دورية أكاديمية
Potential antidepressant effects of a dietary supplement from the chlorella and lion's mane mushroom complex in aged SAMP8 mice.
العنوان: | Potential antidepressant effects of a dietary supplement from the chlorella and lion's mane mushroom complex in aged SAMP8 mice. |
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المؤلفون: | Chou MY; International Aging Industry Research & Development Center (AIC), Providence University, Taichung, Taiwan., Ho JH; Department of Food Science, Tunghai University, Taichung, Taiwan., Huang MJ; School of General Education, Hsiuping University of Science and Technology, Taichung, Taiwan., Chen YJ; Ph.D. Program in Health and Social Welfare for Indigenous Peoples, Providence University, Taichung, Taiwan., Yang MD; Department of Surgery, Department of Clinical Nutrition, China Medical University Hospital, Taichung, Taiwan., Lin LH; Division of Allergy, Immunology & Rheumatology, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taichung, Taiwan., Chi CH; International Aging Industry Research & Development Center (AIC), Providence University, Taichung, Taiwan., Yeh CH; Taiwan Chlorella Manufacturing Co., Ltd., Taipei, Taiwan., Tsao TY; Taiwan Chlorella Manufacturing Co., Ltd., Taipei, Taiwan., Tzeng JK; Taiwan Chlorella Manufacturing Co., Ltd., Taipei, Taiwan., Hsu RJ; China Grain Products Research and Development Institute, New Taipei, Taiwan., Huang PH; College of Food, Jiangsu Food and Pharmaceutical Science College, Huai'an City, China., Lu WC; Department of Food and Beverage Management, Chung-Jen Junior College of Nursing, Health Sciences and Management, Chia-Yi City, Taiwan., Li PH; Department of Food and Nutrition, Providence University, Taichung, Taiwan., Wang MF; International Aging Industry Research & Development Center (AIC), Providence University, Taichung, Taiwan.; Department of Food and Nutrition, Providence University, Taichung, Taiwan. |
المصدر: | Frontiers in nutrition [Front Nutr] 2022 Sep 02; Vol. 9, pp. 977287. Date of Electronic Publication: 2022 Sep 02 (Print Publication: 2022). |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Frontiers Media S. A Country of Publication: Switzerland NLM ID: 101642264 Publication Model: eCollection Cited Medium: Print ISSN: 2296-861X (Print) Linking ISSN: 2296861X NLM ISO Abbreviation: Front Nutr Subsets: PubMed not MEDLINE |
أسماء مطبوعة: | Original Publication: Lausanne, Switzerland : Frontiers Media S. A., [2014]- |
مستخلص: | Since the 1990s, the prevalence of mental illnesses, such as depression, has been increasing annually and has become a major burden on society. Due to the many side effects of antidepressant drugs, the development of a complementary therapy from natural materials is an urgent need. Therefore, this study used a complex extract of chlorella and lion's mane mushroom and evaluated its antidepressant effects. Six-month-old male senescence-accelerated mice prone-8 (SAMP8) were divided into positive control; negative control; and low, medium, and high-dose groups. All groups were treated with corticosterone (CORT) at 40 mg/Kg/day for 21- days to induce depression in the animals, and the effects of different test substances on animal behavior was observed. The positive control group was intraperitoneally injected with a tricyclic antidepressant (Fluoxetine, as tricyclic antidepressant), the control group was given ddH Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2022 Chou, Ho, Huang, Chen, Yang, Lin, Chi, Yeh, Tsao, Tzeng, Hsu, Huang, Lu, Li and Wang.) |
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فهرسة مساهمة: | Keywords: antidepressant; chlorella; dietary supplement; lion's mane mushrooms; senescence accelerated mouse prone-8 (SAMP8) |
تواريخ الأحداث: | Date Created: 20220919 Latest Revision: 20220920 |
رمز التحديث: | 20221213 |
مُعرف محوري في PubMed: | PMC9479623 |
DOI: | 10.3389/fnut.2022.977287 |
PMID: | 36118772 |
قاعدة البيانات: | MEDLINE |
تدمد: | 2296-861X |
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DOI: | 10.3389/fnut.2022.977287 |