دورية أكاديمية
أعرض في EDS

Cirrhosis and hernia repair in a cohort of 6352 patients in a tertiary hospital: Risk assessment and survival analysis.

التفاصيل البيبلوغرافية
العنوان: Cirrhosis and hernia repair in a cohort of 6352 patients in a tertiary hospital: Risk assessment and survival analysis.
المؤلفون: Pipek LZ; Faculdade de Medicina FMUSP, Universidade de Sao Paulo, São Paulo, Brazil., Cortez VS; Faculdade de Medicina FMUSP, Universidade de Sao Paulo, São Paulo, Brazil., Taba JV; Faculdade de Medicina FMUSP, Universidade de Sao Paulo, São Paulo, Brazil., Suzuki MO; Faculdade de Medicina FMUSP, Universidade de Sao Paulo, São Paulo, Brazil., do Nascimento FS; Faculdade de Medicina FMUSP, Universidade de Sao Paulo, São Paulo, Brazil., de Mattos VC; Faculdade de Medicina FMUSP, Universidade de Sao Paulo, São Paulo, Brazil., Moraes WA; Faculdade de Medicina FMUSP, Universidade de Sao Paulo, São Paulo, Brazil., Iuamoto LR; Center of Acupuncture, Department of Orthopaedics and Traumatology, University of Sao Paulo School of Medicine, São Paulo, Brazil., Hsing WT; Center of Acupuncture, Department of Orthopaedics and Traumatology, University of Sao Paulo School of Medicine, São Paulo, Brazil., Carneiro-D'Albuquerque LA; Department of Gastroenterology, Hospital das Clínicas, HCFMUSP, São Paulo, Brazil., Meyer A; Department of Gastroenterology, Hospital das Clínicas, HCFMUSP, São Paulo, Brazil., Andraus W; Department of Gastroenterology, Hospital das Clínicas, HCFMUSP, São Paulo, Brazil.
المصدر: Medicine [Medicine (Baltimore)] 2022 Nov 11; Vol. 101 (45), pp. e31506.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 2985248R Publication Model: Print Cited Medium: Internet ISSN: 1536-5964 (Electronic) Linking ISSN: 00257974 NLM ISO Abbreviation: Medicine (Baltimore) Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Hagerstown, Md : Lippincott Williams & Wilkins
مواضيع طبية MeSH: Herniorrhaphy* , Hernia, Umbilical*/surgery, Humans ; Ascites/complications ; Tertiary Care Centers ; Treatment Outcome ; Liver Cirrhosis/complications ; Liver Cirrhosis/epidemiology ; Liver Cirrhosis/surgery ; Risk Assessment ; Survival Analysis
مستخلص: The prevalence of hernias in patient with cirrhosis can reach up to 40%. The pathophysiology of cirrhosis is closely linked to that of the umbilical hernia, but other types are also common in this population. The aim of this study is to evaluate factors that influence in the prognosis after hernia repair in patients with cirrhosis. A historical cohort of 6419 patients submitted to hernia repair was gathered. Clinical, epidemiological data and hernia characteristics were obtained. For patient with cirrhosis, data from exams, surgery and follow-up outcomes were also analyzed. Survival curves were constructed to assess the impact of clinical and surgical variables on survival. 342 of the 6352 herniated patients were cirrhotic. Patient with cirrhosis had a higher prevalence of umbilical hernia (67.5% × 24.2%, P < .001) and a lower prevalence of epigastric (1.8% × 9.0%, P < .001) and lumbar (0% × 0.18%, P = .022). There were no significant differences in relation to inguinal hernia (P = .609). Ascites was present in 70.1% of patient with cirrhosis and its prevalence was different in relation to the type of hernia (P < .001). The survival curve showed higher mortality for emergency surgery, MELD > 14 and ascites (HR 12.6 [3.79-41.65], 4.5 [2.00-10.34], and 6.1 [1.15-20.70], respectively, P < .05). Hernia correction surgery in patient with cirrhosis has a high mortality, especially when performed under urgent conditions associated with more severe clinical conditions of patients, such as the presence of ascites and elevated MELD.
Competing Interests: The authors have no funding and conflicts of interest to disclose.
(Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.)
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تواريخ الأحداث: Date Created: 20221118 Date Completed: 20221121 Latest Revision: 20230103
رمز التحديث: 20230104
مُعرف محوري في PubMed: PMC9666189
DOI: 10.1097/MD.0000000000031506
PMID: 36397364
قاعدة البيانات: MEDLINE
الوصف
تدمد:1536-5964
DOI:10.1097/MD.0000000000031506