دورية أكاديمية
Prebiotic effects of plant-derived (poly)phenols on host metabolism: Is there a role for short-chain fatty acids?
| العنوان: | Prebiotic effects of plant-derived (poly)phenols on host metabolism: Is there a role for short-chain fatty acids? |
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| المؤلفون: | Freitas PL; Laboratory of Experimental Physiology (LeFisio), Department of Physiological Sciences, Biological and Health Sciences Center, Federal University of Maranhão, São Luís, Brazil.; Health Sciences Graduate Program, Biological and Health Sciences Center, Federal University of Maranhão, São Luís, Brazil., Barros MVC; Laboratory of Experimental Physiology (LeFisio), Department of Physiological Sciences, Biological and Health Sciences Center, Federal University of Maranhão, São Luís, Brazil., Fróes RBL; Laboratory of Experimental Physiology (LeFisio), Department of Physiological Sciences, Biological and Health Sciences Center, Federal University of Maranhão, São Luís, Brazil., França LM; Laboratory of Experimental Physiology (LeFisio), Department of Physiological Sciences, Biological and Health Sciences Center, Federal University of Maranhão, São Luís, Brazil.; Health Sciences Graduate Program, Biological and Health Sciences Center, Federal University of Maranhão, São Luís, Brazil., Paes AMA; Laboratory of Experimental Physiology (LeFisio), Department of Physiological Sciences, Biological and Health Sciences Center, Federal University of Maranhão, São Luís, Brazil.; Health Sciences Graduate Program, Biological and Health Sciences Center, Federal University of Maranhão, São Luís, Brazil. |
| المصدر: | Critical reviews in food science and nutrition [Crit Rev Food Sci Nutr] 2023 Nov; Vol. 63 (33), pp. 12285-12293. Date of Electronic Publication: 2022 Jul 14. |
| نوع المنشور: | Review; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Taylor & Francis Group Country of Publication: United States NLM ID: 8914818 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-7852 (Electronic) Linking ISSN: 10408398 NLM ISO Abbreviation: Crit Rev Food Sci Nutr Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Philadelphia, PA : Taylor & Francis Group Original Publication: Boca Raton, Fla. : CRC Press, c1980- |
| مواضيع طبية MeSH: | Diabetes Mellitus, Type 2*/prevention & control , Gastrointestinal Microbiome*, Humans ; Prebiotics ; Phenols/pharmacology ; Fatty Acids, Volatile/metabolism |
| مستخلص: | The gut microbiota has been extensively investigated during the last decade because of its effects on host neuroendocrine pathways and other processes. The imbalance between beneficial and pathogenic bacteria, known as dysbiosis, may be a determining predisposing factor for many noncommunicable chronic diseases, such as obesity, type 2 diabetes mellitus, metabolic syndrome, and Alzheimer's disease. On the other hand, interventions aiming to reestablish the balance between microbiota components have been suggested as potential preventive therapeutic strategies against these disorders. Among these interventions, dietary supplementation with (poly)phenols has been highlighted due to the modulatory effects exerted by those compounds on the gut microbiota. In addition, (poly)phenol consumption is associated with increased production of short-chain fatty acids (SCFAs), a set of microbial metabolites whose actions are ascribed to improving the abovementioned metabolic disorders. Thus, this review discusses the modulation of the gut microbiota by prebiotic (poly)phenols based on in vivo studies performed with isolated (poly)phenolic compounds, their interaction with the gut microbiota and the production of SCFAs in pursuit of the molecular mechanisms underlying the health effects of (poly)phenols on host metabolism. |
| فهرسة مساهمة: | Keywords: (poly)phenols; Gut microbiota; prebiotics; short-chain fatty acids |
| المشرفين على المادة: | 0 (Prebiotics) 0 (Phenols) 0 (Fatty Acids, Volatile) |
| تواريخ الأحداث: | Date Created: 20220714 Date Completed: 20231222 Latest Revision: 20231222 |
| رمز التحديث: | 20231222 |
| DOI: | 10.1080/10408398.2022.2100315 |
| PMID: | 35833476 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1549-7852 |
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| DOI: | 10.1080/10408398.2022.2100315 |