دورية أكاديمية
Breastfeeding on Injectable Opioid Agonist Therapy: A Case Report.
| العنوان: | Breastfeeding on Injectable Opioid Agonist Therapy: A Case Report. |
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| المؤلفون: | Patricelli CJ; From the Families in Recovery (FIR) Unit, BC Women's Hospital and Health Centre, Vancouver, BC, Canada (CJP, IJG, SGo, NC, VP, KS); Women's Health Research Institute, Vancouver, BC, Canada (CJP, IJG, SGo, AA, KS, SGe); Department of Family Practice, University of British Columbia, Vancouver, BC, Canada (CJP); Department of Obstetrics and Gynaecology, University of British Columbia, Vancouver, BC, Canada (AA); Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada (SGe); and Department of Public Health and Social Policy, University of Victoria, Victoria, BC, Canada (KU)., Gouin IJ, Gordon S, Carter N, Albert A, Paquette V, Stewart K, George S, Urbanoski K |
| المصدر: | Journal of addiction medicine [J Addict Med] 2023 Mar-Apr 01; Vol. 17 (2), pp. 222-226. Date of Electronic Publication: 2022 Aug 24. |
| نوع المنشور: | Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wolters Kluwer Health, Inc Country of Publication: Netherlands NLM ID: 101306759 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1935-3227 (Electronic) Linking ISSN: 19320620 NLM ISO Abbreviation: J Addict Med Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: [Alphen aan den Rijn, the Netherlands] : Wolters Kluwer Health, Inc. Original Publication: Hagerstown, MD : Lippincott Williams & Wilkins |
| مواضيع طبية MeSH: | Breast Feeding* , Opioid-Related Disorders*/drug therapy, Infant ; Infant, Newborn ; Pregnancy ; Female ; Humans ; Adult ; Analgesics, Opioid/therapeutic use ; Hydromorphone/therapeutic use ; Mothers |
| مستخلص: | Background: Injectable opioid agonist therapy (iOAT) is the highest-intensity treatment currently available in Canada for individuals with severe opioid use disorder. However, there is limited data on iOAT administration in the perinatal period, with no research, practice guidelines, or known reports of breastfeeding on iOAT. This article presents the first known case of an individual breastfeeding on iOAT. Case Summary: We present a case of a pregnant 32-year-old woman from Canada with severe opioid use disorder, who stabilized with iOAT and chose to breastfeed her infant. She presented to hospital at 38 + 6 gestation in labor, unstable in her substance use disorder despite multiple interventions and was initiated on iOAT (intravenous hydromorphone) shortly after delivery. Before initiation of breastfeeding the infant was admitted to the neonatal intensive care unit for monitoring. On day 9 of life the infant received breastmilk for the first time, and was discharged from neonatal intensive care unit on day 12 of life with no clinical evidence of sedation or respiratory depression. The infant maintained mixed feeding and at 58 days of life was discharged in the mother and father's care, a healthy infant with stable vitals. Discussion: This case suggests positive infant and maternal health and social outcomes for breastfeeding on iOAT. Further research on perinatal iOAT use and the pharmacokinetics of high-dose hydromorphone in breastmilk is required to inform clinical practice guidelines to safely support individuals and their infants who are impacted by substance use. Competing Interests: The authors report no conflicts of interest. (Copyright © 2022 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Society of Addiction Medicine.) |
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| المشرفين على المادة: | 0 (Analgesics, Opioid) Q812464R06 (Hydromorphone) |
| تواريخ الأحداث: | Date Created: 20220824 Date Completed: 20230316 Latest Revision: 20230401 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC10022656 |
| DOI: | 10.1097/ADM.0000000000001055 |
| PMID: | 36001061 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1935-3227 |
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| DOI: | 10.1097/ADM.0000000000001055 |