دورية أكاديمية
Ischemic preconditioning does not prevent placental dysfunction induced by fetal cardiac bypass.
العنوان: | Ischemic preconditioning does not prevent placental dysfunction induced by fetal cardiac bypass. |
---|---|
المؤلفون: | Assad RS; Laboratory of Cardiovascular Research, Heart Institute University of São Paulo, São Paulo, Brazil., Guedes MGA; Laboratory of Cardiovascular Research, Heart Institute University of São Paulo, São Paulo, Brazil., Aiello VD; Division of Pathology, Heart Institute University of São Paulo, São Paulo, Brazil., Thomaz PG; Laboratory of Cardiovascular Research, Heart Institute University of São Paulo, São Paulo, Brazil., Zanoni FL; Laboratory of Cardiovascular Research, Heart Institute University of São Paulo, São Paulo, Brazil., Saito M; Laboratory of Cardiovascular Research, Heart Institute University of São Paulo, São Paulo, Brazil., da Silva APN; Laboratory of Cardiovascular Research, Heart Institute University of São Paulo, São Paulo, Brazil., Coutinho E Silva RDS; Laboratory of Cardiovascular Research, Heart Institute University of São Paulo, São Paulo, Brazil., Pinto MV; Laboratory of Cardiovascular Research, Heart Institute University of São Paulo, São Paulo, Brazil., Jatene MB; Division of Pediatric Cardiac Surgery, Heart Institute University of São Paulo, São Paulo, Brazil., Moreira LFP; Laboratory of Cardiovascular Research, Heart Institute University of São Paulo, São Paulo, Brazil. |
المصدر: | Journal of cardiac surgery [J Card Surg] 2022 Sep; Vol. 37 (9), pp. 2592-2599. Date of Electronic Publication: 2022 Jul 01. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 8908809 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-8191 (Electronic) Linking ISSN: 08860440 NLM ISO Abbreviation: J Card Surg Subsets: MEDLINE |
أسماء مطبوعة: | Publication: Hoboken, NJ : Wiley-Blackwell Original Publication: Mount Kisco, N.Y. : Futura Pub. Co., Inc., [c1986- |
مواضيع طبية MeSH: | Ischemic Preconditioning* , Vascular Cell Adhesion Molecule-1*, Animals ; Female ; Fetus ; Interleukin-1 ; Placenta ; Pregnancy ; Sheep |
مستخلص: | Background: Remote ischemic preconditioning (rIPC) has been applied to attenuate tissue injury. We tested the hypothesis that rIPC applied to fetal lambs undergoing cardiac bypass (CB) reduces fetal systemic inflammation and placental dysfunction. Methods: Eighteen fetal lambs were divided into three groups: sham, CB control, and CB rIPC. CB rIPC fetuses had a hindlimb tourniquet applied to occlude blood flow for four cycles of a 5-min period, followed by a 2-min reperfusion period. Both study groups underwent 30 min of normothermic CB. Fetal inflammatory markers, gas exchange, and placental and fetal lung morphological changes were assessed. Results: The CB rIPC group achieved higher bypass flow rates (p < .001). After CB start, both study groups developed significant decreases in PaO Conclusion: Although rIPC allowed increased blood flow during fetal CB and decreased IL-1 and TXA2 levels and placental VCAM-1, it did not prevent placental dysfunction in fetal lambs undergoing CB. (© 2022 Wiley Periodicals LLC.) |
References: | Sabik JF, Assad RS, Hanley FL. Halothane as an anesthetic for fetal surgery. J Pediatr Surg. 1993;28(4):542-546. Sabik JF, Assad RS, Hanley FL. Prostaglandin synthesis inhibition prevents placental dysfunction after fetal cardiac bypass. J Thorac Cardiovasc Surg. 1992;103(4):733-741. Sabik JF, Heinemann MK, Assad RS, Hanley FL. High-dose steroids prevent placental dysfunction after fetal cardiac bypass. J Thorac Cardiovasc Surg. 1994;107(1):116-124. Cheung MM, Kharbanda RK, Konstantinov IE, et al. Randomized controlled trial of the effects of remote ischemic preconditioning on children undergoing cardiac surgery: first clinical application in humans. J Am Coll Cardiol. 2006;47:2277-2282. Costa JF, Fontes-Carvalho R, Leite-Moreira AF. Myocardial remote ischemic preconditioning: from pathophysiology to clinical application. Rev Port Cardiol. 2013;32(11):893-904. Fellahi JL, Gue X, Richomme X. Short- and long-term prognostic value of postoperative cardiac troponin I concentration in patients undergoing coronary artery bypass grafting. Anesthesiology. 2003;99:270-274. Hausenloy DJ, Mwamure PK, Venugopal V. Effect of remote ischaemic preconditioning on myocardial injury in patients undergoing coronary artery bypass graft surgery: a randomised controlled trial. Lancet. 2007;370:575-579. Lerut E, Kuypers DR, Verbeken E, Cleutjens J, Vlaminck H, Van Damme YVB. Acute rejection in non-compliant renal allograft recipients: a distinct morphology. Clin Transplant. 2007;21(3):344-351. Reddy VM, Liddicoat JR, Klein JR, McElhinney DB, Wampler RK, Hanley FL. Fetal cardiac bypass using an in-line axial flow pump to minimize extracorporeal surface and avoid priming volume. Ann Thorac Surg. 1996;62(2):393-400. Sebastian VA, Ferro G, Kagawa H, et al. Fetal cardiac intervention: improved results of fetal cardiac bypass in immature fetuses using the tiny pump device. J Thorac Cardiovasc Surg. 2013;145(6):1460-1464. Parry AJ, Petrossian E, McElhinney DB, Reddy VM, Hanley FL. Neutrophil degranulation and complement activation during fetal cardiac bypass. Ann Thorac Surg. 2000;70(2):582-589. Carotti A1, Emma F, Picca S, et al. Inflammatory response to cardiac bypass in ewe fetuses: effects of steroid administration or continuous hemodiafiltration. J Thorac Cardiovasc Surg. 2003;126(6):1839-1850. Zhou CB, Zhuang J, Chen JM, Zhang XH, Lui RC. Decrease in inflammatory response does not prevent placental dysfunction after fetal cardiac bypass in goats. J Thorac Cardiovasc Surg. 2012;143(2):445-450. Reddy VM, McElhinney DB, Rajasinghe HA, Rodriguez JL, Hanley FL. Cytokine response to fetal cardiac bypass. J Matern Fetal Investig. 1998;8(1):46-49. Weinbrenner C, Nelles M, Herzog N, Sárváry L, Strasser RH. Remote preconditioning by infrarenal occlusion of the aorta protects the heart from infarction: a newly identified non-neuronal but PKC-dependent pathway. Cardiovasc Res. 2002;55(3):590-601. Tota B, Quintieri AM, Angelone T. The emerging role of nitrite as an endogenous modulator and therapeutic agent of cardiovascular function. Curr Med Chem. 2010;17:1915-1925. Rassaf T, Totzeck M, Hendgen-Cotta UB, Shiva S, Heusch G, Kelm M. Circulating nitrite contributes to cardioprotection by remote ischemic preconditioning. Circ Res. 2014;114:1601-1610. Yellon DM, Downey JM. Preconditioning the myocardium: from cellular physiology to clinical cardiology. Physiol Rev. 2003;83:1113-1151. Ikai A, Riemer RK, Ramamoorthy C, et al. Preliminary results of fetal cardiac bypass in nonhuman primates. J Thorac Cardiovasc Surg. 2005;129(1):175-181. Kottenberg E, Musiolik J, Thielmann M, Jakob H, Peters J, Heusch G. Interference of propofol with signal transducer and activator of transcription 5 activation and cardioprotection by remote ischemic preconditioning during coronary artery bypass grafting. J Thorac Cardiovasc Surg. 2014;147(1):376-382. |
معلومات مُعتمدة: | FUNDACAO DE AMPARO A PESQUISA DO ESTADO DE SAO PAULO |
فهرسة مساهمة: | Keywords: fetal cardiac bypass; inflammation; ischemia-reperfusion; ischemic preconditioning; placenta |
المشرفين على المادة: | 0 (Interleukin-1) 0 (Vascular Cell Adhesion Molecule-1) |
تواريخ الأحداث: | Date Created: 20220701 Date Completed: 20220803 Latest Revision: 20220803 |
رمز التحديث: | 20240829 |
DOI: | 10.1111/jocs.16718 |
PMID: | 35775747 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1540-8191 |
---|---|
DOI: | 10.1111/jocs.16718 |