دورية أكاديمية
أعرض في EDS

Assessment of Tissue Adequacy by EBUS in Conjunction with PET Scan and Operator's Experience.

التفاصيل البيبلوغرافية
العنوان: Assessment of Tissue Adequacy by EBUS in Conjunction with PET Scan and Operator's Experience.
المؤلفون: Karim NA; Inova Schar Cancer Institute, University of Virginia, Fairfax, VA 22031, USA., Ullah A; Department of Pathology, Vanderbilt University Medical Center, Nashville, TN 37232, USA., Pulliam S; Department of Surgery, University of Tennessee Erlanger School of Medicine, Chattanooga, TN 37403, USA., Mostafa A; Division Internal Medicine, University of Cincinnati, Cincinnati, OH 45221, USA., Aragaki A; Division Internal Medicine, University of Cincinnati, Cincinnati, OH 45221, USA., Eubanks A; Department of Pathology, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA., Mahajan A; Inova Schar Cancer Institute, University of Virginia, Fairfax, VA 22031, USA., Shehata M; Division Internal Medicine, University of Cincinnati, Cincinnati, OH 45221, USA., Benzaquen S; Division Internal Medicine, University of Cincinnati, Cincinnati, OH 45221, USA.
المصدر: Clinics and practice [Clin Pract] 2022 Nov 20; Vol. 12 (6), pp. 942-949. Date of Electronic Publication: 2022 Nov 20.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101563282 Publication Model: Electronic Cited Medium: Print ISSN: 2039-7275 (Print) Linking ISSN: 20397275 NLM ISO Abbreviation: Clin Pract Subsets: PubMed not MEDLINE
أسماء مطبوعة: Publication: 2021- : Basel, Switzerland : MDPI
Original Publication: Pavia : PAGEPress
مستخلص: Mediastinal lymph node assessment is a crucial step in non-small cell lung cancer staging. Positron emission tomography (PET) has been the gold standard for the assessment of mediastinal lymphadenopathy, though it has limited specificity. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is quick, accurate, and a less invasive method for obtaining a diagnostic sample in contrast to mediastinoscopy. We performed a retrospective chart analysis of 171 patients to assess the adequacy of tissue obtained by EBUS for diagnosis and molecular profiling as well as the assessment of staging and lymph node (LN) stations diagnostic yield, in correlation to PET scan and the operator’s level of experience. A significantly increased tissue adequacy was observed based on the operators’ experience, with the highest adequacy noted in trained Interventional Pulmonologist (IP) (100%), followed by >5 years of experience (93.33%), and 88.89% adequacy with <5 years of experience (p = 0.0019). PET-CT scan 18F-fluorodeoxyglucose (FDG) uptake in levels 1, 2, and 3 LN had a tissue adequacy of 76.67%, 54.64%, and 35.56%, respectively (p = 0.0009). EBUS bronchoscopy method could be used to achieve an accurate diagnosis, with IP-trained operators yielding the best results. There is no correlation with PET scan positivity, indicating that both PET and EBUS are complementary methods needed for staging.
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فهرسة مساهمة: Keywords: lymph nodes; lymphadenopathy; non-small cell lung carcinoma
تواريخ الأحداث: Date Created: 20221122 Latest Revision: 20230308
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC9680420
DOI: 10.3390/clinpract12060099
PMID: 36412678
قاعدة البيانات: MEDLINE
الوصف
تدمد:2039-7275
DOI:10.3390/clinpract12060099