دورية أكاديمية
أعرض في EDS

Post-Irradiation Recovery of B14-150 Fibrosarcoma Cells after Combined Irradiation with Low and High Linear Energy Transfer.

التفاصيل البيبلوغرافية
العنوان: Post-Irradiation Recovery of B14-150 Fibrosarcoma Cells after Combined Irradiation with Low and High Linear Energy Transfer.
المؤلفون: Koryakina EV; A. F. Tsyb Medical Radiological Research Center - Affiliated Branch of the National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Obninsk, Russia. ek-koryakina@mrrc.obninsk.ru., Potetnya VI; A. F. Tsyb Medical Radiological Research Center - Affiliated Branch of the National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Obninsk, Russia., Troshina MV; A. F. Tsyb Medical Radiological Research Center - Affiliated Branch of the National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Obninsk, Russia., Solov'ev AN; A. F. Tsyb Medical Radiological Research Center - Affiliated Branch of the National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Obninsk, Russia., Saburov VO; A. F. Tsyb Medical Radiological Research Center - Affiliated Branch of the National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Obninsk, Russia., Lychagin AA; A. F. Tsyb Medical Radiological Research Center - Affiliated Branch of the National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Obninsk, Russia., Koryakin SN; A. F. Tsyb Medical Radiological Research Center - Affiliated Branch of the National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Obninsk, Russia.; Obninsk Institute for Nuclear Power Engineering, National Research Nuclear University (MEPhI), Obninsk, Russia., Ivanov SA; A. F. Tsyb Medical Radiological Research Center - Affiliated Branch of the National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Obninsk, Russia.; Peoples' Friendship University of Russia (RUDN University), Moscow, Russia., Kaprin AD; National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Obninsk, Russia.; Peoples' Friendship University of Russia (RUDN University), Moscow, Russia.
المصدر: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2022 Sep; Vol. 173 (5), pp. 641-644. Date of Electronic Publication: 2022 Oct 10.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Springer Country of Publication: United States NLM ID: 0372557 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-8221 (Electronic) Linking ISSN: 00074888 NLM ISO Abbreviation: Bull Exp Biol Med Subsets: MEDLINE
أسماء مطبوعة: Publication: New York : Springer
Original Publication: New York, Consultants Bureau.
مواضيع طبية MeSH: Fibrosarcoma*/radiotherapy , Linear Energy Transfer*, Dose-Response Relationship, Radiation ; Humans ; Protons
مستخلص: The use of radiation with low and high linear energy transfer (LET) in the same treatment regimen is promising in terms of increasing the efficiency and reducing the severity of radiation complications. Here we studied combined effect of protons (LET≈3 keV/μm) and heavy recoils (HR) induced by 14.5 MeV neutrons (LET≈290 keV/μm) on B14-150 fibrosarcoma cells. Comparison of the 4 irradiation schemes with different high-LET/low-LET dose ratios and the irradiation sequences revealed higher effectiveness of the combined action in the HR→protons sequence and with increasing HR dose contribution to 40% of the total dose. The observed effects were due to differences in the recovery of damages induced in cells by radiations with low and high LET.
(© 2022. Springer Science+Business Media, LLC, part of Springer Nature.)
References: Bennan ABA, Unkelbach J, Wahl N, Salome P, Bangert M. Joint optimization of photon-carbon ion treatments for glioblastoma. Int. J. Radiat. Oncol. Biol. Phys. 2021;111(2):559-572. https://doi.org/10.1016/j.ijrobp.2021.05.126. (PMID: 10.1016/j.ijrobp.2021.05.12634058258)
Schulz-Ertner D, Nikoghosyan A, Jäkel O, Haberer T, Kraft G, Scholz M, Wannenmacher M, Debus J. Feasibility and toxicity of combined photon and carbon ion radiotherapy for locally advanced adenoid cystic carcinomas. Int. J. Radiat. Oncol. Biol. Phys. 2003;56(2):391-398. https://doi.org/10.1016/s0360-3016(02)04511-x. (PMID: 10.1016/s0360-3016(02)04511-x12738314)
Dokic I, Mairani A, Niklas M, Zimmermann F, Chaudhri N, Krunic D, Tessonnier T, Ferrari A, Parodi K, Jäkel O, Debus J, Haberer T, Abdollahi A. Next generation multi-scale biophysical characterization of high precision cancer particle radiotherapy using clinical proton, helium-, carbon- and oxygen ion beams. Oncotarget. 2016;7(35):56 676-56 689. https://doi.org/10.18632/oncotarget.10996.
Kopp B, Mein S, Dokic I, Harrabi S, Böhlen TT, Haberer T, Debus J, Abdollahi A, Mairani A. Development and validation of single field multi-ion particle therapy treatments. Int. J. Radiat. Oncol. Biol. Phys. 2020;106(1):194-205. https://doi.org/10.1016/j.ijrobp.2019.10.008. (PMID: 10.1016/j.ijrobp.2019.10.00831610250)
Sokol O, Krämer M, Hild S, Durante M, Scifoni E. Kill painting of hypoxic tumors with multiple ion beams. Phys. Med. Biol. 2019;64(4):045008. https://doi.org/10.1088/1361-6560/aafe40. (PMID: 10.1088/1361-6560/aafe4030641490)
Obaturov GM, Potetnya VI. Combined effect of radiation of different quality. Atomn. Energiya. 1998;84(1):42-50. Russian.
Koryakina EV, Potetnya VI, Troshina MV, Efimova MN, Baykuzina RM, Koryakin SN, Lychagin AA, Pikalov VA, Ulyanenko SE. Comparison of biological efficiency of accelerated carbon ions and heavy recoils in chinese hamster cells. Radiat. Risk 2019;28(3):96-106. Russian. https://doi.org/10.21870/0131-3878-2019-28-3-96-106.
Freshney RJ. Culture of Animal Cells. Moscow, 2010. Russian.
فهرسة مساهمة: Keywords: B14-150 fibrosarcoma cells; cell survival; heavy recoils (HR); low- and high-LET irradiations; protons
المشرفين على المادة: 0 (Protons)
تواريخ الأحداث: Date Created: 20221009 Date Completed: 20221014 Latest Revision: 20221014
رمز التحديث: 20240628
DOI: 10.1007/s10517-022-05604-1
PMID: 36210417
قاعدة البيانات: MEDLINE
الوصف
تدمد:1573-8221
DOI:10.1007/s10517-022-05604-1