دورية أكاديمية

Characteristics and outcomes of COVID-19 among people living with HIV at Eka Kotebe General Hospital, Addis Ababa, Ethiopia.

التفاصيل البيبلوغرافية
العنوان: Characteristics and outcomes of COVID-19 among people living with HIV at Eka Kotebe General Hospital, Addis Ababa, Ethiopia.
المؤلفون: Ahmed NS; Eka Kotebe General Hospital, Addis Ababa, Ethiopia., Nega SS; Eka Kotebe General Hospital, Addis Ababa, Ethiopia., Deyessa N; College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia., Gebremariam TH; College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia., Ahmed HY; College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia., Etissa EK; College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia., Huluka DK; College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
المصدر: IJID regions [IJID Reg] 2022 Dec; Vol. 5, pp. 124-129. Date of Electronic Publication: 2022 Sep 24.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 9918418183106676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2772-7076 (Electronic) Linking ISSN: 27727076 NLM ISO Abbreviation: IJID Reg Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: [Amsterdam] : Elsevier Ltd., [2021]-
مستخلص: Introduction: Evidence on the interplay between HIV and COVID-19 is not entirely consistent.
Methods: A retrospective cohort study was conducted on the medical records of patients who had a positive RT-PCR for COVID-19 and were admitted to Eka Kotebe General Hospital between March 2020 and October 2021.
Results: A total of 427 patients, including 108 people living with HIV/AIDS (PLWH) and 319 people without HIV/AIDS, were included in the study. The median age of PLWH and people without HIV was 49.5 years (interquartile range 40-59 years) and 48 years (interquartile range 32-65 years), respectively. Of these patients, 258 (60.4%) were male and 169 (39.6%) were female. There were significant differences between PLWH and people without HIV in terms of age, tuberculosis, pregnancy, chronic liver disease, complications, shock, white blood cell count, and end outcome (alive or dead). There was no association between HIV status and the need for oxygen, intensive care unit admission, or disease severity. After adjusting for other variables, mortality was significantly higher among PLWH (adjusted odds ratio 2.25, 95% confidence interval 1.11-5.56; P  = 0.023).
Conclusions: PLWH with COVID-19 had a higher rate of in-hospital mortality than people without HIV, although no association was found between HIV status and the requirement for intensive care unit admission, mechanical ventilation, oxygen support, or the severity of the disease at the time of admission.
(© 2022 The Authors.)
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معلومات مُعتمدة: D43 TW009127 United States TW FIC NIH HHS
فهرسة مساهمة: Keywords: COVID-19; Ethiopia; HIV
تواريخ الأحداث: Date Created: 20221003 Latest Revision: 20240604
رمز التحديث: 20240604
مُعرف محوري في PubMed: PMC9507779
DOI: 10.1016/j.ijregi.2022.09.009
PMID: 36185781
قاعدة البيانات: MEDLINE
الوصف
تدمد:2772-7076
DOI:10.1016/j.ijregi.2022.09.009