دورية أكاديمية

Bariatric Surgery in Kidney Transplant Candidates and Recipients: Experience at an Asian Center.

التفاصيل البيبلوغرافية
العنوان: Bariatric Surgery in Kidney Transplant Candidates and Recipients: Experience at an Asian Center.
المؤلفون: Tan SYT; Department of Endocrinology, Singapore General Hospital, Singapore., Lee PC; Department of Endocrinology, Singapore General Hospital, Singapore., Ganguly S; Department of Endocrinology, Singapore General Hospital, Singapore., Kek PC; Department of Endocrinology, Singapore General Hospital, Singapore., Kee T; Department of Renal Medicine, Singapore General Hospital, Singapore.; SingHealth Duke-National University of Singapore Transplant Centre, Singapore., Ho QY; Department of Renal Medicine, Singapore General Hospital, Singapore.; SingHealth Duke-National University of Singapore Transplant Centre, Singapore., Thangaraju S; Department of Renal Medicine, Singapore General Hospital, Singapore.; SingHealth Duke-National University of Singapore Transplant Centre, Singapore.
المصدر: Journal of obesity & metabolic syndrome [J Obes Metab Syndr] 2022 Dec 30; Vol. 31 (4), pp. 325-333. Date of Electronic Publication: 2022 Nov 23.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Korean Society for the Study of Obesity Country of Publication: Korea (South) NLM ID: 101704724 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2508-7576 (Electronic) Linking ISSN: 25086235 NLM ISO Abbreviation: J Obes Metab Syndr Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Seoul : Korean Society for the Study of Obesity, [2017]-
مستخلص: Background: Kidney transplant (KT) candidates and recipients with obesity experience more frequent complications such as infection, poorer allograft outcomes, diabetes, and mortality, limiting their eligibility for transplantation. Bariatric surgery (BS) is not commonly performed among KT patients given concerns about immunosuppression absorption, wound healing, infections, and graft outcomes. Its role has not been described before in an Asian KT patient setting.
Methods: A retrospective review of patients who underwent BS at the largest KT center in Singapore from 2008 to 2020 was conducted. Metabolic outcomes, immunosuppression doses, graft outcomes, and mortality were studied.
Results: Seven patients underwent BS and KT (4 underwent BS before KT, 3 underwent BS after KT; 4 underwent sleeve gastrectomy, 3 underwent gastric bypass). Mean total weight losses of 23.8% at 1 year and 18.6% at 5 years post-BS were achieved. Among the five patients with diabetes, glycemic control improved after BS. There were no deaths in the first 90 days or graft loss in the first year after KT and BS. Patients who underwent BS after KT had no significant changes in immunosuppression dose.
Conclusion: BS can be safely performed in KT recipients and candidates and results in sustainable weight losses and improvements in metabolic comorbidities. Although no major complications were observed in our study, close monitoring of this complex group of patients is imperative.
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فهرسة مساهمة: Keywords: Bariatric surgery; Chronic kidney disease; Kidney transplantation
تواريخ الأحداث: Date Created: 20221123 Latest Revision: 20230120
رمز التحديث: 20230120
مُعرف محوري في PubMed: PMC9828702
DOI: 10.7570/jomes21090
PMID: 36416037
قاعدة البيانات: MEDLINE
الوصف
تدمد:2508-7576
DOI:10.7570/jomes21090