دورية أكاديمية
أعرض في EDS

Reproductive Resumption in Winter and Spring Related to MTNR1A Gene Polymorphisms in Sarda Sheep.

التفاصيل البيبلوغرافية
العنوان: Reproductive Resumption in Winter and Spring Related to MTNR1A Gene Polymorphisms in Sarda Sheep.
المؤلفون: Mura MC; Department of Veterinary Medicine of Sassari, University of Sassari, Via Vienna 2, 07100 Sassari, Italy., Cosso G; Department of Veterinary Medicine of Sassari, University of Sassari, Via Vienna 2, 07100 Sassari, Italy., Pulinas L; Department of Veterinary Medicine of Sassari, University of Sassari, Via Vienna 2, 07100 Sassari, Italy., Carcangiu V; Department of Veterinary Medicine of Sassari, University of Sassari, Via Vienna 2, 07100 Sassari, Italy., Luridiana S; Department of Veterinary Medicine of Sassari, University of Sassari, Via Vienna 2, 07100 Sassari, Italy.
المصدر: Animals : an open access journal from MDPI [Animals (Basel)] 2022 Oct 26; Vol. 12 (21). Date of Electronic Publication: 2022 Oct 26.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Molecular Diversity Preservation International Country of Publication: Switzerland NLM ID: 101635614 Publication Model: Electronic Cited Medium: Print ISSN: 2076-2615 (Print) Linking ISSN: 20762615 NLM ISO Abbreviation: Animals (Basel) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : Molecular Diversity Preservation International, 2011-
مستخلص: The aim of the present research was to evaluate the association between the SNPs rs430181568 and rs407388227 located in the MTNR1A gene with the reproductive recovery of Sarda sheep in different months of ram introduction in the flock (February, March, April and May). In order to address this research gap, we selected two farms, each of which consisted of approximately 1000 animals; a total of 800 ewes (400 for each farm) were genotyped for the two single nucleotide polymorphisms rs430181568 and rs407388227 located in the exon 2 of the MTNR1A. These SNPs are completely linked; thus, each genotype of rs430181568 corresponded to the same genotype for rs407388227. Among the genotyped animals, 240 individuals were selected and divided into four homogeneous groups (A, B, C and D) of 60 subjects, each group based on age (range 3−6 years old), body condition score (BCS) (range 2.0−4.0) and genotype (20 ewes carrying CC/CC, 20 CT/CT and 20 TT/TT genotype). The dates of the ram introduction in each group were 15 February, 15 March, 15 April and 15 May, respectively. In all groups, the lambing date and the number of lambs born from 150 to 220 days after the ram introduction were recorded. In all the groups, the genotypes CC/CC and CT/CT of the polymorphism (rs430181568 and rs407388227) showed the greatest fertility (the ratio between the number of lambed ewes and the ewes exposed to the rams) (p < 0.01) and the shortest distance between ram introduction to lambing (p < 0.01), compared with the TT/TT genotype. In conclusion, we determined that the polymorphisms rs430181568 and rs407388227 were associated with reproductive recovery, after ram introduction, even in February and March, months subsequent to the photorefractoriness period.
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فهرسة مساهمة: Keywords: Sarda breed sheep; fertility rate; male effect; melatonin; reproductive recovery
تواريخ الأحداث: Date Created: 20221111 Latest Revision: 20230308
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC9654450
DOI: 10.3390/ani12212947
PMID: 36359071
قاعدة البيانات: MEDLINE
الوصف
تدمد:2076-2615
DOI:10.3390/ani12212947