دورية أكاديمية
أعرض في EDS

Potentially inappropriate medications according to Marc, STOPP and PRISCUS criteria in a cohort of elderly HIV+ patients. The COMMPI project.

التفاصيل البيبلوغرافية
العنوان: Potentially inappropriate medications according to Marc, STOPP and PRISCUS criteria in a cohort of elderly HIV+ patients. The COMMPI project.
المؤلفون: García-Lloret P, Borrego-Izquierdo Y; Yolanda Borrego Izquierdo, Pharmacy Department, Gerencia de Atención Primaria. Cantabria (Spain). yolanda.borrego@scsalud.es., Manzano-García M, Cantillana-Suárez MG, Gutiérrez-Pizarraya A, Morillo-Verdugo R
المصدر: Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia [Rev Esp Quimioter] 2023 Feb; Vol. 36 (1), pp. 52-58. Date of Electronic Publication: 2022 Nov 23.
نوع المنشور: Multicenter Study; Journal Article
اللغة: English
بيانات الدورية: Publisher: Sociedad Española de Quimioterapia Country of Publication: Spain NLM ID: 9108821 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1988-9518 (Electronic) Linking ISSN: 02143429 NLM ISO Abbreviation: Rev Esp Quimioter Subsets: MEDLINE
أسماء مطبوعة: Publication: [Barcelona] : Sociedad Española de Quimioterapia
Original Publication: Barcelona : J.R. Prous, S.A., [1988-
مواضيع طبية MeSH: Potentially Inappropriate Medication List* , HIV Infections*/drug therapy , HIV Infections*/epidemiology, Male ; Humans ; Aged ; Female ; Inappropriate Prescribing ; Retrospective Studies ; Prevalence
مستخلص: Objective: The objective is to determine the prevalence of potentially inappropriate drugs according to the Marc, STOPP, and PRISCUS lists in elderly HIV patients.
Methods: It was an observational, retrospective, and multicenter study. People living with HIV 65 years or older who underwent chronic concomitant treatment were included. Descriptive and multivariate analyzes were performed to study the association between polypharmacy and potentially inappropriate medication compliance.
Results: A total of 55 patients were included, 81.8% men and a median age of 69 years (IQR: 67-73). The median number of comorbidities was 3 (IQR: 2-5) and the most frequent pattern of multimorbidity was cardiometabolic (62.9%). The predominant antiretroviral treatment was triple therapy (65.5%). Polypharmacy was present in 70.9% of the patients and 25.5% had major polypharmacy. The most frequent polypharmacy pattern was cardiovascular (69.2%). The percentage of potentially inappropriate medications according to the Marc, STOPP and PRISCUS lists was 65.5%, 30.9% and 14.5%, respectively (p<0.001). Adjusted for age and sex, polypharmacy was not independently associated with potentially inappropriate medication compliance in any of the lists.
Conclusions: Polypharmacy and potentially inappropriate medications have a high prevalence. There is great variability in the percentage according to the list applied. Age, sex, and presence of polypharmacy are not predisposing factors to the presence of potentially inappropriate medications.
(©The Author 2022. Published by Sociedad Española de Quimioterapia. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)(https://creativecommons.org/licenses/by-nc/4.0/).)
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فهرسة مساهمة: Keywords: HIV; polypharmacy; potentially inappropriate medication list
تواريخ الأحداث: Date Created: 20221123 Date Completed: 20230124 Latest Revision: 20230217
رمز التحديث: 20230217
مُعرف محوري في PubMed: PMC9910679
DOI: 10.37201/req/070.2022
PMID: 36415149
قاعدة البيانات: MEDLINE
الوصف
تدمد:1988-9518
DOI:10.37201/req/070.2022