دورية أكاديمية
أعرض في EDS

Routine Decontamination of Surfaces Relevant to Working Dogs: Neutralization of Superficial Coronavirus Contamination.

التفاصيل البيبلوغرافية
العنوان: Routine Decontamination of Surfaces Relevant to Working Dogs: Neutralization of Superficial Coronavirus Contamination.
المؤلفون: Grady SL; Applied Physics Laboratory, Johns Hopkins University, Laurel, MD 20723, USA., Sebeck NM; Applied Physics Laboratory, Johns Hopkins University, Laurel, MD 20723, USA., Theodore M; Applied Physics Laboratory, Johns Hopkins University, Laurel, MD 20723, USA., Meidenbauer KL; Applied Physics Laboratory, Johns Hopkins University, Laurel, MD 20723, USA.
المصدر: Animals : an open access journal from MDPI [Animals (Basel)] 2022 Jul 17; Vol. 12 (14). Date of Electronic Publication: 2022 Jul 17.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Molecular Diversity Preservation International Country of Publication: Switzerland NLM ID: 101635614 Publication Model: Electronic Cited Medium: Print ISSN: 2076-2615 (Print) Linking ISSN: 20762615 NLM ISO Abbreviation: Animals (Basel) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : Molecular Diversity Preservation International, 2011-
مستخلص: Given the increased deployment of working dogs to settings with pathogenic biological agents, a safe, effective, and logistically feasible surface decontamination protocol is essential to protect both the animals and their human handlers. Our group previously found that superficial contamination on surfaces relevant to the working dog community, including leashes and toys, could be significantly reduced using a standardized wiping protocol with various cleansing products. To expand upon this work, we analyzed the ability of this protocol to decontaminate surface-deposited bovine coronavirus, which was used as a BSL2 surrogate for SARS-CoV-2. Unsurprisingly, the physical characteristics of a given surface, including porosity and texture, had a significant effect on the ability to recover viable virus remaining on the surface post treatment. After correcting for these differences, however, wiping with 70% isopropyl alcohol (IPA) and 0.5% chlorhexidine performed best, reducing viral titers by >3 log on plastic bumper toys and nylon collars, and by >2 log on rubber toys and tennis balls. Leather leashes and Velcro proved more difficult to decontaminate, but both still showed significant loss of viral contamination following wiping with IPA or chlorhexidine. This work (i) validates the utility of a simple protocol for the neutralization of viruses on several surfaces, (ii) identifies materials that are more difficult to decontaminate, which should, thus, be considered for removal from field use, and (iii) highlights the need for further development of protocols testing porous or textured surfaces.
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معلومات مُعتمدة: 70RSAT19CB0000002 Department of Homeland Security Science and Technology (S&T) Directorate
فهرسة مساهمة: Keywords: biological hazards; coronavirus; surface decontamination; virus neutralization; working dogs
تواريخ الأحداث: Date Created: 20220727 Latest Revision: 20230308
رمز التحديث: 20230309
مُعرف محوري في PubMed: PMC9312250
DOI: 10.3390/ani12141823
PMID: 35883369
قاعدة البيانات: MEDLINE
الوصف
تدمد:2076-2615
DOI:10.3390/ani12141823