دورية أكاديمية
أعرض في EDS

Does pregabalin act in pain control after lateral pharyngoplasties and tonsillectomies? A pilot study.

التفاصيل البيبلوغرافية
العنوان: Does pregabalin act in pain control after lateral pharyngoplasties and tonsillectomies? A pilot study.
المؤلفون: Rocha LF; Resident Physician at the Department of Otolaryngology, Head and Neck Surgery, Hospital Federal da Lagoa, Rio de Janeiro, Brazil. drlucasfrocha@gmail.com., de Figueiredo Mello L; Resident Physician at the Department of Otolaryngology, Head and Neck Surgery, Hospital Federal da Lagoa, Rio de Janeiro, Brazil., Silva DTE; Resident Physician at the Department of Otolaryngology, Head and Neck Surgery, Hospital Federal da Lagoa, Rio de Janeiro, Brazil., Ferreira NSS; Resident Physician at the Department of Otolaryngology, Head and Neck Surgery, Hospital Federal da Lagoa, Rio de Janeiro, Brazil., Salgado APF; Resident Physician at the Department of Otolaryngology, Head and Neck Surgery, Hospital Federal da Lagoa, Rio de Janeiro, Brazil., Júnior SCG; Oswaldo Cruz Foundation, Fernandes Figueira Institute, Rio de Janeiro, Brazil.
المصدر: Sleep & breathing = Schlaf & Atmung [Sleep Breath] 2023 Jun; Vol. 27 (3), pp. 1107-1110. Date of Electronic Publication: 2022 Sep 29.
نوع المنشور: Randomized Controlled Trial; Journal Article
اللغة: English
بيانات الدورية: Publisher: Springer Country of Publication: Germany NLM ID: 9804161 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1709 (Electronic) Linking ISSN: 15209512 NLM ISO Abbreviation: Sleep Breath Subsets: MEDLINE
أسماء مطبوعة: Publication: 2005- : Heidelberg ; New York : Springer
Original Publication: Titisee-Neustadt, Germany : Druckbild GmbH,
مواضيع طبية MeSH: Analgesics*/therapeutic use , Tonsillectomy*/adverse effects, Humans ; Pregabalin/therapeutic use ; Pilot Projects ; Analgesics, Opioid/therapeutic use ; Dizziness/chemically induced ; Dizziness/drug therapy ; Pain, Postoperative/drug therapy ; Pain, Postoperative/etiology
مستخلص: Objective: Some studies have pointed to gabapentinoids as promising medications in postoperative pain control. The objective of the present study was to evaluate the efficacy of pregabalin in reducing postoperative pain in tonsillectomy and lateral pharyngoplasties.
Study Design: Double-blind randomized controlled trial.
Setting: Tertiary care center.
Methods: A double-blind randomized controlled trial was conducted with patients undergoing tonsillectomies and lateral pharyngoplasties between Aug 29, 2017, and Oct 31, 2020. Data of interest such as opioid consumption, pain scores, and adverse outcomes such as dizziness, nausea, headache, and sedation within 7 days following surgeries were analyzed.
Results: No statistically significant difference was observed in pain scores and opioid consumption between the groups studied in the pilot project. The use of pregabalin was associated with lower incidence of dizziness compared to controls.
Conclusion: Gabapentinoids, especially pregabalin, are drugs whose potential for controlling pain after pharyngeal surgery, such as tonsillectomy and sleep apnea surgery, still needs to be more fully evaluated. After the conclusion of the present study, we hope to answer this question about the role of pregabalin in oropharyngeal surgeries.
(© 2022. The Author(s), under exclusive licence to Springer Nature Switzerland AG.)
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فهرسة مساهمة: Keywords: Pain; Postoperative; Pregabalin; Tonsillectomy
المشرفين على المادة: 55JG375S6M (Pregabalin)
0 (Analgesics)
0 (Analgesics, Opioid)
تواريخ الأحداث: Date Created: 20220928 Date Completed: 20230531 Latest Revision: 20230531
رمز التحديث: 20230531
DOI: 10.1007/s11325-022-02715-x
PMID: 36171512
قاعدة البيانات: MEDLINE
الوصف
تدمد:1522-1709
DOI:10.1007/s11325-022-02715-x