دورية أكاديمية
In vitro assessment of the acaricidal activity of a carvacrol shampoo on tick larvae.
| العنوان: | In vitro assessment of the acaricidal activity of a carvacrol shampoo on tick larvae. |
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| المؤلفون: | Sousa AP; Laboratory of Plant Biochemistry, Federal University of Maranhão, São Luís, MA, Brazil., Castro GS; Laboratory of Plant Biochemistry, Federal University of Maranhão, São Luís, MA, Brazil., Tavares CP; Laboratory of Parasite Control, Federal University of Maranhão, São Luís, MA, Brazil., Vale TLD; Laboratory of Parasite Control, Federal University of Maranhão, São Luís, MA, Brazil., Costa-Junior LM; Laboratory of Parasite Control, Federal University of Maranhão, São Luís, MA, Brazil. Electronic address: livio.martins@ufma.br., Soares AS; Laboratory of Plant Biochemistry, Federal University of Maranhão, São Luís, MA, Brazil. Electronic address: alexandra.ufma@gmail.com. |
| المصدر: | Experimental parasitology [Exp Parasitol] 2022 Nov; Vol. 242, pp. 108364. Date of Electronic Publication: 2022 Aug 24. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Academic Press Country of Publication: United States NLM ID: 0370713 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2449 (Electronic) Linking ISSN: 00144894 NLM ISO Abbreviation: Exp Parasitol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Orlando, FL : Academic Press Original Publication: New York. |
| مواضيع طبية MeSH: | Acaricides*/pharmacology , Rhipicephalus* , Tick Infestations*/drug therapy , Tick Infestations*/prevention & control , Tick Infestations*/veterinary, Animals ; Larva ; Monoterpenes/pharmacology |
| مستخلص: | Ticks are a widely distributed arthropod of veterinary importance. Resistance of ticks to synthetic acaricides has become widespread, warranting the development of new drugs for tick management. Carvacrol is a volatile monoterpene, with promising results against various species of ticks; however, to be used for therapeutic purposes, carvacrol must be included in a formulation that makes its application feasible. This study aims to develop a formulation of a carvacrol-containing shampoo that is effective against two species of ticks: Rhipicephalus sanguineus and R. microplus. Shampoo sensory characteristics and pH were evaluated at 37, 25 and 5 °C, for a maximum of 15 days. The shampoo remained stable at 25 and 5 °C. The efficacy of the carvacrol-containing formulation against two species of ticks was assessed by the larval immersion test. Mortality of both tick species was significantly higher for the carvacrol shampoo than for a carvacrol hydroalcoholic solution. In conclusion, the carvacrol-containing shampoo showed larvicidal efficacy on ticks. Competing Interests: Declaration of competing interest The authors declare no conflict of interest related to this work. (Copyright © 2022 Elsevier Inc. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Acaricide; Monoterpene; Shampoo |
| المشرفين على المادة: | 0 (Acaricides) 9B1J4V995Q (carvacrol) 0 (Monoterpenes) |
| تواريخ الأحداث: | Date Created: 20220826 Date Completed: 20221026 Latest Revision: 20221026 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1016/j.exppara.2022.108364 |
| PMID: | 36027929 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1090-2449 |
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| DOI: | 10.1016/j.exppara.2022.108364 |