دورية أكاديمية
Eosinophilic Granulomatous Myocarditis in Two Pigs.
| العنوان: | Eosinophilic Granulomatous Myocarditis in Two Pigs. |
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| المؤلفون: | De Conti ER; Department of Veterinary Pathology, Federal University of Rio Grande do Sul, Porto Alegre, Brazil., Piva MM; Department of Veterinary Pathology, Federal University of Rio Grande do Sul, Porto Alegre, Brazil. Electronic address: manoela.marchezan@gmail.com., Bianchi RM; Department of Veterinary Pathology, Federal University of Rio Grande do Sul, Porto Alegre, Brazil., Schwertz CI; Department of Veterinary Pathology, Federal University of Rio Grande do Sul, Porto Alegre, Brazil., Henker LC; Department of Veterinary Pathology, Federal University of Rio Grande do Sul, Porto Alegre, Brazil., Lorenzett MP; Department of Veterinary Pathology, Federal University of Rio Grande do Sul, Porto Alegre, Brazil., Vannucci FA; Veterinary Diagnostic Laboratory, College of Veterinary Medicine, University of Minnesota, Saint Paul, Minnesota, USA., Pavarini SP; Department of Veterinary Pathology, Federal University of Rio Grande do Sul, Porto Alegre, Brazil. |
| المصدر: | Journal of comparative pathology [J Comp Pathol] 2022 Aug; Vol. 196, pp. 21-25. Date of Electronic Publication: 2022 Jul 06. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: England NLM ID: 0102444 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-3129 (Electronic) Linking ISSN: 00219975 NLM ISO Abbreviation: J Comp Pathol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: London : Elsevier Original Publication: Liverpool, University Press. |
| مواضيع طبية MeSH: | Circoviridae Infections*/veterinary , Circovirus* , Myocarditis*/complications , Myocarditis*/veterinary , Swine Diseases*/pathology, Animals ; DNA, Viral/analysis ; Humans ; In Situ Hybridization/veterinary ; Swine |
| مستخلص: | Eosinophilic myocarditis is a human condition that has been rarely documented in animals. We now report two unrelated porcine cases of idiopathic eosinophilic granulomatous myocarditis that resembled the human disease and which were associated with sudden death. The most relevant gross finding in both cases was marked cardiomegaly, accompanied by raised, multifocal to coalescent small white nodules (1-2 mm) and poorly demarcated multifocal pale areas in the epicardium. Histologically, there were multifocal to coalescent areas of cardiomyocyte loss with replacement by an intense inflammatory infiltrate of eosinophils and epithelioid macrophages, and proliferation of fibrous connective tissue. Immunohistochemistry for porcine circovirus type 2 (PCV2) and Toxoplasma gondii, in-situ hybridization and quantitative polymerase chain reaction tests for PCV2 and porcine circovirus type 3 and aerobic bacterial culture on myocardium samples were negative. Competing Interests: Conflict of Interest Statement The authors declared no potential conflicts of interest with respect to the research, authorship or publication of this article. (Copyright © 2022 Elsevier Ltd. All rights reserved.) |
| فهرسة مساهمة: | Keywords: eosinophilic myocarditis; heart fibrosis; sudden death; swine pathology |
| المشرفين على المادة: | 0 (DNA, Viral) |
| تواريخ الأحداث: | Date Created: 20220825 Date Completed: 20220829 Latest Revision: 20220829 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1016/j.jcpa.2022.05.005 |
| PMID: | 36008041 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1532-3129 |
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| DOI: | 10.1016/j.jcpa.2022.05.005 |