دورية أكاديمية
Abnormal Functional Connectivity Between Cerebral Hemispheres in Patients With High Myopia: A Resting FMRI Study Based on Voxel-Mirrored Homotopic Connectivity.
العنوان: | Abnormal Functional Connectivity Between Cerebral Hemispheres in Patients With High Myopia: A Resting FMRI Study Based on Voxel-Mirrored Homotopic Connectivity. |
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المؤلفون: | Cheng Y; Department of Ophthalmology, The First Affiliated Hospital of Nanchang University, Nanchang, China., Chen XL; Department of Ophthalmology, The First Affiliated Hospital of Nanchang University, Nanchang, China., Shi L; Department of Ophthalmology, The First Affiliated Hospital of Nanchang University, Nanchang, China., Li SY; Department of Ophthalmology, The First Affiliated Hospital of Nanchang University, Nanchang, China., Huang H; Department of Ophthalmology, The First Affiliated Hospital of Nanchang University, Nanchang, China., Zhong PP; Department of Ophthalmology, The First Affiliated Hospital of Nanchang University, Nanchang, China., Wu XR; Department of Ophthalmology, The First Affiliated Hospital of Nanchang University, Nanchang, China. |
المصدر: | Frontiers in human neuroscience [Front Hum Neurosci] 2022 Jun 23; Vol. 16, pp. 910846. Date of Electronic Publication: 2022 Jun 23 (Print Publication: 2022). |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101477954 Publication Model: eCollection Cited Medium: Print ISSN: 1662-5161 (Print) Linking ISSN: 16625161 NLM ISO Abbreviation: Front Hum Neurosci Subsets: PubMed not MEDLINE |
أسماء مطبوعة: | Original Publication: Lausanne, Switzerland : Frontiers Research Foundation, 2008- |
مستخلص: | Purpose: To study the changes in functional connections between the left and right hemispheres of patients with high myopia (HM) and healthy controls (HCs) by resting functional magnetic resonance imaging (fMRI) based on voxel-mirrored homotopic connectivity (VMHC). To study the changes in resting-state functional connectivity (rsFC) between the left and right hemispheres of patients with HM and healthy controls (HCS) at rest by using resting functional magnetic resonance imaging (fMRI) based on voxel-mirror homotopy connectivity (VMHC). Patients and Methods: A total of 89 patients with HM (41 men and 48 women) and 59 HCs (24 men and 35 women) were collected and matched according to gender, age, and education level. The VMHC method was used to evaluate the changes in rsFC between cerebral hemispheres, and a correlation analysis was carried out to understand the differences in brain functional activities between the patients with HM and the HCs. Results: Compared with the HCs, the VMHC values of the putamen and fusiform in the HM group were significantly lower (voxel-level p < 0.01, Gaussian random field correction cluster level p < 0.05). Conclusion: This study preliminarily confirmed the destruction of interhemispheric functional connection in some brain regions of the patients with HM and provided effective information for clarifying the neural mechanism of patients with HM. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2022 Cheng, Chen, Shi, Li, Huang, Zhong and Wu.) |
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فهرسة مساهمة: | Keywords: functional magnetic resonance imaging; fusiform gyrus; high myopia; putamen; voxel-mirrored homotopic connectivity |
تواريخ الأحداث: | Date Created: 20220711 Latest Revision: 20220716 |
رمز التحديث: | 20221213 |
مُعرف محوري في PubMed: | PMC9259881 |
DOI: | 10.3389/fnhum.2022.910846 |
PMID: | 35814958 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1662-5161 |
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DOI: | 10.3389/fnhum.2022.910846 |