دورية أكاديمية
Obsessive Compulsive Disorder and Bipolar Disorder Comorbidity: A Comparative Study.
العنوان: | Obsessive Compulsive Disorder and Bipolar Disorder Comorbidity: A Comparative Study. |
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المؤلفون: | Khalkhali M; Department of Psychiatry, Kavosh Cognitive Behavior Sciences and Addiction Research Center, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran., Vaghari S; Department of Psychiatry, Kavosh Cognitive Behavior Sciences and Addiction Research Center, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran., Zare R; Neuroscience Research Center, Guilan University of Medical Sciences, Rasht, Iran., Kafi Masouleh SM; Department of Psychology, University of Guilan, Rasht, Iran. |
المصدر: | Iranian journal of psychiatry [Iran J Psychiatry] 2022 Apr; Vol. 17 (2), pp. 127-135. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Psychiatry & Psychology Research Center, Tehran University of Medical Sciences Country of Publication: Iran NLM ID: 101302041 Publication Model: Print Cited Medium: Print ISSN: 1735-4587 (Print) Linking ISSN: 17354587 NLM ISO Abbreviation: Iran J Psychiatry Subsets: PubMed not MEDLINE |
أسماء مطبوعة: | Original Publication: Tehran : Psychiatry & Psychology Research Center, Tehran University of Medical Sciences |
مستخلص: | Objective: One of the difficult comorbidity of Obsessive-Compulsive disorder (OCD) to manage is bipolar disorder (BD). Results of previous studies on OCD-BD comorbidity may have been affected by different clinical definitions of OCD-BD, small or different sample sizes, different thresholds for including BD patients and different accuracies in OCD diagnosing. We tried to reduce limitations of previous studies and hypothesized that the OCD-BD group is a unique category and can be associated with greater levels of severity, episodic course of illness, more hostility and suicidal behaviors and different dimensions of OC symptoms. Method : We compared 44 OCD-BD patients with 94 OCD patients who had completed at least a 24-month follow-up period. Clinical interviews and rating scales, and obtaining information from clinical charts were used to assess the patients. Life chartings of OCD and BD course were made for each patient and were categorized into four groups based on the clinical course of OCD. Results: OCD-BD was characterized by a more continuous course, higher dysfunction, suicide and hostility scores. OC aggressive symptoms, having first-degree relatives with OCD and comorbidity of any anxiety disorders were associated with a reduction in odds of belonging to the OCD-BD group. Conclusion: OCD-BD can be considered a unique category with greater morbidity and a more episodic course of OCD. Further research is recommended for exploring potential biological, social and psychological factors along with OCD-BD comorbidity. (Copyright © 2022 Tehran University of Medical Sciences. Published by Tehran University of Medical Sciences.) |
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فهرسة مساهمة: | Keywords: Bipolar Disorder; Comorbidity; Obsessive-Compulsive Disorder |
تواريخ الأحداث: | Date Created: 20221020 Latest Revision: 20221021 |
رمز التحديث: | 20231215 |
مُعرف محوري في PubMed: | PMC9533353 |
DOI: | 10.18502/ijps.v17i2.8902 |
PMID: | 36262755 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1735-4587 |
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DOI: | 10.18502/ijps.v17i2.8902 |