دورية أكاديمية
Comparison of the clinical performance of a hybrid Alba 4D and the AMC-4 locoregional hyperthermia systems.
| العنوان: | Comparison of the clinical performance of a hybrid Alba 4D and the AMC-4 locoregional hyperthermia systems. |
|---|---|
| المؤلفون: | Bakker A; Department of Radiation Oncology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Cancer Center Amsterdam, University of Amsterdam, Amsterdam, The Netherlands., Zweije R; Department of Radiation Oncology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Cancer Center Amsterdam, University of Amsterdam, Amsterdam, The Netherlands., Kok HP; Department of Radiation Oncology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Cancer Center Amsterdam, University of Amsterdam, Amsterdam, The Netherlands., Stalpers LJA; Department of Radiation Oncology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Cancer Center Amsterdam, University of Amsterdam, Amsterdam, The Netherlands., Westerveld GH; Department of Radiation Oncology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Cancer Center Amsterdam, University of Amsterdam, Amsterdam, The Netherlands.; Department of Radiation Oncology, Erasmus MC, Rotterdam, The Netherlands., Hinnen KA; Department of Radiation Oncology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Cancer Center Amsterdam, University of Amsterdam, Amsterdam, The Netherlands., van Tienhoven G; Department of Radiation Oncology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Cancer Center Amsterdam, University of Amsterdam, Amsterdam, The Netherlands., Kolff MW; Department of Radiation Oncology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Cancer Center Amsterdam, University of Amsterdam, Amsterdam, The Netherlands., Crezee H; Department of Radiation Oncology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Cancer Center Amsterdam, University of Amsterdam, Amsterdam, The Netherlands. |
| المصدر: | International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group [Int J Hyperthermia] 2022; Vol. 39 (1), pp. 1408-1414. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Informa Healthcare Country of Publication: England NLM ID: 8508395 Publication Model: Print Cited Medium: Internet ISSN: 1464-5157 (Electronic) Linking ISSN: 02656736 NLM ISO Abbreviation: Int J Hyperthermia Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: London : Informa Healthcare Original Publication: London ; Philadelphia : Taylor & Francis, c1985- |
| مواضيع طبية MeSH: | Hyperthermia, Induced*/methods , Uterine Cervical Neoplasms*/therapy, Female ; Humans ; Temperature ; Italy ; Combined Modality Therapy |
| مستخلص: | Objective: The in-house developed 70 MHz AMC-4 locoregional hyperthermia system has been in clinical use since 1984. This device was recently commercialized as the Alba 4D (Medlogix ® , Rome, Italy), with a similar geometrical 4-waveguide design. At the time of this study a hybrid Alba 4D was installed at our center, which incorporated elements of the AMC-4. This study aims to compare clinical performance of both devices. Methods: During one year after clinical acceptance of the hybrid Alba 4D, both devices were used for treatment delivery in patients scheduled for locoregional hyperthermia. Each patient started with the AMC-4, next sessions were allocated to either device. Possible differences between Alba 4D and AMC-4 sessions in power, achieved temperature T0, T10, T50, T90, T100, treatment time and complaints per session, were evaluated using linear mixed models (LMMs) for repeated measures with patient as random effect. Results: From March 2018 to April 2019, eleven patients with cervical, pancreatic, vaginal carcinoma and uterine leiomyosarcoma received 27 locoregional hyperthermia sessions with the Alba 4D and 34 sessions with the AMC-4. Median number of sessions per patient was 5 (range 3-13). Treatment results for both devices were not significantly different: T50 was 40.5 ± 1.0 °C vs. 40.8 ± 0.7 °C, applied power was 500 ± 79 W vs. 526 ± 108 W, for the Alba 4D vs. AMC-4, respectively. Conclusion: Results of the first patients treated with the hybrid Alba 4D demonstrated comparable clinical performance of the Alba 4D and AMC-4 locoregional hyperthermia systems, and both devices are expected to yield similar favorable clinical results. |
| فهرسة مساهمة: | Keywords: AMC-4 system; Alba 4D system; Hyperthermia; clinical performance; locoregional hyperthermia systems |
| تواريخ الأحداث: | Date Created: 20221110 Date Completed: 20221114 Latest Revision: 20221205 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1080/02656736.2022.2140841 |
| PMID: | 36355063 |
| قاعدة البيانات: | MEDLINE |
PDF full text from Publisher 
Full Text Finder | تدمد: | 1464-5157 |
|---|---|
| DOI: | 10.1080/02656736.2022.2140841 |