دورية أكاديمية
Fucoidan-based nanoparticles: Preparations and applications.
العنوان: | Fucoidan-based nanoparticles: Preparations and applications. |
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المؤلفون: | Venkatesan J; Department of Bionano Engineering, Center for Bionano Intelligence Education and Research, Hanyang University, ERICA, Ansan 426-791, South Korea; Biomaterials Research Laboratory, Yenepoya Research Centre, Yenepoya (Deemed to be University), Deralakatte, Mangaluru 575018, India., Murugan SS; Biomaterials Research Laboratory, Yenepoya Research Centre, Yenepoya (Deemed to be University), Deralakatte, Mangaluru 575018, India., Seong GH; Department of Bionano Engineering, Center for Bionano Intelligence Education and Research, Hanyang University, ERICA, Ansan 426-791, South Korea. Electronic address: ghseong@hanyang.ac.kr. |
المصدر: | International journal of biological macromolecules [Int J Biol Macromol] 2022 Sep 30; Vol. 217, pp. 652-667. Date of Electronic Publication: 2022 Jul 13. |
نوع المنشور: | Journal Article; Review |
اللغة: | English |
بيانات الدورية: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE |
أسماء مطبوعة: | Publication: Amsterdam : Elsevier Original Publication: Guildford, Eng., IPC Science and Technology Press. |
مواضيع طبية MeSH: | Metal Nanoparticles* , Nanoparticles* , Neoplasms*/drug therapy, Drug Delivery Systems ; Humans ; Polysaccharides/therapeutic use |
مستخلص: | Nanoparticle-based therapy has gained much attention in the pharmaceutical industry. Fucoidan is a sulfated polysaccharide naturally derived from marine brown algae and is widely used for medical applications. We explore preparation of fucoidan-based nanoparticles and their biomedical applications in the current review. The fucoidan-based nanoparticles have been synthesized using microwave, emulsion, solvent evaporation, green synthesis, polyelectrolyte self-assembly, precipitation, and ultrasonication methods. The synthesized nanoparticles have particle sizes ranging from 100 to 400 nm. Therefore, fucoidan-based nanoparticles have a variety of potential therapeutic applications, including drug delivery, cancer therapies, tissue engineering, antimicrobial applications, magnetic resonance imaging contrast, and atherothrombosis imaging. For example, fucoidan nanoparticles have been used to deliver curcumin, dextran, gentamicin, epigallocatechin gallate, and cisplatin for cancer therapies. Furthermore, fucoidan nanoparticles coupled with metal nanoparticles have been used to target and recognize clinical conditions for diagnostic purposes. Hence, fucoidan-based nanoparticles have been helpful for biomedical applications. (Copyright © 2022 Elsevier B.V. All rights reserved.) |
فهرسة مساهمة: | Keywords: Cancer therapies; Drug delivery; Fucoidan; Magnetic resonance imaging contrast agent; Tissue engineering |
المشرفين على المادة: | 0 (Polysaccharides) 9072-19-9 (fucoidan) |
تواريخ الأحداث: | Date Created: 20220716 Date Completed: 20220901 Latest Revision: 20220906 |
رمز التحديث: | 20221213 |
DOI: | 10.1016/j.ijbiomac.2022.07.068 |
PMID: | 35841962 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1879-0003 |
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DOI: | 10.1016/j.ijbiomac.2022.07.068 |