دورية أكاديمية
Chemical constituents of Antidesma bunius aerial parts and the anti-AGEs activity of selected compounds.
العنوان: | Chemical constituents of Antidesma bunius aerial parts and the anti-AGEs activity of selected compounds. |
---|---|
المؤلفون: | Nguyen-Ngoc H; Institute of Pharmacy, Pharmacognosy, Center for Molecular Biosciences (CMBI), University of Innsbruck, Innrain 80-82/IV, 6020, Innsbruck, Austria; Faculty of Pharmacy, PHENIKAA University, Hanoi, 12116, Viet Nam., Alilou M; Institute of Pharmacy, Pharmacognosy, Center for Molecular Biosciences (CMBI), University of Innsbruck, Innrain 80-82/IV, 6020, Innsbruck, Austria., Derbré S; SONAS, EA921, UNIV Angers, SFR QUASAV, Faculty of Health Sciences, Dpt Pharmacy, 16 Bd Daviers, 49045, Angers cedex 01, France., Blanchard P; SONAS, EA921, UNIV Angers, SFR QUASAV, Faculty of Health Sciences, Dpt Pharmacy, 16 Bd Daviers, 49045, Angers cedex 01, France., Pham GN; College of Pharmacy, Chungnam National University, Daejeon, 34134, Republic of Korea., Nghiem DT; Department of Botany, Hanoi University of Pharmacy, 13-15 Le Thanh Tong, Hoan Kiem, Hanoi, 10000, Viet Nam., Richomme P; SONAS, EA921, UNIV Angers, SFR QUASAV, Faculty of Health Sciences, Dpt Pharmacy, 16 Bd Daviers, 49045, Angers cedex 01, France., Stuppner H; Institute of Pharmacy, Pharmacognosy, Center for Molecular Biosciences (CMBI), University of Innsbruck, Innrain 80-82/IV, 6020, Innsbruck, Austria., Ganzera M; Institute of Pharmacy, Pharmacognosy, Center for Molecular Biosciences (CMBI), University of Innsbruck, Innrain 80-82/IV, 6020, Innsbruck, Austria. Electronic address: markus.ganzera@uibk.ac.at. |
المصدر: | Phytochemistry [Phytochemistry] 2022 Oct; Vol. 202, pp. 113300. Date of Electronic Publication: 2022 Jul 05. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Elsevier Country of Publication: England NLM ID: 0151434 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3700 (Electronic) Linking ISSN: 00319422 NLM ISO Abbreviation: Phytochemistry Subsets: MEDLINE |
أسماء مطبوعة: | Publication: 2003- : London : Elsevier Original Publication: 1961-2003: Oxford : Pergamon Press. |
مواضيع طبية MeSH: | Biological Products* , Euphorbiaceae*/chemistry, Glycation End Products, Advanced ; Plant Components, Aerial ; Vietnam |
مستخلص: | Thirty-three natural products were isolated from the aerial parts of Antidesma bunius, Euphorbiaceae, a plant used in Vietnamese traditional medicine against rheumatoid arthritis. All compounds were reported the first time for this species, and nine constituents resembled undescribed natural products, noticeably three coumarinolignans with 2,2-dimethyl-1,3-dioxolane moiety, two cyclopeptides, and two furofuran-type lignans connected with a phenylpropanoid moiety. The individual structures were elucidated by combining NMR and MS data, and their configuration was established by NOESY and ECD experiments and NMR calculations. Compounds with sufficient amount were analyzed for their inhibition of advanced glycation endproducts (AGEs) formation, metabolites involved in many diseases like Alzheimer, joint diseases or diabetes. With IC (Copyright © 2022 The Authors. Published by Elsevier Ltd.. All rights reserved.) |
فهرسة مساهمة: | Keywords: Advanced glycation endproducts; Antidesma bunius; Coumarinolignan; Cyclopeptide; Euphorbiaceae |
المشرفين على المادة: | 0 (Biological Products) 0 (Glycation End Products, Advanced) |
تواريخ الأحداث: | Date Created: 20220707 Date Completed: 20220907 Latest Revision: 20220907 |
رمز التحديث: | 20221213 |
DOI: | 10.1016/j.phytochem.2022.113300 |
PMID: | 35798090 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1873-3700 |
---|---|
DOI: | 10.1016/j.phytochem.2022.113300 |