دورية أكاديمية

Prevalence and risk factors associated with different comorbidities in obese children and adolescents.

التفاصيل البيبلوغرافية
العنوان: Prevalence and risk factors associated with different comorbidities in obese children and adolescents.
المؤلفون: López-Galisteo JP; Facultad de Medicina, Universidad Autónoma de Madrid, Madrid, Spain., Gavela-Pérez T; Unidad de Endocrinología Infantil, Servicio de Pediatría, Instituto de Investigación Sanitaria Fundación Jiménez Díaz, Madrid, Spain., Mejorado-Molano FJ; Unidad de Endocrinología Infantil, Servicio de Pediatría, Instituto de Investigación Sanitaria Fundación Jiménez Díaz, Madrid, Spain., Pérez-Segura P; Unidad de Endocrinología Infantil, Servicio de Pediatría, Instituto de Investigación Sanitaria Fundación Jiménez Díaz, Madrid, Spain., Aragón-Gómez I; Unidad de Endocrinología Infantil, Servicio de Pediatría, Instituto de Investigación Sanitaria Fundación Jiménez Díaz, Madrid, Spain., Garcés C; Laboratorio de Lípidos, Instituto de Investigación Sanitaria Fundación Jiménez Díaz, Madrid, Spain., Soriano-Guillén L; Unidad de Endocrinología Infantil, Servicio de Pediatría, Instituto de Investigación Sanitaria Fundación Jiménez Díaz, Madrid, Spain. Electronic address: leandro.soriano@uam.es.
المصدر: Endocrinologia, diabetes y nutricion [Endocrinol Diabetes Nutr (Engl Ed)] 2022 Oct; Vol. 69 (8), pp. 566-575. Date of Electronic Publication: 2022 Nov 05.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Country of Publication: Spain NLM ID: 101717565 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2530-0180 (Electronic) Linking ISSN: 25300180 NLM ISO Abbreviation: Endocrinol Diabetes Nutr (Engl Ed) Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [Barcelona] : [Elsevier España], 2017-
مواضيع طبية MeSH: Pediatric Obesity*/complications , Pediatric Obesity*/epidemiology , Vitamin D Deficiency*/epidemiology , Dyslipidemias*/epidemiology , Hypertension*/epidemiology, Female ; Humans ; Child ; Adolescent ; Male ; Prevalence ; Body Mass Index ; Risk Factors
مستخلص: Introduction: Different obesity-related comorbidities already present in childhood, such as: vitamin D deficiency, impaired carbohydrate metabolism, dyslipidaemia, arterial hypertension and non-alcoholic steatohepatitis. In this study, we aim to analyse the prevalence of comorbidities and to determine the predictive factors that affect these comorbidities.
Material and Methods: Anthropometric, demographic and biochemical variables were collected from obese patients between six and 18 years of age. Subsequently, a statistical analysis was performed to describe the characteristics of the patients and the prevalence of comorbidities, as well as their predictive factors.
Results: A total of 158 obese children (76 boys and 82 girls) with a mean age at diagnosis of 12.48 years and a BMI Z-score of +3.24 SDS were included. The most prevalent comorbidities were vitamin D deficiency (64.2%), insulin resistance (45.1%), dyslipidaemia (32.2%), hyperuricaemia (18.5%) and arterial hypertension (15%). Age, BMI Z-score, percentage of fat mass and male sex have been found to be predictors of these comorbidities.
Conclusion: Obese children and adolescents have a high prevalence of comorbidities. Once the diagnosis of obesity has been established, it would be very useful to identify early those patients with a higher risk of comorbidities, knowing their relationship with sex, age, BMI Z-score, percentage of fat mass and pubertal stage.
(Copyright © 2022 SEEN and SED. Published by Elsevier España, S.L.U. All rights reserved.)
فهرسة مساهمة: Keywords: Arterial hypertension; Childhood obesity; Comorbidities; Comorbilidades; Dislipemia; Dyslipidaemia; Déficit de vitamina D; Hipertensión arterial; Hiperuricemia; Hyperuricaemia; Insulin resistance; Insulinorresistencia; Obesidad infantil; Vitamin D deficiency
تواريخ الأحداث: Date Created: 20221108 Date Completed: 20221201 Latest Revision: 20221201
رمز التحديث: 20221213
DOI: 10.1016/j.endien.2021.10.012
PMID: 36347797
قاعدة البيانات: MEDLINE
الوصف
تدمد:2530-0180
DOI:10.1016/j.endien.2021.10.012