دورية أكاديمية
أعرض في EDS

Pediatric Off-Label COVID-19 Vaccination: The Concerns of Healthcare Professionals in Pakistan.

التفاصيل البيبلوغرافية
العنوان: Pediatric Off-Label COVID-19 Vaccination: The Concerns of Healthcare Professionals in Pakistan.
المؤلفون: Shakeel S; Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Dow College of Pharmacy, Dow University of Health Sciences, Karachi 74200, Pakistan., Nesar S; Jinnah College of Pharmacy, Sohail University, Karachi 74000, Pakistan., Nizami GN; Jinnah College of Rehabilitation Sciences, Sohail University, Karachi 74000, Pakistan., Iqbal Z; Jinnah College of Nursing, Sohail University, Karachi 74000, Pakistan., Emad S; Department of Biochemistry, Jinnah Medical & Dental College, Sohail University, Karachi 74000, Pakistan., Wasim Q; Department of Pharmacy Practice, Faculty of Pharmacy, Jinnah University for Women, Karachi 74600, Pakistan., Mumtaz T; Jinnah College of Pharmacy, Sohail University, Karachi 74000, Pakistan., Jamshed S; Department of Clinical Pharmacy and Practice, Faculty of Pharmacy, Universiti Sultan Zainal Abidin, UniSZA, Kuala Terengganu 21300, Malaysia., Usmani MS; Sindh Medical College, Jinnah Sindh Medical University, Karachi 75510, Pakistan., Hussain R; Discipline of Social and Administrative Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Pulau Pinang 11800, Malaysia.
المصدر: Vaccines [Vaccines (Basel)] 2022 Aug 02; Vol. 10 (8). Date of Electronic Publication: 2022 Aug 02.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101629355 Publication Model: Electronic Cited Medium: Print ISSN: 2076-393X (Print) Linking ISSN: 2076393X NLM ISO Abbreviation: Vaccines (Basel) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI AG
مستخلص: Global health authorities have emphasized the vital role of healthcare professionals (HCPs) as a reliable source of vaccination information for patients in primary care. However, HCPs are concerned whether COVID-19 vaccinations can be used off-label. Hence, the current study was conducted to assess their perspectives towards off-label COVID-19 immunization in children. The study tool, consisting of 40 items, was utilized to evaluate HCPs' knowledge and attitudes towards the off-label use of the COVID-19 vaccine in children under 12 years of age. To assess the unfavorable attitudes regarding vaccinations, the Vaccination Attitudes Examination Scale was employed. Overall, 477 completed questionnaires were incorporated in the present study, with a response rate of 88.9%. The mean age of the respondents was 38.6 ± 7.5 years; among whom the majority were physicians, n = 209 (43.8%), and pharmacists, n = 112 (23.4%). Approximately 78% of the respondents had a general awareness of off-label vaccination. Around 80% knew the adverse drug reactions associated with the use of COVID-19 vaccines. Females showed more mistrust about vaccine benefits, n = 55 (16.9%), compared to males, n = 21 (13.8%), and concerns about commercial profits of vaccines, n = 59 (18.1%), compared to males, n = 19 (12.5%). By profession, physicians showed statistically significantly lower mistrust, n = 18 (8.6%), and higher concerns about unpredicted effects of vaccines, n = 41 (19.6%). A major portion of the respondents, n = 327 (68.5%), did not consider that HCPs should prescribe/administer off-label COVID-19 vaccination in children. The current findings demonstrated that respondents had an appropriate level of understanding about COVID-19 immunization in children. They showed higher levels of rejection for off-label use of the COVID-19 vaccination.
References: Curr Opin Pediatr. 2021 Feb 1;33(1):144-151. (PMID: 33278108)
BMC Pediatr. 2018 Jul 25;18(1):242. (PMID: 30045715)
Vaccines (Basel). 2021 Sep 29;9(10):. (PMID: 34696210)
Lancet. 2021 May 1;397(10285):1646-1657. (PMID: 33901420)
Front Pediatr. 2020 Dec 10;8:613433. (PMID: 33363070)
Vaccines (Basel). 2021 May 17;9(5):. (PMID: 34067743)
Nature. 2020 Dec;588(7838):377-378. (PMID: 33311629)
Eur J Epidemiol. 2020 Aug;35(8):775-779. (PMID: 32785815)
Clin Infect Dis. 2021 Jul 15;73(2):336-340. (PMID: 32945335)
JAMA Pediatr. 2020 Apr 8;:. (PMID: 32267485)
J Korean Med Sci. 2021 Feb 22;36(7):e59. (PMID: 33619920)
Int J Gen Med. 2020 Jul 28;13:477-482. (PMID: 32848446)
Int J Clin Pract. 2021 Jul;75(7):e14226. (PMID: 33864328)
JAMA Pediatr. 2021 Feb 1;175(2):125-126. (PMID: 32926083)
BMC Pediatr. 2022 Jan 3;22(1):3. (PMID: 34980031)
MMWR Morb Mortal Wkly Rep. 2021 Dec 31;70(5152):1755-1760. (PMID: 34968370)
Lancet Infect Dis. 2021 Dec;21(12):1614-1615. (PMID: 34197765)
Ital J Pediatr. 2020 Apr 29;46(1):56. (PMID: 32349772)
J Community Health. 2021 Apr;46(2):270-277. (PMID: 33389421)
J Community Psychol. 2022 Mar;50(2):666-683. (PMID: 34217150)
Euro Surveill. 2021 Jan;26(3):. (PMID: 33478623)
Hastings Cent Rep. 2021 Nov;51(6):27-32. (PMID: 34750807)
Indian Pediatr. 2020 May 15;57(5):435-442. (PMID: 32273490)
JAMA. 2022 Jan 4;327(1):23-25. (PMID: 34910088)
Ann Behav Med. 2017 Oct;51(5):652-660. (PMID: 28255934)
Arch Dis Child. 2022 Mar;107(3):e1. (PMID: 34732388)
JAMA. 2021 Sep 28;326(12):1210-1212. (PMID: 34347001)
Children (Basel). 2021 Jul 18;8(7):. (PMID: 34356586)
Vaccines (Basel). 2021 Nov 09;9(11):. (PMID: 34835228)
J Infect Dev Ctries. 2020 Mar 31;14(3):254-264. (PMID: 32235085)
Vaccine. 2020 Oct 21;38(45):7146-7155. (PMID: 32943265)
فهرسة مساهمة: Keywords: COVID-19 vaccinations; Pakistan; healthcare professionals; off-label use
تواريخ الأحداث: Date Created: 20220826 Latest Revision: 20220830
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC9414769
DOI: 10.3390/vaccines10081236
PMID: 36016124
قاعدة البيانات: MEDLINE
الوصف
تدمد:2076-393X
DOI:10.3390/vaccines10081236