دورية أكاديمية
Efficacy of ganciclovir versus foscarnet in ganciclovir-resistant cytomegalovirus retinitis: A case report.
| العنوان: | Efficacy of ganciclovir versus foscarnet in ganciclovir-resistant cytomegalovirus retinitis: A case report. |
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| المؤلفون: | Lee HJ; Department of Ophthalmology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea., Woo SJ; Department of Ophthalmology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.; Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea. |
| المصدر: | European journal of ophthalmology [Eur J Ophthalmol] 2023 Sep; Vol. 33 (5), pp. NP105-NP108. Date of Electronic Publication: 2022 Oct 30. |
| نوع المنشور: | Case Reports; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: SAGE Publishing Country of Publication: United States NLM ID: 9110772 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1724-6016 (Electronic) Linking ISSN: 11206721 NLM ISO Abbreviation: Eur J Ophthalmol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2018- : Thousand Oaks, CA : SAGE Publishing Original Publication: Milano ; Birmingham, AL : Wichtig, c1991- |
| مواضيع طبية MeSH: | Cytomegalovirus Retinitis*/diagnosis , Cytomegalovirus Retinitis*/drug therapy , Ganciclovir*/therapeutic use , Antiviral Agents*/therapeutic use , Foscarnet*/therapeutic use, Humans ; Male ; Middle Aged ; Treatment Outcome |
| مستخلص: | Purpose: To report a case of cytomegalovirus (CMV) retinitis improved by treatment with ganciclovir in a patient with ganciclovir-resistant CMV infection associated with Good syndrome. Study Design: Case report. Result: A 52-year-old gentleman with Good syndrome presented with visual disturbance in his right eye. He had a history of receiving intravitreal ganciclovir treatment with CMV retinitis a year ago. During treatment for CMV colitis three months ago, in systemic blood, UL97 mutation was identified and improved after changing treatment from ganciclovir to foscarnet. CMV retinitis recurred, and intravitreal ganciclovir injection was performed but there was no improvement. Therefore, the treatment was changed to foscarnet, but retinal infiltration progressed. Accordingly, it was changed to ganciclovir again and as a result, the progression of retinitis could be stopped. Conclusions: Even in the case of CMV retinitis, which has been genetically confirmed to be ganciclovir resistance in systemic blood, ganciclovir treatment can be considered if other anti-CMV agents are not effective. |
| فهرسة مساهمة: | Keywords: Retina - medical therapies; cytomegalovirus retinitis; ganciclovir; good syndrome; retinal herpetic infections |
| المشرفين على المادة: | P9G3CKZ4P5 (Ganciclovir) 0 (Antiviral Agents) 364P9RVW4X (Foscarnet) |
| تواريخ الأحداث: | Date Created: 20221031 Date Completed: 20231026 Latest Revision: 20231026 |
| رمز التحديث: | 20231027 |
| DOI: | 10.1177/11206721221136316 |
| PMID: | 36314436 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1724-6016 |
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| DOI: | 10.1177/11206721221136316 |