دورية أكاديمية

Periodontitis and Its Inflammatory Changes Linked to Various Systemic Diseases: A Review of Its Underlying Mechanisms.

التفاصيل البيبلوغرافية
العنوان: Periodontitis and Its Inflammatory Changes Linked to Various Systemic Diseases: A Review of Its Underlying Mechanisms.
المؤلفون: Bhuyan R; Department of Oral Pathology & Microbiology, IMS and SUM Hospital, Siksha 'O' Anusandhan University (Deemed to be), Bhubaneswar 751003, India.; Department of Medical Research, IMS and SUM Hospital, Siksha 'O' Anusandhan University (Deemed to be), Bhubaneswar 751003, India., Bhuyan SK; Institute of Dental Sciences, Siksha 'O' Anusandhan University (Deemed to be), Bhubaneswar 751003, India., Mohanty JN; School of Applied Sciences, Centurion University of Technology and Management, Jatni, Bhubaneswar 752050, India., Das S; Department of Human and Clinical Anatomy, College of Medicine & Health Sciences, Sultan Qaboos University, Muscat 123, Oman., Juliana N; Faculty of Medicine and Health Sciences, Universiti Sains Islam Malaysia, Nilai 71800, Malaysia., Juliana IF; Institute of Medical Science Technology, Universiti Kuala Lumpur, Kuala Lumpur 50250, Malaysia.
المصدر: Biomedicines [Biomedicines] 2022 Oct 21; Vol. 10 (10). Date of Electronic Publication: 2022 Oct 21.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101691304 Publication Model: Electronic Cited Medium: Print ISSN: 2227-9059 (Print) Linking ISSN: 22279059 NLM ISO Abbreviation: Biomedicines Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI AG, [2013]-
مستخلص: Periodontitis is a chronic inflammatory disease of the gums. The incidence of periodontitis is increasing all over the world. In patients with periodontitis, there is gradual destruction of the periodontal ligament and the alveolar bone, and later, in advanced stages, there is tooth loss. Different microorganisms, the host's immune response, and various environmental factors interact in the progression of this chronic inflammatory disease. In the present review, we discuss the epidemiology, clinical features, diagnosis, and complications of periodontitis. We also discuss the association of chronic inflammation found in periodontitis with various other systemic diseases, which include cardiovascular, respiratory, diabetes, Alzheimer's, cancer, adverse pregnancy, and multiple myeloma, and also highlight microbial carcinogenesis and the microRNAs involved. The latest updates on the molecular mechanism, possible biomarkers, and treatment procedures may be beneficial for diagnostic and therapeutic purposes.
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فهرسة مساهمة: Keywords: infection; management; mechanisms; oral; pathology; periodontitis
تواريخ الأحداث: Date Created: 20221027 Latest Revision: 20221030
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC9599402
DOI: 10.3390/biomedicines10102659
PMID: 36289921
قاعدة البيانات: MEDLINE
الوصف
تدمد:2227-9059
DOI:10.3390/biomedicines10102659