دورية أكاديمية
Temporal fluctuations of cardiovascular parameters after intravitreal injections.
| العنوان: | Temporal fluctuations of cardiovascular parameters after intravitreal injections. |
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| المؤلفون: | Chiu HI; Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC., Chou YB; Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.; School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC., Lin TC; Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.; School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC., Chiou SH; Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.; School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC.; Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC., Chen SJ; Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.; School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC., Hwang DK; Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.; School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC. |
| المصدر: | Journal of the Chinese Medical Association : JCMA [J Chin Med Assoc] 2022 Nov 01; Vol. 85 (11), pp. 1088-1092. Date of Electronic Publication: 2022 Nov 02. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wolters Kluwer Health Country of Publication: Netherlands NLM ID: 101174817 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1728-7731 (Electronic) Linking ISSN: 17264901 NLM ISO Abbreviation: J Chin Med Assoc Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2019- : [Alphen aan den Rijn, The Netherlands] : Wolters Kluwer Health Original Publication: Taipei, Taiwan : Chinese Medical Association, c2003- |
| مواضيع طبية MeSH: | Hypertension*/drug therapy , Retinal Diseases* , Cataract*, Humans ; Aged ; Intravitreal Injections ; Retrospective Studies ; Blood Pressure |
| مستخلص: | Background: Despite the effectiveness of intravitreal injection (IVI) of anti-vascular endothelial growth factor in treating retinal diseases, there remains a paucity of evidence on potential systemic risks associated with this procedure. This study aims to investigate cardiovascular parameters and the risk of hypertensive urgency after IVIs. Methods: Patients who received IVIs for retinal/macular diseases were enrolled retrospectively. Patients who received cataract surgeries were enrolled as controls. Systolic and diastolic blood pressure (BP) and heart rate were measured 10 minutes before, immediately after, and more than 30 minutes after IVIs and cataract surgery. Multivariate analysis was performed to evaluate risk factors for hypertensive urgency. Results: Seventy patients who received IVIs and 95 patients who received cataract surgeries were enrolled. A higher preoperative systolic BP was found in the IVI groups than in the control group (147.0 ± 22.9 vs 136.3 ± 21.8 mmHg, respectively). The patients who received IVIs had a higher increase in perioperative systolic BP immediately after the procedure than the controls (17.43 ± 20.53 mmHg vs 9.11 ± 18.92 mmHg, p = 0.009). The IVI procedure (odds ratio [OR] 4.84, p = 0.008), preoperative systolic BP ≥160 mmHg (OR 17.891, p = 0.001, compared to preoperative systolic BP <140 mmHg), and underlying hypertension (OR 3.305, p = 0.041) were risk factors for hypertensive urgency immediately after the IVIs. Conclusion: We found a transient increase in BP after IVIs, which may have been associated with hypertensive urgency and related cardiovascular disorders in older patients and in those with relevant comorbidities. Clinicians should pay more attention to these patients before performing IVIs. Competing Interests: Conflicts of interest: Dr. Shih-Hwa Chiou, an editorial board member at Journal of the Chinese Medical Association, had no role in the peer review process of or decision to publish this article. The other authors declare that they have no conflicts of interest related to the subject matter or materials discussed in this article. (Copyright © 2022, the Chinese Medical Association.) |
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| تواريخ الأحداث: | Date Created: 20221107 Date Completed: 20221109 Latest Revision: 20221206 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1097/JCMA.0000000000000780 |
| PMID: | 36343274 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1728-7731 |
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| DOI: | 10.1097/JCMA.0000000000000780 |