دورية أكاديمية
A comparative analysis on risk of pulmonary hypertension in children with Atrio-ventricular (AV) canal defect: a multi-centre study.
| العنوان: | A comparative analysis on risk of pulmonary hypertension in children with Atrio-ventricular (AV) canal defect: a multi-centre study. |
|---|---|
| المؤلفون: | Chinawa JM; College of Medicine, Department of pediatrics, University of Nigeria/ University of Nigeria Teaching Hospital (UNTH), Ituku- Ozalla, Enugu State, Nigeria., Duru CO; Senior Lecturer, Department of Paediatrics and Child health.; Niger Delta University Teaching Hospital Okolobiri Bayelsa State., Chinawa AT; Enugu state University Teaching hospital, Enugu State., Chukwu BF; College of Medicine, Department of pediatrics, University of Nigeria/ University of Nigeria Teaching Hospital (UNTH), Ituku- Ozalla, Enugu State, Nigeria. |
| المصدر: | African health sciences [Afr Health Sci] 2022 Mar; Vol. 22 (1), pp. 220-226. |
| نوع المنشور: | Journal Article; Multicenter Study |
| اللغة: | English |
| بيانات الدورية: | Publisher: Faculty of Medicine, Makerere University Country of Publication: Uganda NLM ID: 101149451 Publication Model: Print Cited Medium: Internet ISSN: 1729-0503 (Electronic) Linking ISSN: 16806905 NLM ISO Abbreviation: Afr Health Sci Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Kampala, Uganda : Faculty of Medicine, Makerere University, [2001- |
| مواضيع طبية MeSH: | Heart Defects, Congenital* , Hypertension, Pulmonary*, Child ; Female ; Heart Ventricles ; Humans ; Infant ; Male |
| مستخلص: | Objectives: This study is aimed at determining the risk of pulmonary hypertension in children with AV canal defect when compared with children with other congenital heart disease. Methods: A descriptive study carried out in three institutions over a six-year period among children who presented with AV canal defect and their controls who presented with other congenital heart defects. Results: A large proportion of the children with AV canal (77.5%) had pulmonary hypertension. Among the patients with pulmonary hypertension, 45.2% were males compared 54.8% females (χ2 = 3.2, p = 0.2). There was a positive correlation between pulmonary hypertension and size of VSD and ASD, although the correlation was not significant (Pearson correlation coefficient = 0.01 and 0.4, p = 0.9 and 0.1 respectively). Children with AV canal defect had higher odds of developing most clinical symptoms and pulmonary hypertension than children with other congenital heart disease and this is statistically significant. Conclusion: Majority of children with AV canal defect presented with pulmonary hypertension. These children present with higher odds of having pulmonary hypertension and clinical symptoms than children with other types of congenital heart disease. (© 2022 Chinawa JM et al.) |
| References: | Heart. 1999 Jul;82(1):30-3. (PMID: 10377305) J Thorac Dis. 2018 Sep;10(Suppl 24):S2953-S2965. (PMID: 30305956) Genome Res. 2013 Sep;23(9):1410-21. (PMID: 23783273) Eur Heart J. 2016 Jan 1;37(1):67-119. (PMID: 26320113) Clin Cardiol. 2016 Mar;39(3):150-6. (PMID: 27001201) Am J Dis Child. 1990 Oct;144(10):1120-2. (PMID: 2144945) Circulation. 1987 Nov;76(5):1037-42. (PMID: 3664992) Eur Respir J. 2019 Jan 24;53(1):. (PMID: 30545972) Orphanet J Rare Dis. 2006 Apr 05;1:8. (PMID: 16722604) Am Fam Physician. 2011 Apr 1;83(7):829-34. (PMID: 21524049) Circ Res. 2006 Jun 9;98(11):1431-8. (PMID: 16645142) Heart. 2006 Dec;92(12):1879-85. (PMID: 17105897) J Am Coll Cardiol. 2009 Jun 30;54(1 Suppl):S43-S54. (PMID: 19555858) Cardiol Clin. 2016 Aug;34(3):391-400. (PMID: 27443136) Circulation. 2012 Jan 3;125(1):113-22. (PMID: 22086881) Arch Cardiol Mex. 2006 Jan-Mar;76(1):16-27. (PMID: 16749498) Heart. 2007 Jun;93(6):682-7. (PMID: 17164490) Pak J Med Sci. 2015 Sep-Oct;31(5):1140-5. (PMID: 26649002) |
| فهرسة مساهمة: | Keywords: AV canal defect; children; odds; pulmonary hypertension |
| تواريخ الأحداث: | Date Created: 20220829 Date Completed: 20220830 Latest Revision: 20220830 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC9382489 |
| DOI: | 10.4314/ahs.v22i1.28 |
| PMID: | 36032495 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1729-0503 |
|---|---|
| DOI: | 10.4314/ahs.v22i1.28 |