دورية أكاديمية
أعرض في EDS

Effectiveness of an integrative medicine approach to improve cognitive dysfunction and dementia: An observational study.

التفاصيل البيبلوغرافية
العنوان: Effectiveness of an integrative medicine approach to improve cognitive dysfunction and dementia: An observational study.
المؤلفون: Lee JH; Woorisaam Oriental Medicine Clinic, Goyang, South Korea., Kim MG; Department of Oriental Neuropsychiatry, Dongguk University Ilsan Korean Medicine Hospital, Goyang, South Korea.; Department of Oriental Neuropsychiatry, Graduate School of Dongguk University, Seoul, South Korea., Kim DY; Department of Internal Medicine, Dongguk University Ilsan Hospital, Goyang, South Korea., Shin HW; UCI Memory Impairments and Neurological Disorders (UCI MIND), Irvine, CA, USA.; RIIID Medical Group of Irvine, Irvine, CA, USA., Kang H; Biostatistics and Center for Quantitative Sciences, Vanderbilt University, Nashville, TN, USA., Koo BS; Department of Oriental Neuropsychiatry, Dongguk University Ilsan Korean Medicine Hospital, Goyang, South Korea.; Department of Oriental Neuropsychiatry, Graduate School of Dongguk University, Seoul, South Korea., Kim KK; Department of Neurology, Dongguk University Ilsan Hospital, Goyang, South Korea.
المصدر: Medicine [Medicine (Baltimore)] 2022 Sep 23; Vol. 101 (38), pp. e30301.
نوع المنشور: Journal Article; Observational Study
اللغة: English
بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 2985248R Publication Model: Print Cited Medium: Internet ISSN: 1536-5964 (Electronic) Linking ISSN: 00257974 NLM ISO Abbreviation: Medicine (Baltimore) Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Hagerstown, Md : Lippincott Williams & Wilkins
مواضيع طبية MeSH: Cognitive Dysfunction*/diagnosis , Cognitive Dysfunction*/therapy , Dementia*/complications , Dementia*/diagnosis , Dementia*/therapy , Integrative Medicine*, Anticonvulsants ; Cognition ; Donepezil/therapeutic use ; Humans ; Neuropsychological Tests ; Retrospective Studies
مستخلص: Despite the urgent need to control dementia, an effective treatment has yet to be developed. Along with the Korean government's policy of cooperation between conventional medicine (CM) and Korean medicine (KM), integrative medical services for dementia patients are being provided. This study aimed to compare the integrative medical clinic (IMC) for dementia used by Dongguk University Hospitals (DUH) with other service models and to review the characteristics and treatment outcomes of patients who had visited DUH over the past 5 years. Patients' electronic medical records from May 2015 to June 2020 were searched and their data were analyzed to evaluate the IMC's service model. Patient demographic and clinical characteristics, diagnostic tests, and treatment patterns for CM and KM were collected. The proportion of patients who did not show worsening cognitive function was described in detail. A strength of the DUH integrative medicine clinic is its ability to manage both KM and CM patients in the same space at the same time. Among the 82 patients who visited the clinic during our study period, 56 remained for data analysis after we excluded patients who met the exclusion criteria; nineteen patients had diagnoses of mild cognitive impairment. Among collaboration patterns, the first visit to the IMC had the highest proportion (55.4%). Among diagnosed tests in CM, laboratory tests and neuropsychological tests were used the most. In KM, a heart rate variability test was frequently used. The most common CM treatment prescribed was anticonvulsants, with 22 patients (39.2%) receiving donepezil, whereas the most frequent KM treatments were acupuncture (82.1%) and herbal medicine (78.6%). Twelve patients were followed up with the Mini-Mental State Examination, and 8 demonstrated either no worsening or improved cognition (baseline Mini-Mental State Examination range: 21-26). All 8 patients had mild cognitive impairment including 6 with amnestic, multidomain impairment. This study searched for a way to improve cognitive dysfunction and dementia using an integrative approach, and it shows promising results for mild cognitive impairment. However, more precisely designed follow-up studies are needed to address the present work's limitations of a retrospective study design and a small sample size.
Competing Interests: The authors have no conflicts of interest to disclose.
(Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.)
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المشرفين على المادة: 0 (Anticonvulsants)
8SSC91326P (Donepezil)
تواريخ الأحداث: Date Created: 20221005 Date Completed: 20221007 Latest Revision: 20230215
رمز التحديث: 20230215
مُعرف محوري في PubMed: PMC9509052
DOI: 10.1097/MD.0000000000030301
PMID: 36197176
قاعدة البيانات: MEDLINE
الوصف
تدمد:1536-5964
DOI:10.1097/MD.0000000000030301