دورية أكاديمية
Assessment of depression in children and adolescents with sickle cell anemia in a low-resource setting: a comparative study.
| العنوان: | Assessment of depression in children and adolescents with sickle cell anemia in a low-resource setting: a comparative study. |
|---|---|
| المؤلفون: | Ezenwosu OU; Department of Paediatrics, Faculty of Medical Sciences, College of Medicine, University of Nigeria, Enugu, Nigeria.; Institute of Maternal and Child Health, University of Nigeria, Enugu, Nigeria.; University of Nigeria, Centre for Translational and Implementation Research, Enugu, Nigeria., Chukwu BF; Department of Paediatrics, Faculty of Medical Sciences, College of Medicine, University of Nigeria, Enugu, Nigeria., Uwaezuoke NA; Department of Paediatrics, Faculty of Medical Sciences, College of Medicine, University of Nigeria, Enugu, Nigeria., Ezenwosu IL; Department of Community Medicine, University of Nigeria Teaching Hospital, Enugu, Nigeria., Urom KO; Department of Paediatrics, Faculty of Medical Sciences, College of Medicine, University of Nigeria, Enugu, Nigeria., Udorah MI; Annunciation Specialist Hospital, Emene, Enugu., Ikefuna AN; Department of Paediatrics, Faculty of Medical Sciences, College of Medicine, University of Nigeria, Enugu, Nigeria., Emodi IJ; Department of Paediatrics, Faculty of Medical Sciences, College of Medicine, University of Nigeria, Enugu, Nigeria. |
| المصدر: | Pediatric hematology and oncology [Pediatr Hematol Oncol] 2023 Feb; Vol. 40 (1), pp. 40-50. Date of Electronic Publication: 2022 Jul 15. |
| نوع المنشور: | Observational Study; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Informa Healthcare Country of Publication: England NLM ID: 8700164 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-0669 (Electronic) Linking ISSN: 08880018 NLM ISO Abbreviation: Pediatr Hematol Oncol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2006- : London : Informa Healthcare Original Publication: Washington, DC : Hemisphere Pub. Corp., c1986- |
| مواضيع طبية MeSH: | Depression*/epidemiology , Depression*/etiology , Anemia, Sickle Cell*/complications , Anemia, Sickle Cell*/epidemiology , Anemia, Sickle Cell*/psychology, Humans ; Child ; Adolescent ; Cross-Sectional Studies ; Prevalence ; Case-Control Studies |
| مستخلص: | Children with sickle cell anemia (SCA) usually face psychological complications especially depression. Assessment of depression in resource-limited settings may help identify the extent to which the children with SCA in such settings may need its introduction as part of routine care. This study aimed to assess depression in children and adolescents with SCA in a low-resource setting. This cross-sectional observational study involved 84 children and adolescents with SCA aged 7-17 years who were selected using a systematic random sampling technique. Their controls were 84 age- and sex-matched individuals with AA hemoglobin genotype. A structured questionnaire was used to collect socio-demographic data while depression was assessed with the Children's Depression Inventory. The prevalence of depression was non-significantly higher in subjects compared to the controls (8.3% vs. 2.4%) (Fisher's χ 2 = 1.88, p = 0.171). Though not statistically significant, the subjects had 3.7 times higher odds of having depression compared to the controls (OR = 3.7; 95% CI 0.75-18.50; p = 0.107). Of the 5 depression subscales, the subjects had a significantly higher difference in the negative mood ( p = 0.042). Despite the comparable prevalence of depression with their normal controls, children and adolescents with SCA had a higher negative mood and higher odds of having depression than normal individuals. Thus, there is a need for the introduction of depression assessment as a complement to routine care of these children with SCA in resource-poor settings. |
| فهرسة مساهمة: | Keywords: Adolescents; children; depression; low-resource; sickle cell |
| تواريخ الأحداث: | Date Created: 20220715 Date Completed: 20230130 Latest Revision: 20230202 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1080/08880018.2022.2071510 |
| PMID: | 35838017 |
| قاعدة البيانات: | MEDLINE |
PDF full text from Publisher | تدمد: | 1521-0669 |
|---|---|
| DOI: | 10.1080/08880018.2022.2071510 |