مراجعة
Physiopathology of the Priapism Secondary to Tamsulosin: Clinical Cases of Our Hospital and Literature Review.
| العنوان: | Physiopathology of the Priapism Secondary to Tamsulosin: Clinical Cases of Our Hospital and Literature Review. |
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| المؤلفون: | Mellado Castillero A; Unidad de Gestión Clínica de Urología, Hospital Universitario Reina Sofía, Córdoba, España., Gómez Gómez E; Unidad de Gestión Clínica de Urología, Hospital Universitario Reina Sofía, Córdoba, España., Campos Hernández JP; Unidad de Gestión Clínica de Urología, Hospital Universitario Reina Sofía, Córdoba, España., Prieto Castro R; Unidad de Gestión Clínica de Urología, Hospital Universitario Reina Sofía, Córdoba, España. |
| المصدر: | Archivos espanoles de urologia [Arch Esp Urol] 2022 Aug; Vol. 75 (6), pp. 580-583. |
| نوع المنشور: | Case Reports; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Iniestares Country of Publication: Spain NLM ID: 0064757 Publication Model: Print Cited Medium: Print ISSN: 0004-0614 (Print) Linking ISSN: 00040614 NLM ISO Abbreviation: Arch Esp Urol Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Madrid : Iniestares |
| مواضيع طبية MeSH: | Priapism*/chemically induced, Aged ; Hospitals ; Humans ; Male ; Middle Aged ; Penis/surgery ; Phenylephrine/adverse effects ; Tamsulosin/adverse effects |
| مستخلص: | Objective: To describe two cases of man with the diagnosis of ischemic priapism after the intake of tamsulosin and to revise the scientific literature. Methods: We present two cases of men that developed an ischemic priapism after the intake of tamsulosin prescribed for STUI and were treated in our hospital. We described the two cases, from the diagnosis until the surgery that was performed. Also, we review the scientific literature about this topic. Results: In one hand, a 67 years old man with the previous diagnosis of diabetes mellitus, hypertension and dyslipidemia that take a one single dosis of tamsulosin and developed a priapism of 9 hours of duration. He was diagnosticated of low-flow priapism that was reverted after the use of intracavernosal phenylephrine. On the other hand, a 61 years old man without any medical condition. He developed a priapism after the intake of also one single dosis of tamsulosin and came to the hospital after 48 hours of the beginning of the erection. In this case, the use of intracavernosal phenylephrine wasn´t effective so we decided to performed a distal shunt between cavernosal and spongy body according to the techniques of Winter, Ebbehoj and Al-Ghorab. All of them without results. At the end, we tried a proximal shunt according Quackles technique, also ineffective. The patient declined another surgery for implantation of a pennis prothesis and went home after four days of hospitalization with the disappearance of the pain. Conclusions: The tamsulosin is a drug well known by urologist that have a safety profile probed with the years. Nevertheless, it's association with a disease like the priapism forced us to explain to our patients this rare adverse effect. |
| التعليقات: | Comment in: J Urol. 2023 Apr;209(4):795-797. (PMID: 36651143) |
| فهرسة مساهمة: | Keywords: adverse effect; clinical case; physiopathology; priapism; tamsulosin |
| المشرفين على المادة: | 1WS297W6MV (Phenylephrine) G3P28OML5I (Tamsulosin) |
| تواريخ الأحداث: | Date Created: 20220922 Date Completed: 20220926 Latest Revision: 20230322 |
| رمز التحديث: | 20230322 |
| DOI: | 10.56434/j.arch.esp.urol.20227506.86 |
| PMID: | 36138510 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0004-0614 |
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| DOI: | 10.56434/j.arch.esp.urol.20227506.86 |