دورية أكاديمية
Cancer clinical trials in the Philippines.
العنوان: | Cancer clinical trials in the Philippines. |
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المؤلفون: | Eala MAB; College of Medicine, University of the Philippines, 547 Pedro Gil Street, 1000, Manila, Philippines. mbeala1@up.edu.ph., Basilio PAS; College of Medicine, University of the Philippines, 547 Pedro Gil Street, 1000, Manila, Philippines., Dee EC; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Cereno REP; Department of Radiation Oncology, British Columbia Cancer Agency, Kelowna, BC, Canada., Ang CD; Department of Surgical Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Surgery, University of Santo Tomas Faculty of Medicine and Surgery, Manila, Philippines., Magsanoc NJ; Division of Urology, Department of Surgery, Philippine General Hospital, Manila, Philippines., Ting FIL; Section of Medical Oncology, Department of Internal Medicine, Dr. Pablo O. Torre Memorial Hospital, Bacolod, Philippines., Sacdalan DL; Division of Medical Oncology, Department of Internal Medicine, Philippine General Hospital, Manila, Philippines. |
المصدر: | Cancer causes & control : CCC [Cancer Causes Control] 2022 Oct; Vol. 33 (10), pp. 1273-1275. Date of Electronic Publication: 2022 Jul 20. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Kluwer Academic Publishers Country of Publication: Netherlands NLM ID: 9100846 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-7225 (Electronic) Linking ISSN: 09575243 NLM ISO Abbreviation: Cancer Causes Control Subsets: MEDLINE |
أسماء مطبوعة: | Publication: Dordrecht : Kluwer Academic Publishers Original Publication: Oxford, UK : Rapid Communications of Oxford Ltd., 1990- |
مواضيع طبية MeSH: | Income* , Neoplasms*/therapy, Asia, Southeastern ; Clinical Trials as Topic ; Developing Countries ; Humans ; Philippines/epidemiology |
مستخلص: | In this Commentary, we discuss disparities in resources for and access to cancer trials from the perspective of the Philippines, a lower-middle-income country in Southeast Asia, where cancer is the fourth leading cause of death. Geographic disparities play out such that academic institutions and clinical trials are centralized in the island of Luzon, particularly in the capital, Manila. These disparities are compounded by the lack of comprehensive cancer patient and clinical trial registries in the Philippines. Additionally, sociocultural considerations influence clinical trial implementation. Providers must consider the role of a patient's family in the decision to participate in clinical trials; a patient's degree of health literacy; and the economic burden of cancer care, with attention to both the direct and indirect financial toxicities associated with cancer care. Our call to action is threefold. (1) Bolster locally led trials and encourage international collaboration to improve diversity in trial participation and trials' generalizability. (2) Strengthen national trial registries to improve awareness of trials for which patients are eligible. (3) Integrate cultural competency frameworks that move beyond parachutism and parasitism in research and instead promote trust, reciprocity, and collaboration. These challenges may yet evolve, but in emphasizing these barriers, we hope to kindle further dialogue, new insights, and innovative action towards solving these disparities in cancer research, not just in the Philippines, but also in other low- and middle-income countries. (© 2022. The Author(s), under exclusive licence to Springer Nature Switzerland AG.) |
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فهرسة مساهمة: | Keywords: Cancer; Clinical trial; Philippines |
تواريخ الأحداث: | Date Created: 20220720 Date Completed: 20220901 Latest Revision: 20220906 |
رمز التحديث: | 20240628 |
DOI: | 10.1007/s10552-022-01611-9 |
PMID: | 35857181 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1573-7225 |
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DOI: | 10.1007/s10552-022-01611-9 |