Chitosan/Lactic Acid Systems: Liquid Crystalline Behavior, Rheological Properties, and Riboflavin Release In Vitro.

التفاصيل البيبلوغرافية
العنوان:	Chitosan/Lactic Acid Systems: Liquid Crystalline Behavior, Rheological Properties, and Riboflavin Release In Vitro.
المؤلفون:	Selivanova NM; Department of Physical and Colloid Chemistry, Kazan National Research Technological University, Kazan 420015, Russia., Galeeva AI; Department of Physical and Colloid Chemistry, Kazan National Research Technological University, Kazan 420015, Russia., Galyametdinov YG; Department of Physical and Colloid Chemistry, Kazan National Research Technological University, Kazan 420015, Russia.; Zavoisky Physical-Technical Institute, FRC Kazan Scientific Center of RAS, Kazan 420029, Russia.
المصدر:	International journal of molecular sciences [Int J Mol Sci] 2022 Oct 30; Vol. 23 (21). Date of Electronic Publication: 2022 Oct 30.
نوع المنشور:	Journal Article
اللغة:	English
بيانات الدورية:	Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
أسماء مطبوعة:	Original Publication: Basel, Switzerland : MDPI, [2000-
مواضيع طبية MeSH:	Chitosan* , Liquid Crystals*/chemistry, Lactic Acid ; Rheology ; Ions ; Riboflavin
مستخلص:	Chitosan or its derivatives exhibit lyotropic liquid crystalline mesophases under certain conditions due to its semi-rigid structures. This work describes the development of chitosan-based biocompatible systems that include new components: lactic acid and non-ionic surfactants. Polarized optical microscopy studies revealed that these systems are capable of forming gels or lyotropic liquid crystals (LLCs) in a certain range of chitosan and lactic acid concentrations. According to the viscosity studies, the rheological flow of the LLCs can be accurately described by the Casson flow model. The intermolecular interactions of the LLC components were studied by FTIR spectroscopy. According to the FTIR data, hydrogen bonding is supposed to be responsible for the formation of the LLCs. In the studied systems, this LLC complex exists as the [ChitH ⁺ ·CH 3 -CH(OH)-COO ^- ] ion pair. The studied gel and LLCs were shown to possess the most prolonged release capabilities for riboflavin among similar binary LLC systems. The supramolecular organization and rheological characteristics of the studied chitosan-based systems were found to affect the release of riboflavin.
References:	Adv Sci (Weinh). 2022 Apr;9(10):e2105373. (PMID: 35112798) J Phys Chem B. 2020 Apr 2;124(13):2715-2722. (PMID: 32207304) Int J Pharm. 2009 Jan 5;365(1-2):190-9. (PMID: 18790030) Int J Biol Macromol. 2022 Jan 1;194:521-538. (PMID: 34822820) Pharmaceutics. 2021 Apr 20;13(4):. (PMID: 33924046) ACS Omega. 2022 Sep 16;7(38):34022-34033. (PMID: 36188292) Expert Opin Drug Deliv. 2020 Dec;17(12):1781-1805. (PMID: 32886531) Drug Discov Today. 2010 Dec;15(23-24):1032-40. (PMID: 20934534) RSC Adv. 2018 Feb 13;8(13):6978-6987. (PMID: 35540315) Chem Pharm Bull (Tokyo). 2015;63(2):88-94. (PMID: 25748779) Int J Mol Sci. 2020 Jan 31;21(3):. (PMID: 32023913) Langmuir. 2005 Apr 12;21(8):3322-33. (PMID: 15807570) Drug Des Devel Ther. 2017 Feb 13;11:393-406. (PMID: 28243062) J Control Release. 2003 Nov 18;93(1):1-13. (PMID: 14602417) Carbohydr Polym. 2022 Apr 15;282:119100. (PMID: 35123739) J Phys Chem B. 2012 Jan 19;116(2):735-42. (PMID: 22066818) ACS Nano. 2019 Jun 25;13(6):6178-6206. (PMID: 31082192) Soft Matter. 2015 Oct 21;11(39):7809-16. (PMID: 26314681) Soft Matter. 2006 Aug 16;2(9):760-769. (PMID: 32680216) Mol Membr Biol. 2010 Oct;27(7):247-59. (PMID: 21028936) Cancers (Basel). 2020 Jan 27;12(2):. (PMID: 32012715) Nanoscale. 2013 Apr 21;5(8):3103-11. (PMID: 23515527) Carbohydr Polym. 2022 Jan 1;275:118689. (PMID: 34742416) Biomacromolecules. 2009 Jan 12;10(1):166-73. (PMID: 19067537) Int J Nanomedicine. 2015 Jul 30;10:4815-24. (PMID: 26257519)
معلومات مُعتمدة:	18-13-00112 Russian Science Foundation; 075-15-2021- 699 Ministry of Science and Higher Education of the Russian Federation
فهرسة مساهمة:	Keywords: Casson flow model; chitosan; lactic acid; lyotropic liquid crystals; riboflavin release
المشرفين على المادة:	9012-76-4 (Chitosan) 33X04XA5AT (Lactic Acid) 0 (Ions) TLM2976OFR (Riboflavin)
تواريخ الأحداث:	Date Created: 20221111 Date Completed: 20221114 Latest Revision: 20221117
رمز التحديث:	20231215
مُعرف محوري في PubMed:	PMC9654581
DOI:	10.3390/ijms232113207
PMID:	36362002
قاعدة البيانات:	MEDLINE

Find this article in full text from ProQuest

Full Text Finder

الوصف
تدمد:	1422-0067
DOI:	10.3390/ijms232113207