دورية أكاديمية

Estimating the Effects of a Complex, Multidimensional Moderator: An Example of Latent Class Moderation to Examine Differential Intervention Effects of Substance Use Services.

التفاصيل البيبلوغرافية
العنوان: Estimating the Effects of a Complex, Multidimensional Moderator: An Example of Latent Class Moderation to Examine Differential Intervention Effects of Substance Use Services.
المؤلفون: Bray BC; Institute for Health Research and Policy, University of Illinois Chicago, 1747 W Roosevelt Rd., IL, 60608, Chicago, USA. bcbray@uic.edu., Layland EK; Department of Human Development and Family Sciences, University of Delaware, 111 Alison Hall West, Newark, DE, 19716, USA., Stull SW; Edna Bennett Pierce Prevention Research Center, The Pennsylvania State Univerity, 314 Biobehavioral Health Bldg., PA, 16802, University Park, USA.; Department of Biobehavioral Health, The Pennsylvania State University, 314 Biobehavioral Health Bldg, University Park, PA, 16802, USA., Vasilenko SA; Department of Human Development and Family Science, Syracuse University, 144 White Hall, Syracuse, NY, 13244, USA., Lanza ST; Edna Bennett Pierce Prevention Research Center, The Pennsylvania State Univerity, 314 Biobehavioral Health Bldg., PA, 16802, University Park, USA.; Department of Biobehavioral Health, The Pennsylvania State University, 314 Biobehavioral Health Bldg, University Park, PA, 16802, USA.
المصدر: Prevention science : the official journal of the Society for Prevention Research [Prev Sci] 2023 Apr; Vol. 24 (3), pp. 493-504. Date of Electronic Publication: 2022 Oct 12.
نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
اللغة: English
بيانات الدورية: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 100894724 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-6695 (Electronic) Linking ISSN: 13894986 NLM ISO Abbreviation: Prev Sci Subsets: MEDLINE
أسماء مطبوعة: Original Publication: New York, NY : Kluwer Academic/Plenum Publishers, c2000-
مواضيع طبية MeSH: Substance-Related Disorders*, Adolescent ; Humans
مستخلص: Improvements in substance use disorder recovery may be achieved by recognizing that effective interventions do not work equally well for all individuals. Heterogeneity of intervention effects is traditionally examined as a function of a single variable, such as gender or baseline severity. However, responsiveness to an intervention is likely a result of multiple, intersecting factors. Latent class moderation enables the examination of heterogeneity in intervention effects across subgroups characterized by profiles of characteristics. This study analyzed data from adolescents (aged 13 to 18 years old) who needed treatment for cannabis use (n = 14,854) and participated in the Global Appraisal of Individual Needs to evaluate differential effects of substance use services on cannabis use outcomes. We demonstrate an adjusted three-step approach using weights that account for measurement error; sample codes in Mplus and Latent Gold are provided and data are publicly available. Indicators of the latent class moderator comprised six contextual (e.g., recovery environment risk) and individual (e.g., internal mental distress) risk factors. The latent class moderator comprised four subgroups: low risk (21.1%), social risk (21.1%), environmental risk (12.5%), and mixed risk (45.2%). Limited moderation of associations between level of care and any past 90-day cannabis use were observed. In predicting number of cannabis use-days, compared to individuals with low risk, those with environmental risk showed improved outcomes from intensive outpatient care whereas individuals with social risk and mixed risk showed improved outcomes from residential care (all compared to early intervention/outpatient care). Latent class moderation holds potential to elucidate heterogeneity in intervention effectiveness that otherwise may go undetected.
(© 2022. Society for Prevention Research.)
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معلومات مُعتمدة: P50 DA039838 United States DA NIDA NIH HHS; R01 DA037902 United States DA NIDA NIH HHS; T32 MH020031 United States MH NIMH NIH HHS; R01-DA037902 United States DA NIDA NIH HHS
فهرسة مساهمة: Keywords: Cannabis use; Differential effects; Latent class analysis; Moderation; Substance use services
تواريخ الأحداث: Date Created: 20221012 Date Completed: 20230421 Latest Revision: 20240406
رمز التحديث: 20240406
مُعرف محوري في PubMed: PMC10090219
DOI: 10.1007/s11121-022-01448-3
PMID: 36223045
قاعدة البيانات: MEDLINE
الوصف
تدمد:1573-6695
DOI:10.1007/s11121-022-01448-3