تقرير
Three-in-one incidence of hepatocellular carcinoma, cholangiocellular carcinoma, and neuroendocrine carcinoma: A case report.
| العنوان: | Three-in-one incidence of hepatocellular carcinoma, cholangiocellular carcinoma, and neuroendocrine carcinoma: A case report. |
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| المؤلفون: | Wu Y; Department of Intervention, The Affiliated Hospital of Zunyi Medical University, Zunyi 563000, Guizhou Province, China., Xie CB; Department of Intervention, The Affiliated Hospital of Zunyi Medical University, Zunyi 563000, Guizhou Province, China., He YH; Department of Infection, The Affiliated Hospital of Zunyi Medical University, Zunyi 563000, Guizhou Province, China., Ke D; Department of Intervention, The Affiliated Hospital of Zunyi Medical University, Zunyi 563000, Guizhou Province, China., Huang Q; Department of Pathology, The Affiliated Hospital of Zunyi Medical University, Zunyi 563000, Guizhou Province, China., Zhao KF; Department of Intervention, The Affiliated Hospital of Zunyi Medical University, Zunyi 563000, Guizhou Province, China. zhaokaifei8943@sina.com., Shi RS; Department of Intervention, The Affiliated Hospital of Zunyi Medical University, Zunyi 563000, Guizhou Province, China. |
| المصدر: | World journal of clinical cases [World J Clin Cases] 2022 Oct 16; Vol. 10 (29), pp. 10575-10582. |
| نوع المنشور: | Case Reports |
| اللغة: | English |
| بيانات الدورية: | Publisher: Baishideng Publishing Group Country of Publication: United States NLM ID: 101618806 Publication Model: Print Cited Medium: Print ISSN: 2307-8960 (Print) Linking ISSN: 23078960 NLM ISO Abbreviation: World J Clin Cases Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Publication: 2014-: Pleasanton, CA : Baishideng Publishing Group Original Publication: Hong Kong, China : Baishideng Publishing Group Co., Limited, [2013]- |
| مستخلص: | Background: Primary hepatic neuroendocrine carcinoma (NEC) is rare, and a combination with hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA) is extremely rare. To date, only four combination cases have been reported. The present paper describes the fifth patient. Case Summary: A 32-year-old Chinese man with chronic hepatitis B was hospitalized for persistent upper abdominal pain. Abdominal computed tomography (CT) examination revealed a liver mass. The tumor was located in the 7 th and 8 th segments of the liver, and CT and magnetic resonance imaging findings were consistent with the diagnosis of HCC. Laboratory examinations revealed the following: Alanine aminotransferase, 243 U/L; aspartate aminotransferase, 167 U/L; alpha-fetoprotein, 4519 μg/L. Laparoscopic right lobe hepatectomy was performed on the liver mass. Postoperative pathology showed low differentiation HCC plus medium and low differentiation CCA combined with NEC. One month after the surgery, the patient suffered from epigastric pain again. Liver metastasis was detected by CT, and tumor transcatheter arterial chemoembolization was performed. Unfortunately, the liver tumor was progressively increased and enlarged, and after 1 mo, the patient died of liver failure. Conclusion: This is a rare case, wherein the tumor is highly aggressive, grows rapidly, and metastasizes in a short period. Imaging and laboratory tests can easily misdiagnose or miss such cases; thus, the final diagnosis relies on pathology. Competing Interests: Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article. (©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.) |
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| فهرسة مساهمة: | Keywords: Case report; Cholangiocarcinoma; Cholangiocellular carcinoma; Combined hepatocellular-cholangiocarcinoma; Hepatocellular carcinoma; Mixed neuroendocrine neoplasm; Neuroendocrine carcinoma |
| تواريخ الأحداث: | Date Created: 20221031 Latest Revision: 20221102 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC9602243 |
| DOI: | 10.12998/wjcc.v10.i29.10575 |
| PMID: | 36312494 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 2307-8960 |
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| DOI: | 10.12998/wjcc.v10.i29.10575 |