دورية أكاديمية
Postsynthetic Photocontrol of Giant Liposomes via Fusion-Based Photolipid Doping.
| العنوان: | Postsynthetic Photocontrol of Giant Liposomes via Fusion-Based Photolipid Doping. |
|---|---|
| المؤلفون: | Pritzl SD; Chair for Photonics and Optoelectronics, Nano-Institute Munich, Department of Physics, Ludwig-Maximilians-Universität (LMU), 80539 Munich, Germany., Morstein J; Department of Chemistry, New York University, Silver Center, New York 10003, United States.; Department of Cellular and Molecular Pharmacology, UCSF, San Francisco, California 94143, United States., Kahler S; Department of Chemistry, New York University, Silver Center, New York 10003, United States., Konrad DB; Department of Pharmacy, Ludwig-Maximilians-Universität (LMU), 81377 Munich, Germany., Trauner D; Department of Chemistry, New York University, Silver Center, New York 10003, United States., Lohmüller T; Chair for Photonics and Optoelectronics, Nano-Institute Munich, Department of Physics, Ludwig-Maximilians-Universität (LMU), 80539 Munich, Germany. |
| المصدر: | Langmuir : the ACS journal of surfaces and colloids [Langmuir] 2022 Oct 04; Vol. 38 (39), pp. 11941-11949. Date of Electronic Publication: 2022 Sep 21. |
| نوع المنشور: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 9882736 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5827 (Electronic) Linking ISSN: 07437463 NLM ISO Abbreviation: Langmuir Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Washington, DC : American Chemical Society, c1985- |
| مواضيع طبية MeSH: | Liposomes* , Unilamellar Liposomes*/radiation effects, Cations ; Membrane Fusion ; Phosphatidylcholines/radiation effects ; Phospholipids |
| مستخلص: | We report on photolipid doping of giant unilamellar vesicles (GUVs) via vesicle fusion with small unilamellar photolipid vesicles (pSUVs), which enables retroactive optical control of the membrane properties. We observe that vesicle fusion is light-dependent, if the phospholipids are neutral. Charge-mediated fusion involving anionic and cationic lipid molecules augments the overall fusion performance and doping efficiency, even in the absence of light exposure. Using phosphatidylcholine analogs with one or two azobenzene photoswitches ( azo - PC and d azo- PC ) affects domain formation, bending stiffness, and shape of the resulting vesicles in response to irradiation. Moreover, we show that optical membrane control can be extended to long wavelengths using red-absorbing photolipids ( red - azo - PC ). Combined, our findings present an attractive and practical method for the precise delivery of photolipids, which offers new prospects for the optical control of membrane function. |
| References: | Biophys J. 2019 Jan 8;116(1):79-91. (PMID: 30579564) J Phys Condens Matter. 2006 Jul 19;18(28):S1151-76. (PMID: 21690835) Nature. 1979 Oct 25;281(5733):690-2. (PMID: 551288) Photochem Photobiol. 1995 Jul;62(1):24-9. (PMID: 7638269) J Am Chem Soc. 2016 Oct 5;138(39):12981-12986. (PMID: 27626130) Biochimie. 2000 May;82(5):511-8. (PMID: 10865136) Nat Commun. 2020 Feb 14;11(1):905. (PMID: 32060284) Langmuir. 2017 Apr 25;33(16):4083-4089. (PMID: 28361538) Nat Nanotechnol. 2020 Apr;15(4):296-306. (PMID: 32015505) Nat Chem Biol. 2016 Sep;12(9):755-62. (PMID: 27454932) Chembiochem. 2021 Jan 5;22(1):73-83. (PMID: 32790211) Langmuir. 2018 Nov 6;34(44):13368-13374. (PMID: 30346771) Acc Chem Res. 2015 Jul 21;48(7):1947-60. (PMID: 26103428) Chem Asian J. 2017 Aug 17;12(16):2008-2028. (PMID: 28594477) Nat Chem Biol. 2019 Jun;15(6):623-631. (PMID: 31036923) Langmuir. 2022 Jan 11;38(1):385-393. (PMID: 34969246) J Am Chem Soc. 2021 Jun 16;:. (PMID: 34133158) Bioconjug Chem. 2010 Mar 17;21(3):537-43. (PMID: 20184308) Sci Rep. 2014 Nov 19;4:7107. (PMID: 25407686) Curr Opin Pharmacol. 2022 Apr;63:102202. (PMID: 35278838) Biochem Biophys Res Commun. 1999 Aug 27;262(2):406-10. (PMID: 10462488) J Biol Chem. 2009 Feb 20;284(8):4836-45. (PMID: 19124467) Langmuir. 2017 Mar 14;33(10):2671-2676. (PMID: 28190354) Langmuir. 2004 Feb 17;20(4):1152-60. (PMID: 15803690) Biochim Biophys Acta. 2010 Jul;1798(7):1338-47. (PMID: 20044978) Langmuir. 2020 Mar 17;36(10):2629-2634. (PMID: 32069411) Nat Methods. 2008 Apr;5(4):331-8. (PMID: 18311146) J Chem Phys. 2020 Jan 14;152(2):024904. (PMID: 31941331) Biochim Biophys Acta Biomembr. 2020 Nov 1;1862(11):183438. (PMID: 32781156) Cell Mol Life Sci. 2010 Feb;67(3):483-94. (PMID: 19924382) Adv Drug Deliv Rev. 1999 Aug 20;38(3):207-232. (PMID: 10837758) Biophys J. 1985 Jan;47(1):105-13. (PMID: 3978184) J Photochem Photobiol B. 2000 Sep;57(2-3):90-3. (PMID: 11154088) Langmuir. 2020 Nov 17;36(45):13509-13515. (PMID: 33143416) Annu Rev Biophys Biophys Chem. 1989;18:187-211. (PMID: 2660823) |
| معلومات مُعتمدة: | K00 CA253758 United States CA NCI NIH HHS |
| المشرفين على المادة: | 0 (Cations) 0 (Liposomes) 0 (Phosphatidylcholines) 0 (Phospholipids) 0 (Unilamellar Liposomes) |
| تواريخ الأحداث: | Date Created: 20220921 Date Completed: 20221005 Latest Revision: 20221013 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC9536078 |
| DOI: | 10.1021/acs.langmuir.2c01685 |
| PMID: | 36130117 |
| قاعدة البيانات: | MEDLINE |
Find this issue from the American Chemical Society | تدمد: | 1520-5827 |
|---|---|
| DOI: | 10.1021/acs.langmuir.2c01685 |