دورية أكاديمية
أعرض في EDS

Does Kidney Transplantation Help Young Patients on Dialysis With Erectile Dysfunction? A Single-center Study.

التفاصيل البيبلوغرافية
العنوان: Does Kidney Transplantation Help Young Patients on Dialysis With Erectile Dysfunction? A Single-center Study.
المؤلفون: El Hennawy HM; Surgery Department, Section of Transplantation, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia. Electronic address: hennawyhany@hotmail.com., Safar O; Urology Department, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia., Faifi ASA; Surgery Department, Section of Transplantation, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia., Shalkamy O; Urology Department, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia; Urology Department, Faculty of Medicine, Al Azhar University, Cairo, Egypt., Alqahtani Y; Urology Department, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia., Nazer WE; Nephrology Department, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia., Mahedy A; Nephrology Department, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia., Ali MA; Nephrology Department, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia., Atta EA; Surgery Department, Section of Transplantation, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia., Abdelaziz AA; Nephrology Department, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia., Malki AA; Nephrology Department, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia., Mirza N; Nephrology Department, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia., Fageeh AA; Nephrology Department, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia., Zaitoun MF; Pharmacy Department, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia., Elatreisy A; Urology Department, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia; Urology Department, Faculty of Medicine, Al Azhar University, Cairo, Egypt.
المصدر: Urology [Urology] 2022 Nov; Vol. 169, pp. 120-124. Date of Electronic Publication: 2022 Aug 06.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Science Country of Publication: United States NLM ID: 0366151 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-9995 (Electronic) Linking ISSN: 00904295 NLM ISO Abbreviation: Urology Subsets: MEDLINE
أسماء مطبوعة: Publication: New York : Elsevier Science
Original Publication: Ridgewood, N.J., Professional Medical Services Co.
مواضيع طبية MeSH: Erectile Dysfunction*/etiology , Kidney Transplantation* , Kidney Failure, Chronic*/complications , Kidney Failure, Chronic*/surgery, Humans ; Male ; Adult ; Middle Aged ; Renal Dialysis ; Prospective Studies ; Cross-Sectional Studies ; Penile Erection ; Surveys and Questionnaires
مستخلص: Objective: to investigate the effects of a successful KT on EF in male patients with ESRD.
Materials and Methods: A single-center cross-sectional prospective study to assess the erectile dysfunction in male patients one month before and one year after KT. We adopted a validated, self-administered translated International Index of Erectile Function (IIEF-15) questionnaire. A sub-analysis was performed by categorizing the cohort into 2 age groups: <50 and ≥50 yr.
Results: Between September 2017 and February 2021, 68 ESRD patients underwent kidney transplantation (KT), with a mean age of 48.9 ± 12.9 years. Thirty-one patients were below 50 years (Group I). The median hemodialysis duration was 12 months. Sixty-three patients (92.6%) had ED. The mean total IIEF-15 score before and after was 46.8/75 ±12.7 and 55.5 ±13, respectively (P <.001). Forty-six patients (67.6%) reported improved erectile function, 22 (32.4%) did not demonstrate any change, and no patient reported deterioration. Moreover, after KT, sexual desire, orgasm, and overall patient satisfaction improved significantly. Before KT, 83.8% and 100% of groups I and II patients had ED, which dropped to 22.6% and 86.5%, respectively, after KT. IIEF-15 scores improved in both groups. However, the improvement in ED was observed significantly in young patients with mild ED.
Conclusion: KT positively impacts sexual function and improves erectile dysfunction, especially among young patients. The duration of dialysis before kidney transplantation had no impact on ED improvement after transplantation. The positive effect of transplantation on ED could encourage ESRD patients to undergo KT.
(Copyright © 2022 Elsevier Inc. All rights reserved.)
تواريخ الأحداث: Date Created: 20220809 Date Completed: 20221115 Latest Revision: 20221202
رمز التحديث: 20221203
DOI: 10.1016/j.urology.2022.07.042
PMID: 35944654
قاعدة البيانات: MEDLINE
الوصف
تدمد:1527-9995
DOI:10.1016/j.urology.2022.07.042