: 20346325)
Ann Thorac Surg. 2001 Jun;71(6):1833-8. (PMID: 11426756)
Circ Heart Fail. 2018 Mar;11(3):e004173. (PMID: 29664403)
Am J Transplant. 2016 Dec;16(12):3490-3503. (PMID: 27163483)
Am J Transplant. 2013 Dec;13(12):3262-8. (PMID: 24165397)
Arq Bras Cardiol. 2011;97(2 Suppl 3):1-48. (PMID: 21952638)
Curr Cardiol Rep. 2019 Feb 12;21(2):8. (PMID: 30747287)
Circ Heart Fail. 2019 Oct;12(10):e006218. (PMID: 31597452)
Curr Opin Organ Transplant. 2021 Feb 1;26(1):69-76. (PMID: 33278151)
Prog Cardiovasc Dis. 2020 Sep - Oct;63(5):630-639. (PMID: 32971112)
Transpl Infect Dis. 2021 Aug;23(4):e13549. (PMID: 33345420)
N Engl J Med. 2020 Mar 5;382(10):972-973. (PMID: 32130822)
Circ Heart Fail. 2015 Sep;8(5):938-43. (PMID: 26206855)
Arq Bras Cardiol. 2018 Aug;111(2):230-289. (PMID: 30335870)
Circ Heart Fail. 2010 Jan;3(1):82-8. (PMID: 19933408)
Am J Transplant. 2005 Aug;5(8):2017-21. (PMID: 15996254)
J Heart Lung Transplant. 2005 May;24(5):517-25. (PMID: 15896747)
Transplant Proc. 2011 Jan-Feb;43(1):220-4. (PMID: 21335192)
Int J Cardiol. 1997 Jul 25;60(2):187-93. (PMID: 9226290)
Circ Heart Fail. 2017 Nov;10(11):. (PMID: 29141857)
J Thorac Cardiovasc Surg. 2010 Apr;139(4):1064-9. (PMID: 20138635)
J Card Fail. 2009 Apr;15(3):249-55. (PMID: 19327627)
Int J Cardiol. 2005 Jul 10;102(2):239-47. (PMID: 15982491)
Transplant Proc. 2019 Dec;51(10):3412-3417. (PMID: 31733797)
Ann Thorac Surg. 1996 Jun;61(6):1727-33. (PMID: 8651775)
J Heart Lung Transplant. 2017 Jun;36(6):597-603. (PMID: 28284779)
J Card Fail. 2018 Dec;24(12):860-863. (PMID: 30539718)
BMC Health Serv Res. 2018 Feb 7;18(1):90. (PMID: 29415705)
Transplantation. 2001 Nov 27;72(10):1662-5. (PMID: 11726828)
Lancet. 2011 May 21;377(9779):1778-97. (PMID: 21561655)
Circ Cardiovasc Qual Outcomes. 2016 Nov;9(6):695-703. (PMID: 27803093)
J Heart Lung Transplant. 2019 Oct;38(10):1056-1066. (PMID: 31548031)
Curr Probl Cardiol. 2021 Mar;46(3):100507. (PMID: 31983471)
Int J Cardiol. 2013 Oct 3;168(3):2375-80. (PMID: 23465560)
تواريخ الأحداث: Date Created: 20220701 Latest Revision: 20220716
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC9236606
DOI: 10.1097/TXD.0000000000001349
PMID: 35774419
قاعدة البيانات: MEDLINE
الوصف
تدمد:2373-8731
DOI:10.1097/TXD.0000000000001349