دورية أكاديمية
أعرض في EDS

Chronic Disease Comorbidities Among Injured Patients in Cameroon: A Retrospective Cohort Study.

التفاصيل البيبلوغرافية
العنوان: Chronic Disease Comorbidities Among Injured Patients in Cameroon: A Retrospective Cohort Study.
المؤلفون: Blair KJ; Program for the Advancement of Surgical Equity, Department of Surgery, University of California Los Angeles, Los Angeles, California. Electronic address: kevin.james.blair@gmail.com., Dissak-Delon FN; Program for the Advancement of Surgical Equity, Department of Surgery, University of California Los Angeles, Los Angeles, California; Littoral Regional Delegation, Ministry of Public Health, Douala, Cameroon., Oke R; Program for the Advancement of Surgical Equity, Department of Surgery, University of California Los Angeles, Los Angeles, California., Carvalho M; Program for the Advancement of Surgical Equity, Department of Surgery, University of California Los Angeles, Los Angeles, California., Hubbard A; Division of Biostatistics, School of Public Health, University of California Berkeley, Berkeley, California., Mbianyor M; Program for the Advancement of Surgical Equity, Department of Surgery, University of California Los Angeles, Los Angeles, California., Etoundi-Mballa GA; Department of Disease Epidemic and Pandemic Control, Ministry of Public Health, Yaoundé, Cameroon., Kinge T; Hospital Administration, The Limbe Regional Hospital, Limbe, Cameroon., Njock LR; Hospital Administration, The Laquintinie Hospital of Douala, Douala, Cameroon., Nkusu DN; Hospital Administration, The Catholic Hospital of Pouma, Pouma, Cameroon., Tsiagadigui JG; Hospital Administration, The Edea Regional Hospital, Edea, Cameroon., Dicker RA; Program for the Advancement of Surgical Equity, Department of Surgery, University of California Los Angeles, Los Angeles, California., Chichom-Mefire A; Program for the Advancement of Surgical Equity, Department of Surgery, University of California Los Angeles, Los Angeles, California; Faculty of Health Sciences, University of Buea, Buea, Cameroon., Juillard C; Program for the Advancement of Surgical Equity, Department of Surgery, University of California Los Angeles, Los Angeles, California., Christie SA; Program for the Advancement of Surgical Equity, Department of Surgery, University of California Los Angeles, Los Angeles, California; Division of General and Trauma Surgery, Department of Surgery, University of Pittsburgh Medical Center, Pittsburg, Pennsylvania.
المصدر: The Journal of surgical research [J Surg Res] 2022 Dec; Vol. 280, pp. 74-84. Date of Electronic Publication: 2022 Aug 11.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 0376340 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-8673 (Electronic) Linking ISSN: 00224804 NLM ISO Abbreviation: J Surg Res Subsets: MEDLINE
أسماء مطبوعة: Publication: New York, NY : Academic Press
Original Publication: Philadelphia [etc.]
مواضيع طبية MeSH: Trauma Centers*, Humans ; Cameroon/epidemiology ; Retrospective Studies ; Injury Severity Score ; Chronic Disease
مستخلص: Introduction: Chronic diseases are increasing but underdiagnosed in low-income and middle-income countries (LMICs), where injury mortality is already disproportionately high. We estimated prevalence of known chronic disease comorbidities and their association with outcomes among injured patients in Cameroon.
Materials and Methods: Injured patients aged ≥15 y presenting to four Cameroonian hospitals between October 2017 and January 2020 were included. Our explanatory variable was known chronic disease; prevalence was age-standardized. Outcomes were overall in-hospital mortality and admission or transfer from the emergency department (ED). Associations between known chronic disease and outcomes were evaluated using logistic regression adjusted for age, gender, estimated injury severity score (eISS), hospital, and household socioeconomic status. Unadjusted eISS-stratified and age-stratified outcomes were also compared via chi-squared tests.
Results: Of 7509 injured patients, 370 (4.9%) reported at least one known chronic disease; age-standardized prevalence was 8.4% (95% confidence interval [CI] 7.5%-9.2%). Patients with known chronic disease had higher mortality (4.6% versus 1.5%, adjusted odds ratio [aOR]: 2.61 [95% CI: 1.25-5.47], P = 0.011) and were more likely to be admitted or transferred from the ED (38.7% versus 19.8%, aOR: 1.40 [95% CI: 1.02-1.92], P = 0.038) compared to those without known comorbidities. Crude differences in mortality (11.3% versus 3.3%, P = 0.002) and hospital admission or transfer (63.8% versus 46.6%, P = 0.011) were most notable for patients with eISS 16-24.
Conclusions: Despite underdiagnosis among Cameroonians, we demonstrated worse injury outcomes among those with known chronic diseases. Integrating chronic disease screening with injury care may help address underdiagnosis in Cameroon. Future work should assess whether chronic disease prevention in LMICs could improve injury outcomes.
(Copyright © 2022 Elsevier Inc. All rights reserved.)
فهرسة مساهمة: Keywords: Cameroon; Chronic disease; Comorbidity; Injury; Sub-Saharan Africa; Trauma
تواريخ الأحداث: Date Created: 20220814 Date Completed: 20221024 Latest Revision: 20221209
رمز التحديث: 20231215
DOI: 10.1016/j.jss.2022.06.045
PMID: 35964485
قاعدة البيانات: MEDLINE
الوصف
تدمد:1095-8673
DOI:10.1016/j.jss.2022.06.045