دورية أكاديمية
Studies on the synthesis of 1'-CN-triazolyl- C -ribosides.
| العنوان: | Studies on the synthesis of 1'-CN-triazolyl- C -ribosides. |
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| المؤلفون: | Bozinovic N; CY Cergy Paris Université, CNRS, BioCIS, 95000, Cergy-Pontoise, France., Aguiar VM; Biocatalysis and Organic Synthesis Group, Universidade Federal do Rio de Janeiro, Av Athos da Silveira Ramos 149, Centro de Tecnologia, Bl A, 21941909 Ilha do Fundão, Rio de Janeiro, Brazil. leandrosoter@iq.ufrj.br., Ferry A; CY Cergy Paris Université, CNRS, BioCIS, 95000, Cergy-Pontoise, France., Gallier F; CY Cergy Paris Université, CNRS, BioCIS, 95000, Cergy-Pontoise, France., Lubin-Germain N; CY Cergy Paris Université, CNRS, BioCIS, 95000, Cergy-Pontoise, France., Uziel J; CY Cergy Paris Université, CNRS, BioCIS, 95000, Cergy-Pontoise, France., Miranda LSME; CY Cergy Paris Université, CNRS, BioCIS, 95000, Cergy-Pontoise, France.; Biocatalysis and Organic Synthesis Group, Universidade Federal do Rio de Janeiro, Av Athos da Silveira Ramos 149, Centro de Tecnologia, Bl A, 21941909 Ilha do Fundão, Rio de Janeiro, Brazil. leandrosoter@iq.ufrj.br. |
| المصدر: | Organic & biomolecular chemistry [Org Biomol Chem] 2022 Sep 21; Vol. 20 (36), pp. 7261-7269. Date of Electronic Publication: 2022 Sep 21. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101154995 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-0539 (Electronic) Linking ISSN: 14770520 NLM ISO Abbreviation: Org Biomol Chem Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Cambridge, UK : Royal Society of Chemistry, c2003- |
| مواضيع طبية MeSH: | Ribonucleosides* , Ribose*, Antiviral Agents/pharmacology ; Nitriles ; Nucleosides |
| مستخلص: | The search for broad-spectrum antiviral compounds is a continuous mandatory effort. The recent approval of the first C -nucleoside carrying a nitrile as a substituent at the C1' position of the ribose ring has raised interest in this underexplored substitution pattern. We have previously reported the development of different 1,2,3-triazolyl- C -ribonucleosides with anticancer and antiviral activities. Herein we report our results on the incorporation of a C1'-CN group in 1,2,3-triazolyl- C -ribonucleosides. |
| المشرفين على المادة: | 0 (Antiviral Agents) 0 (Nitriles) 0 (Nucleosides) 0 (Ribonucleosides) 681HV46001 (Ribose) |
| تواريخ الأحداث: | Date Created: 20220907 Date Completed: 20220923 Latest Revision: 20220926 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1039/d2ob01403c |
| PMID: | 36069280 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1477-0539 |
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| DOI: | 10.1039/d2ob01403c |