دورية أكاديمية
أعرض في EDS

Association Between Levels of Pre-operative Glycosylated Hemoglobin and Post-operative Surgical Site Infections After Elective Surgery in a Low-Income Country.

التفاصيل البيبلوغرافية
العنوان: Association Between Levels of Pre-operative Glycosylated Hemoglobin and Post-operative Surgical Site Infections After Elective Surgery in a Low-Income Country.
المؤلفون: Maqsood KM; General Surgery, Jinnah Postgraduate Medical Centre, Karachi, PAK., Pahwani R; Internal Medicine, Jinnah Sindh Medical University, Karachi, PAK., Avinash F; General Surgery, Liaquat National Hospital and Medical College, Karachi, PAK., Shabbir MR; Internal Medicine, Allama Iqbal Medical College, Lahore, PAK., Basham MA; Internal Medicine, Northwell Health, Port Jefferson, USA., Khalid A; Internal Medicine, Allama Iqbal Medical College, Lahore, PAK., Balkhi F; Internal Medicine, Jinnah Sindh Medical University, Karachi, PAK., Khalid D; Internal Medicine, Jinnah Sindh Medical University, Karachi, PAK., Jahangir M; Internal Medicine, Dow University of Health Sciences, Karachi, PAK.
المصدر: Cureus [Cureus] 2022 Jul 28; Vol. 14 (7), pp. e27397. Date of Electronic Publication: 2022 Jul 28 (Print Publication: 2022).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Cureus, Inc Country of Publication: United States NLM ID: 101596737 Publication Model: eCollection Cited Medium: Print ISSN: 2168-8184 (Print) Linking ISSN: 21688184 NLM ISO Abbreviation: Cureus Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Palo Alto, CA : Cureus, Inc.
مستخلص: Introduction: Diabetic patients undergoing surgery are more susceptible to hospital-acquired infection, particularly surgical site infection (SSI). Good glycemic control in preoperative patients significantly decreases the risk of SSI. There is a scarcity of data from low-income countries studying the relation between perioperative glycated hemoglobin (HbA1c) levels and postoperative SSI. We aim to establish statistical relation between HbA1c and SSI which will help decrease post-operative infections and morbidity.
Methods: This study was conducted in the surgical unit of Jinnah Sindh Medical University, Karachi, Pakistan, from August 2020 to April 2022. Patients who underwent elective surgical procedures (n= 1024) were included in the study and divided into two groups based on their HbA1c levels. Patients with HbA1c levels higher than 6.5% were classified as group A and those with HbA1c less than 6.5% belonged to group B. For statistical analysis, IBM SPSS Statistics for Windows, Version 24.0 (Released 2016; IBM Corp., Armonk, New York, United States) was used.
Results: Group A comprised 579 (56.5%) patients. The presence of SSI in participants with HbA1c >6.5% was statistically significant (p-value: 0.011). Genderwise comparison with the presence of SSI was found to be insignificant (p-value: 0.28). Smoking was positively correlated with the absence of SSI. No significance in terms of presence or absence of SSI was found in the comparison of the type of wounds (p-value: 0.25).
Conclusion:  There is a positive relationship between raised HbA1c levels and the development of SSI. Our study emphasizes the importance of the use of HbA1c levels as a more accurate predictor of glycemic control in pre-operative patients rather than blood glucose levels. It is imperative that surgeons must check HbA1c levels before selecting patients for elective surgeries, especially in low-income countries where the healthcare burden is already huge.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2022, Maqsood et al.)
References: World J Surg. 2022 Feb;46(2):391-399. (PMID: 34750659)
J Hosp Infect. 2017 May;96(1):1-15. (PMID: 28410761)
Diabetes Res Clin Pract. 2012 Nov;98(2):257-63. (PMID: 23084042)
JAMA. 2006 Apr 12;295(14):1681-7. (PMID: 16609090)
World J Surg. 2020 May;44(5):1450-1458. (PMID: 31974651)
Chang Gung Med J. 2012 Jan-Feb;35(1):46-53. (PMID: 22483427)
Best Pract Res Clin Endocrinol Metab. 2011 Oct;25(5):813-24. (PMID: 21925080)
Ann Med Surg (Lond). 2016 Aug 09;10:77-82. (PMID: 27570622)
Nurs Crit Care. 2009 Sep-Oct;14(5):241-53. (PMID: 19706075)
J Clin Neurosci. 2021 Nov;93:42-47. (PMID: 34656259)
Circulation. 1999 Jan 19;99(2):224-9. (PMID: 9892587)
Sci Rep. 2019 Oct 2;9(1):14240. (PMID: 31578446)
J Vasc Surg. 2021 Apr;73(4):1332-1339.e5. (PMID: 32730894)
Rev Obstet Gynecol. 2009 Fall;2(4):212-21. (PMID: 20111657)
فهرسة مساهمة: Keywords: diabetes; elective surgery; glycated hemoglobin (hba1c); random blood sugar (rbs); surgical site infection(ssi)
تواريخ الأحداث: Date Created: 20220905 Latest Revision: 20220907
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC9418640
DOI: 10.7759/cureus.27397
PMID: 36060332
قاعدة البيانات: MEDLINE
الوصف
تدمد:2168-8184
DOI:10.7759/cureus.27397