دورية أكاديمية

The Involvement of Smooth Muscle, Striated Muscle, and the Myocardium in Scleroderma: A Review.

التفاصيل البيبلوغرافية
العنوان: The Involvement of Smooth Muscle, Striated Muscle, and the Myocardium in Scleroderma: A Review.
المؤلفون: Bratoiu I; Department of Rheumatology and Physiotherapy, 'Grigore T. Popa' University of Medicine and Pharmacy, 16 University Street, 700115 Iasi, Romania., Burlui AM; Department of Rheumatology and Physiotherapy, 'Grigore T. Popa' University of Medicine and Pharmacy, 16 University Street, 700115 Iasi, Romania., Cardoneanu A; Department of Rheumatology and Physiotherapy, 'Grigore T. Popa' University of Medicine and Pharmacy, 16 University Street, 700115 Iasi, Romania., Macovei LA; Department of Rheumatology and Physiotherapy, 'Grigore T. Popa' University of Medicine and Pharmacy, 16 University Street, 700115 Iasi, Romania., Richter P; Department of Rheumatology and Physiotherapy, 'Grigore T. Popa' University of Medicine and Pharmacy, 16 University Street, 700115 Iasi, Romania., Rusu-Zota G; Department of Pharmacology, 'Grigore T. Popa' University of Medicine and Pharmacy, 16 University Street, 700115 Iasi, Romania., Rezus C; Department of Internal Medicine, Faculty of Medicine, 'Grigore T. Popa' University of Medicine and Pharmacy, 16 Universitatii Street, 700115 Iasi, Romania., Badescu MC; Department of Internal Medicine, Faculty of Medicine, 'Grigore T. Popa' University of Medicine and Pharmacy, 16 Universitatii Street, 700115 Iasi, Romania., Szalontay A; Department of Psychiatry, 'Grigore T. Popa' University of Medicine and Pharmacy, 16 University Street, 700115 Iasi, Romania., Rezus E; Department of Rheumatology and Physiotherapy, 'Grigore T. Popa' University of Medicine and Pharmacy, 16 University Street, 700115 Iasi, Romania.
المصدر: International journal of molecular sciences [Int J Mol Sci] 2022 Oct 09; Vol. 23 (19). Date of Electronic Publication: 2022 Oct 09.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI, [2000-
مواضيع طبية MeSH: Muscular Diseases*/pathology , Scleroderma, Systemic*/pathology, Humans ; Muscle, Skeletal/pathology ; Muscle, Smooth/pathology ; Myocardium/pathology
مستخلص: Systemic sclerosis (SSc) is a complex autoimmune disease characterized by heterogeneous changes involving numerous organs and systems. The currently available data indicate that muscle injury (both smooth and striated muscles) is widespread and leads to significant morbidity, either directly or indirectly. From the consequences of smooth muscle involvement in the tunica media of blood vessels or at the level of the digestive tract, to skeletal myopathy (which may be interpreted strictly in the context of SSc, or as an overlap with idiopathic inflammatory myopathies), muscular injury in scleroderma translates to a number of notable clinical manifestations. Heart involvement in SSc is heterogenous depending on the definition used in the various studies. The majority of SSc patients experience a silent form of cardiac disease. The present review summarizes certain important features of myocardial, as well as smooth and skeletal muscle involvement in SSc. Further research is needed to fully describe and understand the pathogenic pathways and the implications of muscle involvement in scleroderma.
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فهرسة مساهمة: Keywords: myositis; sarcopenia; skeletal muscle; smooth muscle; systemic sclerosis
تواريخ الأحداث: Date Created: 20221014 Date Completed: 20221017 Latest Revision: 20221019
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC9569846
DOI: 10.3390/ijms231912011
PMID: 36233313
قاعدة البيانات: MEDLINE
الوصف
تدمد:1422-0067
DOI:10.3390/ijms231912011