دورية أكاديمية
أعرض في EDS

Is Vestibular Neuropathy Rather a Neuritis?

التفاصيل البيبلوغرافية
العنوان: Is Vestibular Neuropathy Rather a Neuritis?
المؤلفون: Haeussler SM; Otolaryngology - Head and Neck Surgery, UKE Hamburg, Hamburg, DEU., Zabaneh SI; Otolaryngology - Head and Neck Surgery, Charité Berlin, Berlin, DEU., Stegemann M; Infectious Disease, Charité Berlin, Berlin, DEU., Olze H; Otolaryngology, Charité Berlin, Berlin, DEU., Böttcher A; Otolaryngology - Head and Neck Surgery, UKE Hamburg, Hamburg, DEU., Stölzel K; Otolaryngology - Head and Neck Surgery, UKE Hamburg, Hamburg, DEU.
المصدر: Cureus [Cureus] 2022 Oct 05; Vol. 14 (10), pp. e29959. Date of Electronic Publication: 2022 Oct 05 (Print Publication: 2022).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Cureus, Inc Country of Publication: United States NLM ID: 101596737 Publication Model: eCollection Cited Medium: Print ISSN: 2168-8184 (Print) Linking ISSN: 21688184 NLM ISO Abbreviation: Cureus Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Palo Alto, CA : Cureus, Inc.
مستخلص: Background/objectives Vestibular neuritis (VN) is one of the most common causes of peripheral vestibular neuropathy. The goal of this study is to investigate the possible infectious causes of VN in a large cohort of patients. Material and methods In total, 98 consecutive VN patients were enrolled in this retrospective study over a four-year period (04/2015-04/2019). Diagnosis of VN was made by clinical examination and functional diagnostics. We focused on infectious causes such as neurotropic viruses and Lyme disease (LD) and evaluated infection parameters as well as the concomitant diseases. Results In this cohort, we found pathologically elevated leukocytes or C-reactive protein (CRP) levels, and/or acute herpes simplex virus (HSV) infection, cytomegalovirus (CMV) infection and LD in 42 patients (42.85%). Leukocytes were elevated in 39 of 98 patients (39.8%) and the mean count was 9717 ± 2991 /μl. The group comparison between patients with vestibular loss (n=42) and patients with vestibular hypofunction (n=45) revealed a significant difference in regard to elevated leukocytes (p=0.028). In total, 28 of 53 patients (52.8%) were positive for HSV immunoglobulin (Ig) G and four of 53 patients were positive for HSV IgM (7.5%). Six of 53 patients (11.3%) were positive for LD IgM. Conclusion In this cohort, there was a large number of VN patients with infectious signs; several patients tested positive for HSV and LD. Therefore we recommend testing VN patients not only for HSV but also for LD and other neurotropic viruses. This approach enables to complement the standard VN treatment with a specific treatment.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2022, Haeussler et al.)
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فهرسة مساهمة: Keywords: head impulse test; herpes simplex; lyme's disease; vertigo diagnosis; vestibular dysfunction; vestibular neuritis
تواريخ الأحداث: Date Created: 20221116 Latest Revision: 20221117
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC9635860
DOI: 10.7759/cureus.29959
PMID: 36381739
قاعدة البيانات: MEDLINE
الوصف
تدمد:2168-8184
DOI:10.7759/cureus.29959