Associations between breast milk intake volume, macronutrient intake and infant growth in a longitudinal birth cohort: the Cambridge Baby Growth and Breastfeeding Study (CBGS-BF).

التفاصيل البيبلوغرافية
العنوان:	Associations between breast milk intake volume, macronutrient intake and infant growth in a longitudinal birth cohort: the Cambridge Baby Growth and Breastfeeding Study (CBGS-BF).
المؤلفون:	Olga L; Department of Paediatrics, University of Cambridge, Cambridge, UK., Vervoort J; Department of Agrotechnology and Food Sciences, Wageningen University, Wageningen, the Netherlands., van Diepen JA; Medical and Scientific Affairs, Reckitt/Mead Johnson Nutrition Institute, Nijmegen, the Netherlands; Evansville, IN, USA., Gross G; Medical and Scientific Affairs, Reckitt/Mead Johnson Nutrition Institute, Nijmegen, the Netherlands; Evansville, IN, USA., Petry CJ; Department of Paediatrics, University of Cambridge, Cambridge, UK., Prentice PM; Department of Paediatrics, University of Cambridge, Cambridge, UK., Chichlowski M; Medical and Scientific Affairs, Reckitt/Mead Johnson Nutrition Institute, Nijmegen, the Netherlands; Evansville, IN, USA., van Tol EAF; Medical and Scientific Affairs, Reckitt/Mead Johnson Nutrition Institute, Nijmegen, the Netherlands; Evansville, IN, USA., Hughes IA; Department of Paediatrics, University of Cambridge, Cambridge, UK., Dunger DB; Department of Paediatrics, University of Cambridge, Cambridge, UK.; Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Ong KK; Department of Paediatrics, University of Cambridge, Cambridge, UK.; Institute of Metabolic Science, University of Cambridge, Cambridge, UK.; MRC Epidemiology Unit, Wellcome Trust-MRC Institute of Metabolic Science, NIHR Cambridge Comprehensive Biomedical Research Centre, Cambridge Biomedical Campus, University of Cambridge, Cambridge, CB2 0QQ, UK.
المصدر:	The British journal of nutrition [Br J Nutr] 2023 Jul 14; Vol. 130 (1), pp. 56-64. Date of Electronic Publication: 2022 Oct 19.
نوع المنشور:	Journal Article; Research Support, Non-U.S. Gov't
اللغة:	English
بيانات الدورية:	Publisher: Published on behalf of the Nutrition Society by CABI Publishing Country of Publication: England NLM ID: 0372547 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1475-2662 (Electronic) Linking ISSN: 00071145 NLM ISO Abbreviation: Br J Nutr Subsets: MEDLINE
أسماء مطبوعة:	Publication: <2000->: Wallingford, Oxon, UK : Published on behalf of the Nutrition Society by CABI Publishing Original Publication: [Cambridge, New York] Cambridge University Press.
مواضيع طبية MeSH:	Breast Feeding* , Milk, Human*/chemistry, Infant, Newborn ; Humans ; Infant ; Female ; Pregnancy ; Infant Nutritional Physiological Phenomena ; Obesity ; Eating ; Carbohydrates/analysis
مستخلص:	Growth patterns of breastfed infants show substantial inter-individual differences, partly influenced by breast milk (BM) nutritional composition. However, BM nutritional composition does not accurately indicate BM nutrient intakes. This study aimed to examine the associations between both BM intake volumes and macronutrient intakes with infant growth. Mother-infant dyads ( n 94) were recruited into the Cambridge Baby Growth and Breastfeeding Study (CBGS-BF) from a single maternity hospital at birth; all infants received exclusive breast-feeding (EBF) for at least 6 weeks. Infant weight, length and skinfolds thicknesses (adiposity) were repeatedly measured from birth to 12 months. Post-feed BM samples were collected at 6 weeks to measure TAG (fat), lactose (carbohydrate) (both by ¹ H-NMR) and protein concentrations (Dumas method). BM intake volume was estimated from seventy infants between 4 and 6 weeks using dose-to-the-mother deuterium oxide ( ² H 2 O) turnover. In the full cohort and among sixty infants who received EBF for 3+ months, higher BM intake at 6 weeks was associated with initial faster growth between 0 and 6 weeks ( β + se 3·58 + 0·47 for weight and 4·53 + 0·6 for adiposity gains, both P < 0·0001) but subsequent slower growth between 3 and 12 months ( β + se - 2·27 + 0·7 for weight and -2·65 + 0·69 for adiposity gains, both P < 0·005). BM carbohydrate and protein intakes at 4-6 weeks were positively associated with early (0-6 weeks) but tended to be negatively related with later (3-12 months) adiposity gains, while BM fat intake showed no association, suggesting that carbohydrate and protein intakes may have more functional relevance to later infant growth and adiposity.
References:	Diabetologia. 2019 Nov;62(11):1977-1987. (PMID: 31396660) Acta Paediatr. 2016 Jun;105(6):641-7. (PMID: 26865238) Nutrients. 2018 Dec 03;10(12):. (PMID: 30513944) Eur J Nutr. 2013 Feb;52(1):1-24. (PMID: 22810464) J Pediatr Gastroenterol Nutr. 2014 Jul;59(1):70-7. (PMID: 24637965) Nutrients. 2018 Nov 26;10(12):. (PMID: 30486227) Int J Obes (Lond). 2013 Aug;37(8):1116-22. (PMID: 23147117) Am J Clin Nutr. 2008 May;87(5):1558S-1561S. (PMID: 18469287) Rev Endocr Metab Disord. 2020 Sep;21(3):341-353. (PMID: 32827096) Am J Clin Nutr. 2012 Mar;95(3):656-69. (PMID: 22301930) Pediatr Clin North Am. 2013 Feb;60(1):49-74. (PMID: 23178060) Br J Nutr. 2015 Jul;114(2):316-27. (PMID: 26131962) Br J Nutr. 2012 Aug;108 Suppl 2:S105-12. (PMID: 23107521) Nutr Rev. 2021 Nov 10;79(12):1353-1361. (PMID: 33448303) Nestle Nutr Workshop Ser Pediatr Program. 2006;58:51-9; discussion 59-63. (PMID: 16902325) PLoS One. 2015 Jul 20;10(7):e0133326. (PMID: 26192417) Pediatr Res. 2002 Dec;52(6):863-7. (PMID: 12438662) Am J Clin Nutr. 2004 Mar;79(3):494-501. (PMID: 14985227) Pediatrics. 2006 Mar;117(3):e387-95. (PMID: 16510619) Am J Clin Nutr. 2015 Feb;101(2):319-25. (PMID: 25646329) Pediatrics. 2000 Dec;106(6):1355-66. (PMID: 11099589) Nutrients. 2021 Aug 21;13(8):. (PMID: 34445039) Am J Clin Nutr. 2009 Apr;89(4):1019-24. (PMID: 19225118) Am J Clin Nutr. 1991 Feb;53(2):457-65. (PMID: 1989413) Nestle Nutr Inst Workshop Ser. 2016;85:101-9. (PMID: 27088337) J Pediatr Gastroenterol Nutr. 2010 Dec;51 Suppl 3:S151-2. (PMID: 21088544) Int J Environ Res Public Health. 2016 Aug 23;13(9):. (PMID: 27563917) J Hum Lact. 2013 Feb;29(1):81-9. (PMID: 22797414) J Nutr. 2020 Nov 19;150(11):2924-2930. (PMID: 32886106) Arch Dis Child. 2022 Nov;107(11):1034-1037. (PMID: 35840313) Nutr Rev. 2002 Aug;60(8):235-51. (PMID: 12199299) J Nutr. 2016 Jan;146(1):21-9. (PMID: 26674762) Pediatrics. 1992 Jun;89(6 Pt 1):1035-41. (PMID: 1594343) Eur J Clin Nutr. 2003 Dec;57(12):1633-42. (PMID: 14647230) Int J Obes (Lond). 2014 Jul;38(7):980-7. (PMID: 24722545) Int J Obes Relat Metab Disord. 2003 Feb;27(2):162-72. (PMID: 12586995) Adv Nutr. 2015 May 15;6(3):260-6. (PMID: 25979491) J Nutr. 2010 Dec;140(12):2227-32. (PMID: 20980653) Physiol Behav. 2008 Apr 22;94(1):8-16. (PMID: 18191968) Proc Nutr Soc. 2009 Nov;68(4):422-9. (PMID: 19698202) Ann Hum Biol. 2021 Sep;48(6):455-465. (PMID: 35105200)
معلومات مُعتمدة:	MC_UU_00006/2 United Kingdom MRC_ Medical Research Council; MC_UU_12015/2 United Kingdom MRC_ Medical Research Council; United Kingdom WT_ Wellcome Trust
فهرسة مساهمة:	Keywords: Adiposity; Breast milk; Breast-feeding; Early life; Infant growth; Intake; Macronutrient; Nutrition; Weight gain
المشرفين على المادة:	0 (Carbohydrates)
تواريخ الأحداث:	Date Created: 20221019 Date Completed: 20230607 Latest Revision: 20240214
رمز التحديث:	20240214
مُعرف محوري في PubMed:	PMC10244014
DOI:	10.1017/S0007114522003178
PMID:	36259139
قاعدة البيانات:	MEDLINE

Find this article in full text from ProQuest

Full Text Finder

الوصف
تدمد:	1475-2662
DOI:	10.1017/S0007114522003178