دورية أكاديمية
ROS scavenging of SOD/CAT mimics probed by EPR and reduction of lipid peroxidation in S. cerevisiae and mouse liver, under severe hydroxyl radical stress condition.
العنوان: | ROS scavenging of SOD/CAT mimics probed by EPR and reduction of lipid peroxidation in S. cerevisiae and mouse liver, under severe hydroxyl radical stress condition. |
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المؤلفون: | Menezes LB; Departamento de Química, Universidade Federal de Santa Catarina, Florianópolis 88040-900, SC, Brazil., Segat BB; Departamento de Química, Universidade Federal de Santa Catarina, Florianópolis 88040-900, SC, Brazil., Tolentino H; LABOX, Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Florianópolis 88040-900, SC, Brazil., Pires DC; Rede Micologia RJ- FAPERJ; Departamento de Bioquímica, Instituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-909, RJ, Brazil., Mattos LMM; Rede Micologia RJ- FAPERJ; Departamento de Bioquímica, Instituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-909, RJ, Brazil., Hottum HM; Rede Micologia RJ- FAPERJ; Departamento de Bioquímica, Instituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-909, RJ, Brazil., Pereira MD; Rede Micologia RJ- FAPERJ; Departamento de Bioquímica, Instituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-909, RJ, Brazil., Latini A; LABOX, Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Florianópolis 88040-900, SC, Brazil., Horn A Jr; Departamento de Química, Universidade Federal de Santa Catarina, Florianópolis 88040-900, SC, Brazil. Electronic address: adolfo.junior@ufsc.br., Fernandes C; Departamento de Química, Universidade Federal de Santa Catarina, Florianópolis 88040-900, SC, Brazil. Electronic address: christiane.horn@ufsc.br. |
المصدر: | Journal of inorganic biochemistry [J Inorg Biochem] 2023 Feb; Vol. 239, pp. 112062. Date of Electronic Publication: 2022 Nov 05. |
نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
اللغة: | English |
بيانات الدورية: | Publisher: Elsevier Country of Publication: United States NLM ID: 7905788 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3344 (Electronic) Linking ISSN: 01620134 NLM ISO Abbreviation: J Inorg Biochem Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: New York, Elsevier. |
مواضيع طبية MeSH: | Saccharomyces cerevisiae*/metabolism , Superoxides*, Mice ; Animals ; Lipid Peroxidation ; Reactive Oxygen Species ; Hydroxyl Radical ; Copper/chemistry ; Ferric Compounds ; Hydrogen Peroxide ; Free Radicals ; Superoxide Dismutase/metabolism ; Liver/metabolism ; Pyridines |
مستخلص: | The interaction between Cu II , Fe III and Mn II complexes, derived from the ligands 1-[bis(pyridine-2-ylmethyl)amino]-3-chloropropan-2-ol (hpclnol) and bis(pyridine-2-ylmethyl)amine (bpma), and the free radical 2,2-diphenyl-1-(2,4,6-trinitrophenyl)hydrazyl (DPPH) and reactive oxygen species (ROS), was investigated by colorimetric and EPR (Electron Paramagnetic Resonance) techniques. A comparison between these results and those reported to [Mn(salen)Cl] or EUK-8 was also addressed. EPR studies allowed us the identification of intermediates species such as superoxide‑copper(I) and superoxide‑copper(II), a mixed-valence Fe III Fe II species and a 16-line feature attributed to Mn III -oxo-Mn IV species. The biomarker malondialdehyde (MDA) was determined by TBARS assay in S. cerevisiae cells, and the determination of the IC Competing Interests: Declaration of Competing Interest The authors declare that they have no any conflict of interest. (Copyright © 2022. Published by Elsevier Inc.) |
فهرسة مساهمة: | Keywords: EPR; Lipid peroxidation; Mouse liver homogenate; ROS; S. cerevisiae; SOD and CAT mimics |
المشرفين على المادة: | 94-93-9 (disalicylaldehyde ethylenediamine) 0 (Reactive Oxygen Species) 11062-77-4 (Superoxides) 3352-57-6 (Hydroxyl Radical) 789U1901C5 (Copper) 0 (Ferric Compounds) BBX060AN9V (Hydrogen Peroxide) 0 (Free Radicals) EC 1.15.1.1 (Superoxide Dismutase) 0 (Pyridines) |
تواريخ الأحداث: | Date Created: 20221120 Date Completed: 20221226 Latest Revision: 20230223 |
رمز التحديث: | 20240628 |
DOI: | 10.1016/j.jinorgbio.2022.112062 |
PMID: | 36403436 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1873-3344 |
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DOI: | 10.1016/j.jinorgbio.2022.112062 |