دورية أكاديمية
A portable and affordable aligner for the assembly of microfluidic devices.
| العنوان: | A portable and affordable aligner for the assembly of microfluidic devices. |
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| المؤلفون: | Guglielmotti V; Instituto de Nanosistemas, Universidad Nacional de General San Martín, San Martín, Provincia de Buenos Aires, Argentina., Saffioti NA; Instituto de Nanosistemas, Universidad Nacional de General San Martín, San Martín, Provincia de Buenos Aires, Argentina., Tohmé AL; Instituto de Nanosistemas, Universidad Nacional de General San Martín, San Martín, Provincia de Buenos Aires, Argentina., Gambarotta M; Instituto de Nanosistemas, Universidad Nacional de General San Martín, San Martín, Provincia de Buenos Aires, Argentina., Corthey G; Instituto de Nanosistemas, Universidad Nacional de General San Martín, San Martín, Provincia de Buenos Aires, Argentina., Pallarola D; Instituto de Nanosistemas, Universidad Nacional de General San Martín, San Martín, Provincia de Buenos Aires, Argentina. |
| المصدر: | HardwareX [HardwareX] 2022 Aug 27; Vol. 12, pp. e00348. Date of Electronic Publication: 2022 Aug 27 (Print Publication: 2022). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101710262 Publication Model: eCollection Cited Medium: Internet ISSN: 2468-0672 (Electronic) Linking ISSN: 24680672 NLM ISO Abbreviation: HardwareX Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: [London] : Elsevier Ltd., [2017]- |
| مستخلص: | The incorporation of sophisticated capabilities within microfluidic devices often requires the assembly of different layers in a correct arrangement. For example, when it is desired to include electrodes inside microfluidic channels or to create 3D microfluidic structures. However, the alignment between different substrates at the microscale requires expensive equipment not available for all research groups. In this work, we present an affordable, compact and portable aligner for assembling multilayered composite microfluidic chips. The instrument is composed of aluminum machined pieces combined with precision stages and includes a digital microscope with a LED illumination system for monitoring the alignment process. An interchangeable holder was created for substrate fixing, allowing the bonding of PDMS with other materials. Microscopic visualization is achieved through any device with internet access, avoiding the need of a computer attached to the aligner. To test the performance of the aligner, the center of an indium tin oxide microelectrode on a glass substrate was aligned with the center of a microchannel in a PDMS chip. The accuracy and precision of the instrument are suited for many microfluidic applications. The small and inexpensive design of the aligner makes it a cost-effective option for small groups working in microfluidics. Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (© 2022 The Authors.) |
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| فهرسة مساهمة: | Keywords: Electrochemistry; Mask aligner; Microfabrication; Sensors; Soft Lithography |
| تواريخ الأحداث: | Date Created: 20220915 Latest Revision: 20220917 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC9465365 |
| DOI: | 10.1016/j.ohx.2022.e00348 |
| PMID: | 36105917 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2468-0672 |
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| DOI: | 10.1016/j.ohx.2022.e00348 |