دورية أكاديمية
Snakebite case management: a cohort study in Northwest Ethiopia, 2012-2020.
| العنوان: | Snakebite case management: a cohort study in Northwest Ethiopia, 2012-2020. |
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| المؤلفون: | Mohammed R; Departments of Internal Medicine, University of Gondar, Gondar, Ethiopia. rezikamohammed@yahoo.com., Van Griensven J; Clinical Sciences department, Institute of Tropical Medicine, Antwerp, Belgium., Ambaw AA; University of Gondar Hospital, Gondar, Ethiopia ., Yimer TY; Departments of Internal Medicine, University of Gondar, Gondar, Ethiopia., Takarinda KC; Center for Operational Research, International Union Against Tuberculosis and Lung Disease, Paris, France., Kamau EM; UNICEF/UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases (TDR), World Health Organization, Geneva, Switzerland., Zolfo M; Clinical Sciences department, Institute of Tropical Medicine, Antwerp, Belgium., Vanlerberghe V; Public Health department, Institute of Tropical Medicine, Antwerp, Belgium. |
| المصدر: | Journal of infection in developing countries [J Infect Dev Ctries] 2022 Aug 31; Vol. 16 (8.1), pp. 52S-59S. Date of Electronic Publication: 2022 Aug 31. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Open Learning on Enteric Pathogens Country of Publication: Italy NLM ID: 101305410 Publication Model: Electronic Cited Medium: Internet ISSN: 1972-2680 (Electronic) Linking ISSN: 19722680 NLM ISO Abbreviation: J Infect Dev Ctries Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: [Italy?] : Open Learning on Enteric Pathogens |
| مواضيع طبية MeSH: | Snake Bites*/diagnosis , Snake Bites*/epidemiology , Snake Bites*/therapy, Anti-Bacterial Agents/therapeutic use ; Antivenins/therapeutic use ; Cohort Studies ; Ethiopia/epidemiology ; Female ; Humans ; Male ; Retrospective Studies |
| مستخلص: | Introduction: Timely and appropriate management of snakebites in the tropics is a lifesaver. Many snakebite patients are being bitten in remote rural areas and do not manage to get in due time to healthcare facilities. This study assessed the clinical features and the risk factors associated with treatment outcomes of snakebite patients admitted at two hospitals in the Northwest of Ethiopia. Methodology: In a retrospective cohort study, routinely collected data from 250 patients' medical charts at University of Gondar Hospital and Metema Hospital, between September 2012 and August 2020, were reviewed. Results: The median age of the snakebite cases was 24 years (95% CI = 22-26), with 80.8% male patients. At admission 148/250 patients presented in Clinical stage 1 or 2 (local symptoms only) and 73.7% presented more than 12 hours after the bite, 80.2% received antibiotics and 79.0% antivenom. The median duration of hospitalization was 3 days (95% CI = 3-4); 72% of the patients recovered and were discharged, 10.8% died and 0.5% underwent an amputation. On logistic regression analysis, residence in rural areas (AOR = 2.52, 95 % CI = 1.2-5.3), sign of bacterial superinfection on the bite site (AOR = 4.69. 95% CI = 1.4-15.4), clinical stage 3 or 4 with systemic symptoms or toxic signs at admission (AOR = 4.84, 95% CI = 1.3-18.0) and no treatment with antivenoms (AOR = 6.65, 95% CI = 1.6-27.7) were associated with bad outcome (death, amputation and/or referred/ went against medical advice). Conclusions: Timely presentation at early clinical stage, appropriate clinical management and availability of antivenoms are cornerstones to reduce snakebite morbidity and mortality. Competing Interests: No Conflict of Interest is declared (Copyright (c) 2022 Rezika Mohammed, Johan van Griensven, Addisu Alemu Ambaw, Tesfaye Yesuf Yimer, Kudakwashe Collin Takarinda, Edward Mberu Kamau, Maria Zolfo, Veerle Vanlerberghe.) |
| معلومات مُعتمدة: | 001 International WHO_ World Health Organization |
| فهرسة مساهمة: | Keywords: Neglected tropical diseases; SORT IT; management of snakebite; operational research; sub-Saharan Africa |
| المشرفين على المادة: | 0 (Anti-Bacterial Agents) 0 (Antivenins) |
| تواريخ الأحداث: | Date Created: 20220926 Date Completed: 20220928 Latest Revision: 20221108 |
| رمز التحديث: | 20221213 |
| DOI: | 10.3855/jidc.15971 |
| PMID: | 36156503 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1972-2680 |
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| DOI: | 10.3855/jidc.15971 |